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The map label for this gene is sfmH [H]

Identifier: 157160057

GI number: 157160057

Start: 621850

End: 622857

Strand: Direct

Name: sfmH [H]

Synonym: EcHS_A0608

Alternate gene names: 157160057

Gene position: 621850-622857 (Clockwise)

Preceding gene: 157160056

Following gene: 157160058

Centisome position: 13.39

GC content: 44.74

Gene sequence:

>1008_bases
ATGAAGATAATCTGCAGATTATTATTGGCGATGGCATGTTTGTGGTTAACAAACATATCCTGGGCTACTGTTTGTGCAAA
TAGTACTGGCGTAGCAGAAGATGAACACTATGATCTCTCAAATGTCTTTAATAGCACCAATAACCAGCCAGGGCAGATTG
TTGTTTTACCGGAAAAATCCGGCTGGGTAGGTGTGTCAGCAATTTGTCCACCCGGCACGCTGGTGAATTATACATACCGT
AGTTATGTCACCAACTTTATTGTTCAGGAAACTATCGATAATTATAAATATATGCAATTATATGATTATCTATTAGGTGC
GATGAGTCTGGTTGATAGTGTTATGGATATTCAGTTCCCCCCGCAAAATTATATTCGGATGGGAACAGATCCTAACGTTT
CGCAAAACCTTCCATTCGGGGTGATGGATTCTCGTTTAATATTTCGTTTAAAGGTTATTCGTCCCTTTATTAACATAGTG
GAGATCCCCAGACAGGTGATGTTTACCGTGTATGTGACATCAACGCCTTACGATCCGTTGGTTACACCTGTTTATACCAT
TAGTTTTGGTGGCCGGGTTGAAGTACCGCAAAACTGCGAATTAAATGCCGGGCAGATTGTTGAATTTGATTTTGGTGATA
TCGGCGCATCGTTATTTAGTGCGGCAGGGCCGGGTAATCGACCTGCTGGTGTCATGCCGCAAACCAAGAGCATTGCGGTC
AAATGTACGAATGTTGCTGCGCAGGCTTATTTAACAATGCGTCTGGAAGCCAGTGCCGTTTCTGGTCAGGCGATGGTGTC
GGACAATCAGGATTTAGGTTTTATTGTCGCCGATCAGAACGATACGCCGATTACGCCTAACGATCTCAATAGCGTTATTC
CTTTCCGTCTGGATGCAGCTGCGGCAGCCAATGTCACACTTCGCGCCTGGCCTATCAGTATTACCGGTCAAAAACCGACC
GAGGGGCCGTTTAGCGCGCTGGGGTATTTACGCGTCGATTATCAATGA

Upstream 100 bases:

>100_bases
CTGCATTGCGCACTATGTATTGCCGAAGCAAAGCTTACAGCAAGCCGTCACAGTTATTTCGGCAGTTTGCACACATCCTG
GCTCATAAAGGAAATTATCA

Downstream 100 bases:

>100_bases
GGTACGGAGAATGAGAAGAGTACTCTTTAGCTGTTTCTGCGGGTTACTGTGGAGTTCCAGTGGATGGGCAGCTGACCCTT
TAGGAACGATTAATATCAAT

Product: mannose binding protein FimH-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIICRLLLAMACLWLTNISWATVCANSTGVAEDEHYDLSNVFNSTNNQPGQIVVLPEKSGWVGVSAICPPGTLVNYTYR
SYVTNFIVQETIDNYKYMQLYDYLLGAMSLVDSVMDIQFPPQNYIRMGTDPNVSQNLPFGVMDSRLIFRLKVIRPFINIV
EIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQIVEFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAV
KCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPT
EGPFSALGYLRVDYQ

Sequences:

>Translated_335_residues
MKIICRLLLAMACLWLTNISWATVCANSTGVAEDEHYDLSNVFNSTNNQPGQIVVLPEKSGWVGVSAICPPGTLVNYTYR
SYVTNFIVQETIDNYKYMQLYDYLLGAMSLVDSVMDIQFPPQNYIRMGTDPNVSQNLPFGVMDSRLIFRLKVIRPFINIV
EIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQIVEFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAV
KCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPT
EGPFSALGYLRVDYQ
>Mature_335_residues
MKIICRLLLAMACLWLTNISWATVCANSTGVAEDEHYDLSNVFNSTNNQPGQIVVLPEKSGWVGVSAICPPGTLVNYTYR
SYVTNFIVQETIDNYKYMQLYDYLLGAMSLVDSVMDIQFPPQNYIRMGTDPNVSQNLPFGVMDSRLIFRLKVIRPFINIV
EIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQIVEFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAV
KCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPT
EGPFSALGYLRVDYQ

Specific function: Involved in regulation of length and mediation of adhesion of sfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin [H]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI145693100, Length=327, Percent_Identity=98.1651376146789, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI1787173, Length=196, Percent_Identity=25.5102040816327, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36756; Mature: 36756

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIICRLLLAMACLWLTNISWATVCANSTGVAEDEHYDLSNVFNSTNNQPGQIVVLPEKS
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCC
GWVGVSAICPPGTLVNYTYRSYVTNFIVQETIDNYKYMQLYDYLLGAMSLVDSVMDIQFP
CCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PQNYIRMGTDPNVSQNLPFGVMDSRLIFRLKVIRPFINIVEIPRQVMFTVYVTSTPYDPL
CHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
VTPVYTISFGGRVEVPQNCELNAGQIVEFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAV
CCCEEEEECCCEECCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
KCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAA
EEECCEEEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCC
AAANVTLRAWPISITGQKPTEGPFSALGYLRVDYQ
CCCCEEEEEEEEEECCCCCCCCCHHEEEEEEEECC
>Mature Secondary Structure
MKIICRLLLAMACLWLTNISWATVCANSTGVAEDEHYDLSNVFNSTNNQPGQIVVLPEKS
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCC
GWVGVSAICPPGTLVNYTYRSYVTNFIVQETIDNYKYMQLYDYLLGAMSLVDSVMDIQFP
CCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PQNYIRMGTDPNVSQNLPFGVMDSRLIFRLKVIRPFINIVEIPRQVMFTVYVTSTPYDPL
CHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
VTPVYTISFGGRVEVPQNCELNAGQIVEFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAV
CCCEEEEECCCEECCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
KCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAA
EEECCEEEEEEEEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCC
AAANVTLRAWPISITGQKPTEGPFSALGYLRVDYQ
CCCCEEEEEEEEEECCCCCCCCCHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]