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The map label for this gene is ycbR [H]

Identifier: 157160460

GI number: 157160460

Start: 1060105

End: 1060806

Strand: Direct

Name: ycbR [H]

Synonym: EcHS_A1048

Alternate gene names: 157160460

Gene position: 1060105-1060806 (Clockwise)

Preceding gene: 157160454

Following gene: 157160461

Centisome position: 22.83

GC content: 45.16

Gene sequence:

>702_bases
ATGAAAACTTGCATAACAAAGGGAATTGTGACCGTAAGTTTAACGGCAATATTACTCAGCTGCTCATCCGCATGGGCGGC
AGGTAAAGGCGGGATTGGACTTGCAGCAACACGTCTTGTTTATTCAGAAGGTGAAGAGCAAATTTCACTGGGTGTACGTA
ACACCAGTCCGGATGTTTCTTATCTTATTCAGTCATGGGTGATGACCCCAGATAATAAAAAATCAGCAGACTTTATTATT
ACACCACCGCTATTTGTGCTGAATCCGGCAAATGAGAATCTGTTACGCATTATGTACATTGGAGCGCCGTTGGCGAAAGA
CAGAGAAACCCTTTTCTTCACTAGCGTACGGGCAGTCCCTTCAACAACGAAGCGGGAAGAGGGAAATACCCTGAAGATTG
CCACACAAAGCGTCATCAAACTTTTCTGGCGACCAAAAGGTTTAGCGTATCCCTTAGCCGAGGCTCCGGCGAAACTGCGT
TGCACTTCGTCAGCTGACATGGTTACGGTCAGTAACCCAACACCTTATTTCATTACCCTGACAGACCTGAAAATAGGTGG
AAAGGTAGTTAAAAATCAAATGATTTCCCCCTTTGATAAATACCAATTCTCTCTGCCAAAGGGTGCCAAAAATAGCAGCG
TAACGTATCGAACCATCAATGACTACGGGGCGGAAACGCCGCAACTCAACTGTAAATCGTAA

Upstream 100 bases:

>100_bases
CATATTAACTATTATTAATAGAACTCATTAATTGTTTTATTAATTAGTACCCCTCCAGTGTTCTGGAGGGGATATTCATA
TTTTTTAAGAGTGACTATTT

Downstream 100 bases:

>100_bases
TTCGTCTTCAGTTAAGAGAGCGAGATGTATAGAACTCACCGACAACACAGCCTGTTAAGCTCTGGTGGAGTGCCATCGTT
TATTGGTGGGCTGGTGGTGT

Product: periplasmic pilus chaperone family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEGEEQISLGVRNTSPDVSYLIQSWVMTPDNKKSADFII
TPPLFVLNPANENLLRIMYIGAPLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLAEAPAKLR
CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS

Sequences:

>Translated_233_residues
MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEGEEQISLGVRNTSPDVSYLIQSWVMTPDNKKSADFII
TPPLFVLNPANENLLRIMYIGAPLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLAEAPAKLR
CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS
>Mature_233_residues
MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEGEEQISLGVRNTSPDVSYLIQSWVMTPDNKKSADFII
TPPLFVLNPANENLLRIMYIGAPLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLAEAPAKLR
CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS

Specific function: Could be required for the biogenesis of the putative ycbQ fimbria [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1787171, Length=233, Percent_Identity=98.7124463519313, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1790771, Length=224, Percent_Identity=43.3035714285714, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1786743, Length=207, Percent_Identity=41.0628019323672, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1789532, Length=219, Percent_Identity=33.7899543378995, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082203, Length=246, Percent_Identity=31.3008130081301, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788677, Length=203, Percent_Identity=34.9753694581281, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87081806, Length=205, Percent_Identity=34.6341463414634, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786936, Length=236, Percent_Identity=31.3559322033898, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786333, Length=227, Percent_Identity=28.1938325991189, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788428, Length=227, Percent_Identity=25.9911894273128, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 25394; Mature: 25394

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEGEEQISLGVRNTSPDVS
CCCHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEHHCCCCEEEEEECCCCCHHH
YLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGAPLAKDRETLFFTSVRAVP
HHHHHHCCCCCCCCCCCEEECCCEEEECCCCCCEEEEEEECCCCCCCCCEEEEEEEECCC
STTKREEGNTLKIATQSVIKLFWRPKGLAYPLAEAPAKLRCTSSADMVTVSNPTPYFITL
CCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHCCCCEEEECCCCCEEEECCCCCEEEEE
TDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS
EEEECCCHHHHHHHCCCHHHEEEECCCCCCCCCEEEEEEHHCCCCCCCCCCCC
>Mature Secondary Structure
MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEGEEQISLGVRNTSPDVS
CCCHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEHHCCCCEEEEEECCCCCHHH
YLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGAPLAKDRETLFFTSVRAVP
HHHHHHCCCCCCCCCCCEEECCCEEEECCCCCCEEEEEEECCCCCCCCCEEEEEEEECCC
STTKREEGNTLKIATQSVIKLFWRPKGLAYPLAEAPAKLRCTSSADMVTVSNPTPYFITL
CCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHCCCCEEEECCCCCEEEECCCCCEEEEE
TDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS
EEEECCCHHHHHHHCCCHHHEEEECCCCCCCCCEEEEEEHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]