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The map label for this gene is lacC.2

Identifier: 15675729

GI number: 15675729

Start: 1603522

End: 1604451

Strand: Reverse

Name: lacC.2

Synonym: SPy_1921

Alternate gene names: 15675729

Gene position: 1604451-1603522 (Counterclockwise)

Preceding gene: 15675730

Following gene: 15675728

Centisome position: 86.61

GC content: 36.24

Gene sequence:

>930_bases
GTGATTTTAACAGTTACTTTAAATCCAGCTATTGATGTCTCCTACCCTTTGGATGAGCTAAAATGCGATACTGTCAATCG
AGTTGTAGACGTTACAAAGACACCCGGTGGTAAAGGCTTGAATGTTTCCCGAGTTCTTAATGAATTCGGTGAGACAGTCA
AAGCTACAGGTTGTGTAGGTGGAGAAAGCGGTGATTTTATCATTAATCATCTTCCTGATTCGATTTTAAGTCGCTTCTAT
AAAATTTCAGGTGATACTAGAACTTGTATAGCCATTTTACACGAAGGTAATCAAACGGAGATTTTAGAAAAAGGACCGAT
GTTAAGTGTAGATGAAATTGATGGATTTACTCATCATTTTAAGTATTTACTGAATGATGTTGACGTAGTGACGCTCTCAG
GCAGTTTGCCTGCTGGTATGCCAGATGATTACTATCAGAAGTTAATCAAGATTGCCAATCTTAATGGTAAGAAAACGGTT
CTGGATTGTTCTGGAAATGCTCTAGAAGCAGTACTAAAAGGTGATAGTAAACCAACAGTTATCAAACCTAATCTTGAAGA
ACTTTCTCAACTTCTAGGTAAAGAAATGACAAAAGATTTTGATGCCTTAAAAGAAGTCTTACAAGATGAACTATTTGATG
GAATTGAATGGATAATCGTTTCTCTTGGTGCTGATGGTGTATTTGCAAAGCACAAGGATACGTTTTATAACGTTGACATT
CCTAAAATCAAAATTGTAAGCGCTGTAGGTTCAGGGGATTCTACAGTGGCAGGTATTGCTTCAGGTTTAGCGAATGATGA
AGATGATCGAGCTTTATTAACAAAAGCAAATGTCTTAGGGATGTTAAATGCGCAAGAAAAAACAACTGGGCATGTTAACA
TGGCAAATTACGATAAGTTATATCAATCTATTAAAGTCAAAGAGGTATAA

Upstream 100 bases:

>100_bases
ACTTCTTTGATGAATTCCTAGAAAAATGGGACCGTGGTGAATATCACGACTAATATTTGAATAAATTACTATAGGGATAT
ATATAGAAAAAGGAGCTATT

Downstream 100 bases:

>100_bases
AAAATGACAATTACTTTAACTGAAAACAAACGCAAAAGCATGGAAAAACTAAGTGTAGATGGTGTTATTTCTGCCTTAGC
TTTTGACCAACGTGGAGCTC

Product: tagatose-6-phosphate kinase

Products: NA

Alternate protein names: Phosphotagatokinase

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSRVLNEFGETVKATGCVGGESGDFIINHLPDSILSRFY
KISGDTRTCIAILHEGNQTEILEKGPMLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTV
LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFDALKEVLQDELFDGIEWIIVSLGADGVFAKHKDTFYNVDI
PKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV

Sequences:

>Translated_309_residues
MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSRVLNEFGETVKATGCVGGESGDFIINHLPDSILSRFY
KISGDTRTCIAILHEGNQTEILEKGPMLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTV
LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFDALKEVLQDELFDGIEWIIVSLGADGVFAKHKDTFYNVDI
PKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV
>Mature_309_residues
MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSRVLNEFGETVKATGCVGGESGDFIINHLPDSILSRFY
KISGDTRTCIAILHEGNQTEILEKGPMLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTV
LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFDALKEVLQDELFDGIEWIIVSLGADGVFAKHKDTFYNVDI
PKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family. LacC subfamily

Homologues:

Organism=Escherichia coli, GI1788493, Length=276, Percent_Identity=28.9855072463768, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788017, Length=276, Percent_Identity=29.3478260869565, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACC_STRP1 (Q99Y14)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269903.1
- RefSeq:   YP_282999.1
- ProteinModelPortal:   Q99Y14
- SMR:   Q99Y14
- EnsemblBacteria:   EBSTRT00000000249
- EnsemblBacteria:   EBSTRT00000028657
- GeneID:   3571268
- GeneID:   901604
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1921
- KEGG:   spz:M5005_Spy_1636
- GeneTree:   EBGT00050000027718
- HOGENOM:   HBG670529
- OMA:   AIKPNNE
- ProtClustDB:   PRK13508
- BioCyc:   SPYO160490:SPY1921-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1636-MONOMER
- HAMAP:   MF_01557
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR005926
- InterPro:   IPR017583
- TIGRFAMs:   TIGR03168
- TIGRFAMs:   TIGR01231

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.144

Molecular weight: Translated: 33491; Mature: 33491

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSRVLNEFGETVKATGCVG
CEEEEEECCCEECCCCHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHEEEECCC
GESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEILEKGPMLSVDEIDGFTHHF
CCCCCEEEECCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHCCCCCCHHHHCCHHHHH
KYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTVLDCSGNALEAVLKGDSKPTV
HHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCCE
IKPNLEELSQLLGKEMTKDFDALKEVLQDELFDGIEWIIVSLGADGVFAKHKDTFYNVDI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCCEEECCC
PKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKL
CCEEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHEECCCCCCCCCCEECHHHHHH
YQSIKVKEV
HHHHCCCCC
>Mature Secondary Structure
MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSRVLNEFGETVKATGCVG
CEEEEEECCCEECCCCHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHEEEECCC
GESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEILEKGPMLSVDEIDGFTHHF
CCCCCEEEECCCHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHCCCCCCHHHHCCHHHHH
KYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTVLDCSGNALEAVLKGDSKPTV
HHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCCE
IKPNLEELSQLLGKEMTKDFDALKEVLQDELFDGIEWIIVSLGADGVFAKHKDTFYNVDI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCCEEECCC
PKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKL
CCEEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHEECCCCCCCCCCEECHHHHHH
YQSIKVKEV
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296