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The map label for this gene is lacA.2

Identifier: 15675731

GI number: 15675731

Start: 1605049

End: 1605477

Strand: Reverse

Name: lacA.2

Synonym: SPy_1923

Alternate gene names: 15675731

Gene position: 1605477-1605049 (Counterclockwise)

Preceding gene: 15675735

Following gene: 15675730

Centisome position: 86.67

GC content: 38.0

Gene sequence:

>429_bases
ATGGCAATTATTATCGGTGCTGACAAAGCAGGTCAAGAACTTAAAGAAGTTATCAAAGATTACCTTAAAGAAGGTAAATA
CGAAGTCGTTGATGTTAGTGAAAACGAAGTACGTGACTTTGTAGATACAACTTTAGCTGTTGTAAAAGAAGTTAATGCAT
CCGATGATAACTTAGGTATTGTCATTGATGCATATGGTGTTGGTTCTTTCATGGTAGCTACTAAAATCAAAGGAATGGTG
GCAGCTGAAGTATCAGATGAGCGCTCAGCATACATGACAAGAGGACACAACAATGCTCGAATCATCACGCTTGGTTCTGA
AATTAGTGCTCCAGGAATTGCAAAGAACATTATCAAAGGCTTTGTCGAAGGTAAATATGATGGTGGACGTCATCAAGTTC
GTGTCGACATGCTTAATAAAATGTGCTAA

Upstream 100 bases:

>100_bases
AAATAATGAAAGCGTTATTTCAAAAGATGTTGCAAATCGTTAATTAACTATCTACGTAGGTTTTCCACATTTACTTATTC
TAAATCATAGGAGAAATAAA

Downstream 100 bases:

>100_bases
TTGATTGAAATAGGTTAAAACAAGGAGAACAAAAATGAAAATTGCTGTAGGTTGTGACCATATTGTTACTTATGAAAAAA
TCGCTGTTGTGGATTACCTA

Product: galactose-6-phosphate isomerase subunit LacA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTTLAVVKEVNASDDNLGIVIDAYGVGSFMVATKIKGMV
AAEVSDERSAYMTRGHNNARIITLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC

Sequences:

>Translated_142_residues
MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTTLAVVKEVNASDDNLGIVIDAYGVGSFMVATKIKGMV
AAEVSDERSAYMTRGHNNARIITLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC
>Mature_141_residues
AIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTTLAVVKEVNASDDNLGIVIDAYGVGSFMVATKIKGMVA
AEVSDERSAYMTRGHNNARIITLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family

Homologues:

Organism=Escherichia coli, GI1790528, Length=141, Percent_Identity=31.9148936170213, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LACA2_STRP1 (Q99Y12)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269905.1
- RefSeq:   YP_283001.1
- ProteinModelPortal:   Q99Y12
- SMR:   Q99Y12
- EnsemblBacteria:   EBSTRT00000000027
- EnsemblBacteria:   EBSTRT00000028089
- GeneID:   3571231
- GeneID:   901607
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1923
- KEGG:   spz:M5005_Spy_1638
- GeneTree:   EBGT00050000027285
- HOGENOM:   HBG636953
- OMA:   ARMITVG
- ProtClustDB:   PRK08621
- BioCyc:   SPYO160490:SPY1923-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1638-MONOMER
- HAMAP:   MF_01555
- InterPro:   IPR004783
- InterPro:   IPR003500
- Gene3D:   G3DSA:3.40.1400.10
- PIRSF:   PIRSF005384
- TIGRFAMs:   TIGR01118
- TIGRFAMs:   TIGR00689

Pfam domain/function: PF02502 LacAB_rpiB; SSF89623 Rib/Gal_isomrase

EC number: =5.3.1.26

Molecular weight: Translated: 15427; Mature: 15296

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTTLAVVKEVNASDDNLGI
CEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEE
VIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARIITLGSEISAPGIAKNIIKG
EEECCCCCHHHHHHHHCCEEEECCCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
FVEGKYDGGRHQVRVDMLNKMC
HHCCCCCCCCCEEEHHHHHCCC
>Mature Secondary Structure 
AIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTTLAVVKEVNASDDNLGI
EEEEECCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEE
VIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARIITLGSEISAPGIAKNIIKG
EEECCCCCHHHHHHHHCCEEEECCCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
FVEGKYDGGRHQVRVDMLNKMC
HHCCCCCCCCCEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296