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The map label for this gene is folQ

Identifier: 15675082

GI number: 15675082

Start: 899420

End: 899779

Strand: Direct

Name: folQ

Synonym: SPy_1099

Alternate gene names: 15675082

Gene position: 899420-899779 (Clockwise)

Preceding gene: 15675081

Following gene: 15675083

Centisome position: 48.55

GC content: 40.83

Gene sequence:

>360_bases
ATGGATAAAATCGTATTAGAAGGTTGCCGTTTTTATGGCTACCATGGAGCCTTTAAAGAAGAACAGACCCTTGGGCAAAT
TTTTCTGGTTGATTTAGAATTGTCAGTCGATTTGCAAGCAGCTTCTTTGTCAGACCAATTAACAGATACGGTCCATTACG
GGATGGTGTTTGATAGTGTCCGTCAGTTAGTGGAAGGGGAAAAGTTTATTTTGATTGAACGTTTAGCAGGTGCGATTTGT
GAACAGCTTTTTAACGAATTTCCGCCTATTGAAGCCATCAAAGTGGCCATTAAAAAGGAAAACCCACCGATTGCAGGCCA
CTATAAGGCAGTTGGTATTGAATTGGAGAGACAGAGATGA

Upstream 100 bases:

>100_bases
TGCTTATGCCCTTGGAAAAGGCTGTCAGATTGTACGCGTACACGATGTCAAGGCTAATCAAGACATTGTGGCTGTGTTGA
GCCAGTTGATGTGAGGACTT

Downstream 100 bases:

>100_bases
CCATTGTTTATTTAAGTTTAGGCACCAATATGGGGGACCGAGCAGCTTACTTGCAAAAAGCTCTTGAGGCTTTAGCTGAC
TTACCTCAAACACGGTTGCT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAIC
EQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR

Sequences:

>Translated_119_residues
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAIC
EQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR
>Mature_119_residues
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAIC
EQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FOLB_STRP1 (P0C0G5)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269256.1
- RefSeq:   YP_282186.1
- ProteinModelPortal:   P0C0G5
- SMR:   P0C0G5
- EnsemblBacteria:   EBSTRT00000001479
- EnsemblBacteria:   EBSTRT00000027926
- GeneID:   3572071
- GeneID:   901220
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1099
- KEGG:   spz:M5005_Spy_0823
- GeneTree:   EBGT00050000027513
- HOGENOM:   HBG635896
- OMA:   HAPIAAI
- ProtClustDB:   CLSK797491
- BioCyc:   SPYO160490:SPY1099-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0823-MONOMER
- InterPro:   IPR006156
- InterPro:   IPR006157
- PANTHER:   PTHR20941:SF3
- SMART:   SM00905
- TIGRFAMs:   TIGR00525
- TIGRFAMs:   TIGR00526

Pfam domain/function: PF02152 FolB

EC number: =4.1.2.25

Molecular weight: Translated: 13442; Mature: 13442

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSV
CCCEEEECHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHH
RQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR
HHHHCCCCEEHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSV
CCCEEEECHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHH
RQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR
HHHHCCCCEEHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296