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The map label for this gene is hyaE

Identifier: 157160495

GI number: 157160495

Start: 1097968

End: 1098366

Strand: Direct

Name: hyaE

Synonym: EcHS_A1084

Alternate gene names: 157160495

Gene position: 1097968-1098366 (Clockwise)

Preceding gene: 157160494

Following gene: 157160496

Centisome position: 23.65

GC content: 56.64

Gene sequence:

>399_bases
ATGAGCAACGACACGCCATTTGATGCGTTGTGGCAACGAATGCTGGCGCGCGGCTGGACGCCAGTCAGTGAATCCCGTCT
TGACGACTGGCTTACGCAAGCGCCAGACGGCGTGGTGTTATTAAGCAGTGACCCGAAACGCACGCCAGAGGTCAGCGATA
ATCCGGTAATGATTGGCGAATTACTGCGCGAGTTTCCCGACTATACATGGCAGGTGGCGATTGCTGACCTTGAGCAGAGC
GAAGCCATCGGCGATCGCTTTGGCGTCTTTCGCTTTCCTGCCACTTTAGTGTTTACCGGCGGAAACTATCGCGGCGTGCT
GAATGGTATTCACCCGTGGGCGGAACTGATAAACCTGATGCGCGGGCTTGTCGAACCGCAGCAGGAGCGTGCCTCATGA

Upstream 100 bases:

>100_bases
CGGCTAATGAATCGCGCTGTCTCAATTATGACTGTCTGTCGATGGAAAATTACGAAGGCGTTCGCTTGCGCCAGTACCGG
ATGACACAGGAGGAGCAGGG

Downstream 100 bases:

>100_bases
GCGAAACTTTTTTCCATCTGCTGGGGCCAGGAACGCAACCGAACGATGACAGTTTCAGCATGAATCCACTGCCGATCACC
TGTCAGGTGAATGATGAACC

Product: hydrogenase-1 operon protein HyaE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MSNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSDPKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQS
EAIGDRFGVFRFPATLVFTGGNYRGVLNGIHPWAELINLMRGLVEPQQERAS

Sequences:

>Translated_132_residues
MSNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSDPKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQS
EAIGDRFGVFRFPATLVFTGGNYRGVLNGIHPWAELINLMRGLVEPQQERAS
>Mature_131_residues
SNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSDPKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQSE
AIGDRFGVFRFPATLVFTGGNYRGVLNGIHPWAELINLMRGLVEPQQERAS

Specific function: Not known. Could form, along with hyaD, a complex involved in the processing of the hydrogenase 1 structural operon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupG/hyaE family

Homologues:

Organism=Escherichia coli, GI1787210, Length=132, Percent_Identity=100, Blast_Score=270, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYAE_ECOLI (P19931)

Other databases:

- EMBL:   M34825
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   JV0076
- RefSeq:   AP_001605.1
- RefSeq:   NP_415495.1
- PDB:   2HFD
- PDBsum:   2HFD
- ProteinModelPortal:   P19931
- SMR:   P19931
- DIP:   DIP-9961N
- STRING:   P19931
- EnsemblBacteria:   EBESCT00000000448
- EnsemblBacteria:   EBESCT00000014503
- GeneID:   945573
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0958
- KEGG:   eco:b0976
- EchoBASE:   EB0467
- EcoGene:   EG10472
- eggNOG:   NOG11979
- GeneTree:   EBGT00050000009494
- HOGENOM:   HBG468106
- OMA:   TPISESR
- ProtClustDB:   PRK11509
- BioCyc:   EcoCyc:EG10472-MONOMER
- Genevestigator:   P19931
- InterPro:   IPR010893
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF07449 HyaE; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 14890; Mature: 14759

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSDPKRTPEVSDNPVMIGE
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHH
LLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTGGNYRGVLNGIHPWAELINLM
HHHHCCCCEEEEEECCCHHHHHHHHHCCCEECCEEEEEECCCCCCHHCCCCHHHHHHHHH
RGLVEPQQERAS
HHHCCCHHHHCC
>Mature Secondary Structure 
SNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSDPKRTPEVSDNPVMIGE
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHH
LLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTGGNYRGVLNGIHPWAELINLM
HHHHCCCCEEEEEECCCHHHHHHHHHCCCEECCEEEEEECCCCCCHHCCCCHHHHHHHHH
RGLVEPQQERAS
HHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180913; 8905232; 9278503