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The map label for this gene is fdhA [H]

Identifier: 156937889

GI number: 156937889

Start: 982103

End: 983797

Strand: Direct

Name: fdhA [H]

Synonym: Igni_1101

Alternate gene names: 156937889

Gene position: 982103-983797 (Clockwise)

Preceding gene: 156937888

Following gene: 156937891

Centisome position: 75.69

GC content: 62.24

Gene sequence:

>1695_bases
ATGCCGGTGCCTTGTCCCTTCTGCGGAGTGGGGTGCAAGCTCAAGGAGGACGGCAAGCCGTTGGGCCCGGTGTGCGGCAA
GGGGCTCGAGGCCTTCGAGTACTACAAGAACGTCTTGGAGAGGCCCCTCCTCCGGGAGGGCGACCTCTTCGTAGAGGTCA
GCTTGGAGGAGGCGGCGGAGAGGGCGGCCGAGTGGATTAGGCAGTCCAAAGCCCCCTTCTTCGCGGGCTCCGCGGAAGAC
ACAAACGAGAGCGCTTGGGCCCTCCAGAAGCTCGCGCGCTTCTTGGGGACCAACGCGGTGGACCACTGCGGGAGGGTGTG
CCACTCCTCGAGCGTGGAGGCTTACAAGCTGATCTTCGGCAAACCCGTAACTCCCTTCAAGATGAGCGATAAGCTCGAGG
AAGTCTTGGTGGTGGGCAGCGACGTCAGCGTGACTTACCCGGTCTTCTGGGGCAAGATAAAGAGGGAGGCCAAGAGGGTT
GTGGTAGTGGACGCTTGGAAGAGCTTCACCATGCTTCAAGCGGACGAGGGGCTCTTAGTTCCCCCGGGCCCGGGCTTCTT
GGCCTTCTCAGAGGTTATTTATTCCATAACCTATGGGAAGGACGTGCCTCGGTGGACGGAGGACTGGGTGGACGTCCGCG
AGGTGAAGGAGATCTGGAACTCCTTCGAGAGGCCCTCCTTGGTCCACGGCATGGGCGTGACCCAGTCCGGCTACGGCTAC
CAAGCGACGGCGCGCTTGATCTTGGCCACCTTGAAGAGGGGAGGGACCGTCGCCACCCTCAGGGGGAAGGTGAACGTCCA
AGGGGCGGGGGACATGGGCCTCAACCCCTACCCCCCAGCCCCCAGAGAGGCCTTGGAGGAGGCTTGGGGCTTCCCGGTCC
CCGCCGAAAGGGGGCCCGACCTCGTGGAGGCGTTCAAGGAGCCGAGGGACTTCTACTTGGTCCACTGCCAGAACGTGGTG
GCCTCCCTCCCCAACTCTTTCGCCGTGGGGGAAGCGTTGGAGAACGCGAAGGTGATCCACGTAACTCCGAAGTTTACAGA
GACCAGCGTGTTCGCGGACATGATAGTGCCCTCCAGCCCGGTGATCTTCACCACCGGGACGGTCACCTCCGGGGACGGCT
TGGTGACCGCGGTGAGGACCAGTACCAACAGAGCTTACGAGTTCTTCAGGTTGGTGGCAGAGTACTTGGGCTTGTACCTT
CCTAAGGACGTAAAGGAAGTTACTGAAGAAGCCTTCAGCTTGGTAGACCACTACAAGAAGATAGACGTGAAGCGGCTCTA
CGCCGGGGAGGACCAGTACGTGGAGAAGCCCGAGGGGTGGAGGGAGGTCGACCCGCCGGAGGCCAAGCTCTTGGACTACC
ACTTGAAGGAGGGCTACTGGTTCTACACCGCCAGGGACCCGGCGCTCTGGACGACCAAAGGGGGGACTAAGATGATGAAG
AGGCACGCAATGAAGGAGGCGTTCTACTTCGGGGAGGACCCCGGGTGCGAGGCGGTGGAGGTCTGCTCCGAGGAGACCGG
CCGCTGCGTCGAGGGGGAGGTCCGGGTCAGCGAGAGGGTTCCCAAAGGCATGGTCCTCGCGTTCTTCAACCACCTAGGCC
TGAAGGTAAACGCCGTAATACCGTGGGAGCCCAGGGAGCCGACCGGGACGCCGGTCTACAAGGCCGCCAAGGTAAAGGTG
AGGTGCCTCAGATAG

Upstream 100 bases:

>100_bases
AGAACGAAGAGATGGTAATACTCTTCAACTTCAGTGGCCACGGGTTGTTAGACCTGGGCAACTACCAGAGCGTCTTGGGC
TTGTGAGGGGATGGCCCCGA

Downstream 100 bases:

>100_bases
AGCTCAAGGCTTGGTCCAAGTCGGCCTCCAAGTCCTCCACGTTTTCCAAGCCAACGCTCAACCTCAGCAAGTTGTCCTTT
ATCCCGAGCTCCTTCCTCAC

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MPVPCPFCGVGCKLKEDGKPLGPVCGKGLEAFEYYKNVLERPLLREGDLFVEVSLEEAAERAAEWIRQSKAPFFAGSAED
TNESAWALQKLARFLGTNAVDHCGRVCHSSSVEAYKLIFGKPVTPFKMSDKLEEVLVVGSDVSVTYPVFWGKIKREAKRV
VVVDAWKSFTMLQADEGLLVPPGPGFLAFSEVIYSITYGKDVPRWTEDWVDVREVKEIWNSFERPSLVHGMGVTQSGYGY
QATARLILATLKRGGTVATLRGKVNVQGAGDMGLNPYPPAPREALEEAWGFPVPAERGPDLVEAFKEPRDFYLVHCQNVV
ASLPNSFAVGEALENAKVIHVTPKFTETSVFADMIVPSSPVIFTTGTVTSGDGLVTAVRTSTNRAYEFFRLVAEYLGLYL
PKDVKEVTEEAFSLVDHYKKIDVKRLYAGEDQYVEKPEGWREVDPPEAKLLDYHLKEGYWFYTARDPALWTTKGGTKMMK
RHAMKEAFYFGEDPGCEAVEVCSEETGRCVEGEVRVSERVPKGMVLAFFNHLGLKVNAVIPWEPREPTGTPVYKAAKVKV
RCLR

Sequences:

>Translated_564_residues
MPVPCPFCGVGCKLKEDGKPLGPVCGKGLEAFEYYKNVLERPLLREGDLFVEVSLEEAAERAAEWIRQSKAPFFAGSAED
TNESAWALQKLARFLGTNAVDHCGRVCHSSSVEAYKLIFGKPVTPFKMSDKLEEVLVVGSDVSVTYPVFWGKIKREAKRV
VVVDAWKSFTMLQADEGLLVPPGPGFLAFSEVIYSITYGKDVPRWTEDWVDVREVKEIWNSFERPSLVHGMGVTQSGYGY
QATARLILATLKRGGTVATLRGKVNVQGAGDMGLNPYPPAPREALEEAWGFPVPAERGPDLVEAFKEPRDFYLVHCQNVV
ASLPNSFAVGEALENAKVIHVTPKFTETSVFADMIVPSSPVIFTTGTVTSGDGLVTAVRTSTNRAYEFFRLVAEYLGLYL
PKDVKEVTEEAFSLVDHYKKIDVKRLYAGEDQYVEKPEGWREVDPPEAKLLDYHLKEGYWFYTARDPALWTTKGGTKMMK
RHAMKEAFYFGEDPGCEAVEVCSEETGRCVEGEVRVSERVPKGMVLAFFNHLGLKVNAVIPWEPREPTGTPVYKAAKVKV
RCLR
>Mature_563_residues
PVPCPFCGVGCKLKEDGKPLGPVCGKGLEAFEYYKNVLERPLLREGDLFVEVSLEEAAERAAEWIRQSKAPFFAGSAEDT
NESAWALQKLARFLGTNAVDHCGRVCHSSSVEAYKLIFGKPVTPFKMSDKLEEVLVVGSDVSVTYPVFWGKIKREAKRVV
VVDAWKSFTMLQADEGLLVPPGPGFLAFSEVIYSITYGKDVPRWTEDWVDVREVKEIWNSFERPSLVHGMGVTQSGYGYQ
ATARLILATLKRGGTVATLRGKVNVQGAGDMGLNPYPPAPREALEEAWGFPVPAERGPDLVEAFKEPRDFYLVHCQNVVA
SLPNSFAVGEALENAKVIHVTPKFTETSVFADMIVPSSPVIFTTGTVTSGDGLVTAVRTSTNRAYEFFRLVAEYLGLYLP
KDVKEVTEEAFSLVDHYKKIDVKRLYAGEDQYVEKPEGWREVDPPEAKLLDYHLKEGYWFYTARDPALWTTKGGTKMMKR
HAMKEAFYFGEDPGCEAVEVCSEETGRCVEGEVRVSERVPKGMVLAFFNHLGLKVNAVIPWEPREPTGTPVYKAAKVKVR
CLR

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 62799; Mature: 62668

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPCPFCGVGCKLKEDGKPLGPVCGKGLEAFEYYKNVLERPLLREGDLFVEVSLEEAAE
CCCCCCCCCCCCEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHH
RAAEWIRQSKAPFFAGSAEDTNESAWALQKLARFLGTNAVDHCGRVCHSSSVEAYKLIFG
HHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEHEEC
KPVTPFKMSDKLEEVLVVGSDVSVTYPVFWGKIKREAKRVVVVDAWKSFTMLQADEGLLV
CCCCCCCHHHHHHHHEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCCEEEEECCCCEEE
PPGPGFLAFSEVIYSITYGKDVPRWTEDWVDVREVKEIWNSFERPSLVHGMGVTQSGYGY
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCH
QATARLILATLKRGGTVATLRGKVNVQGAGDMGLNPYPPAPREALEEAWGFPVPAERGPD
HHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCH
LVEAFKEPRDFYLVHCQNVVASLPNSFAVGEALENAKVIHVTPKFTETSVFADMIVPSSP
HHHHHHCCCCEEEEEHHHHHHHCCCCHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCC
VIFTTGTVTSGDGLVTAVRTSTNRAYEFFRLVAEYLGLYLPKDVKEVTEEAFSLVDHYKK
EEEEECCEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IDVKRLYAGEDQYVEKPEGWREVDPPEAKLLDYHLKEGYWFYTARDPALWTTKGGTKMMK
CCHHHEECCCCHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCEEEECCCHHHHH
RHAMKEAFYFGEDPGCEAVEVCSEETGRCVEGEVRVSERVPKGMVLAFFNHLGLKVNAVI
HHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCCEEHHHCCCCHHHHHHHHHCCEEEEEEE
PWEPREPTGTPVYKAAKVKVRCLR
CCCCCCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
PVPCPFCGVGCKLKEDGKPLGPVCGKGLEAFEYYKNVLERPLLREGDLFVEVSLEEAAE
CCCCCCCCCCCEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHH
RAAEWIRQSKAPFFAGSAEDTNESAWALQKLARFLGTNAVDHCGRVCHSSSVEAYKLIFG
HHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEHEEC
KPVTPFKMSDKLEEVLVVGSDVSVTYPVFWGKIKREAKRVVVVDAWKSFTMLQADEGLLV
CCCCCCCHHHHHHHHEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCCEEEEECCCCEEE
PPGPGFLAFSEVIYSITYGKDVPRWTEDWVDVREVKEIWNSFERPSLVHGMGVTQSGYGY
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCH
QATARLILATLKRGGTVATLRGKVNVQGAGDMGLNPYPPAPREALEEAWGFPVPAERGPD
HHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCH
LVEAFKEPRDFYLVHCQNVVASLPNSFAVGEALENAKVIHVTPKFTETSVFADMIVPSSP
HHHHHHCCCCEEEEEHHHHHHHCCCCHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCC
VIFTTGTVTSGDGLVTAVRTSTNRAYEFFRLVAEYLGLYLPKDVKEVTEEAFSLVDHYKK
EEEEECCEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IDVKRLYAGEDQYVEKPEGWREVDPPEAKLLDYHLKEGYWFYTARDPALWTTKGGTKMMK
CCHHHEECCCCHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCEEEECCCHHHHH
RHAMKEAFYFGEDPGCEAVEVCSEETGRCVEGEVRVSERVPKGMVLAFFNHLGLKVNAVI
HHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCCEEHHHCCCCHHHHHHHHHCCEEEEEEE
PWEPREPTGTPVYKAAKVKVRCLR
CCCCCCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]