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The map label for this gene is lacB.2

Identifier: 15675730

GI number: 15675730

Start: 1604499

End: 1605014

Strand: Reverse

Name: lacB.2

Synonym: SPy_1922

Alternate gene names: 15675730

Gene position: 1605014-1604499 (Counterclockwise)

Preceding gene: 15675731

Following gene: 15675729

Centisome position: 86.64

GC content: 36.82

Gene sequence:

>516_bases
ATGAAAATTGCTGTAGGTTGTGACCATATTGTTACTTATGAAAAAATCGCTGTTGTGGATTACCTAAAATCACAAGGTCA
TAAAGTTATTGATTGTGGTACGTATGATAATGTTCGCACACACTATCCAATTTTTGGTAAAAAAGTTGGTGAAGCAGTAG
CAAGTGGTGAAGCAGAACTAGGTGTTGTTATCTGTGGTACTGGTGTTGGTATCACAAATGCTGTAAACAAAGTTCCTGGA
ATTCGTTCAGCACTCGTTAGAGATATGACATCTGCTATCTACTCAAAAGAAGAGCTAAACGCAAACGTTATTGGTTTTGG
TGGAAAAATTATCGGTGGTTTATTGATGAATGATATTATCGATGCTTTCTTGGCCGCGGAATACAAACCAACTGAAGAAA
ATAAAAAATGGATTGAAAAAATGGATAGCTTGCAACATGCTAGCCAAGATCAAAACAACCCACACTTCTTTGATGAATTC
CTAGAAAAATGGGACCGTGGTGAATATCACGACTAA

Upstream 100 bases:

>100_bases
GTCGAAGGTAAATATGATGGTGGACGTCATCAAGTTCGTGTCGACATGCTTAATAAAATGTGCTAATTGATTGAAATAGG
TTAAAACAAGGAGAACAAAA

Downstream 100 bases:

>100_bases
TATTTGAATAAATTACTATAGGGATATATATAGAAAAAGGAGCTATTGTGATTTTAACAGTTACTTTAAATCCAGCTATT
GATGTCTCCTACCCTTTGGA

Product: galactose-6-phosphate isomerase subunit LacB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPIFGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPG
IRSALVRDMTSAIYSKEELNANVIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
LEKWDRGEYHD

Sequences:

>Translated_171_residues
MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPIFGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPG
IRSALVRDMTSAIYSKEELNANVIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
LEKWDRGEYHD
>Mature_171_residues
MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPIFGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPG
IRSALVRDMTSAIYSKEELNANVIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
LEKWDRGEYHD

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family

Homologues:

Organism=Escherichia coli, GI1790528, Length=145, Percent_Identity=39.3103448275862, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACB2_STRP1 (Q99Y13)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269904.1
- RefSeq:   YP_283000.1
- ProteinModelPortal:   Q99Y13
- SMR:   Q99Y13
- EnsemblBacteria:   EBSTRT00000000372
- EnsemblBacteria:   EBSTRT00000028802
- GeneID:   3571269
- GeneID:   901606
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1922
- KEGG:   spz:M5005_Spy_1637
- GeneTree:   EBGT00050000027286
- HOGENOM:   HBG636953
- OMA:   GHEIIDC
- ProtClustDB:   PRK08622
- BioCyc:   SPYO160490:SPY1922-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1637-MONOMER
- HAMAP:   MF_01556
- InterPro:   IPR004784
- InterPro:   IPR003500
- Gene3D:   G3DSA:3.40.1400.10
- PIRSF:   PIRSF005384
- TIGRFAMs:   TIGR00689

Pfam domain/function: PF02502 LacAB_rpiB; SSF89623 Rib/Gal_isomrase

EC number: =5.3.1.26

Molecular weight: Translated: 18894; Mature: 18894

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPIFGKKVGEAVASGEAEL
CEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCE
GVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNANVIGFGGKIIGGLLMNDII
EEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHH
DAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEFLEKWDRGEYHD
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPIFGKKVGEAVASGEAEL
CEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCE
GVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNANVIGFGGKIIGGLLMNDII
EEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHH
DAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEFLEKWDRGEYHD
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296