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The map label for this gene is ysjA

Identifier: 15673804

GI number: 15673804

Start: 1890081

End: 1891430

Strand: Reverse

Name: ysjA

Synonym: L73435

Alternate gene names: 15673804

Gene position: 1891430-1890081 (Counterclockwise)

Preceding gene: 15673805

Following gene: 15673801

Centisome position: 79.96

GC content: 38.3

Gene sequence:

>1350_bases
ATGGAAAATTCTACAGGCTTGAAGTCTTCTTTAAAGACTCGCCACATTGTTATGCTCTCACTTGGGGGAGCGATTGGTTC
AGGACTATTTTTAGGTTCTGGAAAAGTCATTGCACAGGCTGGGCCAAGTGTATTACTCTCATACATCTTAGCTGGACTGA
CACTTTATGTTGTCATGTATGGTGTTGGGAAAATGGTCATCCATCAAGATGAACATAAGGCTGGAATGGCCGGAGTTGTT
GCTCCTTTTATTGGGGACCACTGGGCGCATTTTGCGGACTGGGTTTACTGGGCAACTTGGATGGCCGTCCTAATTGCAGA
AGAAGCAGGGGTATCAACTTTCCTTGCCATGCTAATTCCTGGAGTGCCATTATGGGTTTTCGCCCTGATTGTAGCAGTTC
TTGGAACAGCAATCAATCTCTGGTCAGTTAGAGCTTTTGCCGAAACGGAATATTGGCTTGCATTTATTAAAGTCGCTGTT
ATTTTAATTTTAATTGCACTCGGAATTTATTTATTAGTTATTAATGATGCTCATCTTGGTTTTGTTGCTGATACCGCTCA
AAAAGTATCGACTAAAAGTACAGCACCAAGCTTTGCTCCTAATGGCTTTTCAGGATTTTTAACTTCATTATTGGTTGTTA
TTTTCTCATTTGGTGGTTCTGAATTGGCAGCAATTACAGTTGCTGAAACGGAAAATCCAAAAGTAGCGATTCCGAGAGCT
ATTCGAGGTGTTTTAATTCGGATTATTAGTTTTTATGTTATTCCAATCTTTTTATTCTTGCATTTATTACCATGGAGCGA
AGTTTTAAATCCAGATGCAGCAAGTCCATTTGCTACAATTTTTGCTCGAGTAGGAATTCCACACGCTGATAAAATCGTTC
TCGTAATTATTGTTATTGCAATTTTCTCAGCGGTTAACTCAGCAATTTATGCCACTTCACGCTCACTCTATTCACGCATT
CAAGGTTCAAATTCTTATGTGGGTCAAAGATTGGGCAAATTATCTAAAAATCAAGTCCCAACGAATGCGATTTTAGTTTC
ATCATTTGTTTTGTTTATTGGTGTACTTTTGTCAGCAATTTTGGGTGATGGATTCTGGCAATTTGTGGCTGGTTCGATTT
CATTTACGATTTCAATCGTTTGGATTCTCCTTTTAGTTGCTGCTCTTGTTTTATATTTTAAACATAAAGAAGTAACGAAT
TGGTTTGTTAAATTGGCAACACTCGTTGTGCTTATCGCTTTAACGATTATCTTCATCATGCAAATTGTCACTAATCCATG
GACTTTGTCAGTCTTTGCTCTAGTGATTTGCCTCCTTTCTTACTTTACTTACCGAAAGAAAAAAGCATAA

Upstream 100 bases:

>100_bases
TTAATCGTAAAGACCGACTCCAAGCAGGGTTTTGCTAGATGAATGGAAGGGAACTTATAAAAGAAAGCTTTGCTTTCACA
CATTAGAAAAGAGGAATTTT

Downstream 100 bases:

>100_bases
TAATAAAAAACATTCATTTTAAATGAATGTTTTTCTTTTGTTTGAGCTCTAGGTATTCAATAAACTTTTCTTTGATTAAA
TCATTTTTGATAAGTGACAA

Product: amino acid permease

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MENSTGLKSSLKTRHIVMLSLGGAIGSGLFLGSGKVIAQAGPSVLLSYILAGLTLYVVMYGVGKMVIHQDEHKAGMAGVV
APFIGDHWAHFADWVYWATWMAVLIAEEAGVSTFLAMLIPGVPLWVFALIVAVLGTAINLWSVRAFAETEYWLAFIKVAV
ILILIALGIYLLVINDAHLGFVADTAQKVSTKSTAPSFAPNGFSGFLTSLLVVIFSFGGSELAAITVAETENPKVAIPRA
IRGVLIRIISFYVIPIFLFLHLLPWSEVLNPDAASPFATIFARVGIPHADKIVLVIIVIAIFSAVNSAIYATSRSLYSRI
QGSNSYVGQRLGKLSKNQVPTNAILVSSFVLFIGVLLSAILGDGFWQFVAGSISFTISIVWILLLVAALVLYFKHKEVTN
WFVKLATLVVLIALTIIFIMQIVTNPWTLSVFALVICLLSYFTYRKKKA

Sequences:

>Translated_449_residues
MENSTGLKSSLKTRHIVMLSLGGAIGSGLFLGSGKVIAQAGPSVLLSYILAGLTLYVVMYGVGKMVIHQDEHKAGMAGVV
APFIGDHWAHFADWVYWATWMAVLIAEEAGVSTFLAMLIPGVPLWVFALIVAVLGTAINLWSVRAFAETEYWLAFIKVAV
ILILIALGIYLLVINDAHLGFVADTAQKVSTKSTAPSFAPNGFSGFLTSLLVVIFSFGGSELAAITVAETENPKVAIPRA
IRGVLIRIISFYVIPIFLFLHLLPWSEVLNPDAASPFATIFARVGIPHADKIVLVIIVIAIFSAVNSAIYATSRSLYSRI
QGSNSYVGQRLGKLSKNQVPTNAILVSSFVLFIGVLLSAILGDGFWQFVAGSISFTISIVWILLLVAALVLYFKHKEVTN
WFVKLATLVVLIALTIIFIMQIVTNPWTLSVFALVICLLSYFTYRKKKA
>Mature_449_residues
MENSTGLKSSLKTRHIVMLSLGGAIGSGLFLGSGKVIAQAGPSVLLSYILAGLTLYVVMYGVGKMVIHQDEHKAGMAGVV
APFIGDHWAHFADWVYWATWMAVLIAEEAGVSTFLAMLIPGVPLWVFALIVAVLGTAINLWSVRAFAETEYWLAFIKVAV
ILILIALGIYLLVINDAHLGFVADTAQKVSTKSTAPSFAPNGFSGFLTSLLVVIFSFGGSELAAITVAETENPKVAIPRA
IRGVLIRIISFYVIPIFLFLHLLPWSEVLNPDAASPFATIFARVGIPHADKIVLVIIVIAIFSAVNSAIYATSRSLYSRI
QGSNSYVGQRLGKLSKNQVPTNAILVSSFVLFIGVLLSAILGDGFWQFVAGSISFTISIVWILLLVAALVLYFKHKEVTN
WFVKLATLVVLIALTIIFIMQIVTNPWTLSVFALVICLLSYFTYRKKKA

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786302, Length=361, Percent_Identity=35.7340720221607, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1790653, Length=353, Percent_Identity=33.4277620396601, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786789, Length=390, Percent_Identity=33.5897435897436, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI48994972, Length=407, Percent_Identity=33.6609336609337, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789017, Length=354, Percent_Identity=34.180790960452, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI87081708, Length=400, Percent_Identity=31.25, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1786602, Length=390, Percent_Identity=32.8205128205128, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI87081915, Length=404, Percent_Identity=29.2079207920792, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788480, Length=370, Percent_Identity=30.5405405405405, Blast_Score=175, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324061, Length=428, Percent_Identity=27.5700934579439, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324990, Length=372, Percent_Identity=30.6451612903226, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319824, Length=320, Percent_Identity=28.125, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320772, Length=372, Percent_Identity=29.0322580645161, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324553, Length=325, Percent_Identity=31.3846153846154, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322892, Length=329, Percent_Identity=29.483282674772, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324059, Length=375, Percent_Identity=30.1333333333333, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6319542, Length=354, Percent_Identity=27.1186440677966, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321053, Length=327, Percent_Identity=29.6636085626911, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320251, Length=366, Percent_Identity=27.5956284153005, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320717, Length=364, Percent_Identity=26.6483516483516, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321629, Length=374, Percent_Identity=28.0748663101604, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6324924, Length=364, Percent_Identity=28.021978021978, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319543, Length=340, Percent_Identity=30.5882352941176, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322967, Length=318, Percent_Identity=27.0440251572327, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319608, Length=388, Percent_Identity=24.2268041237113, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324981, Length=319, Percent_Identity=29.7805642633229, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320364, Length=281, Percent_Identity=27.7580071174377, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48656; Mature: 48656

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSTGLKSSLKTRHIVMLSLGGAIGSGLFLGSGKVIAQAGPSVLLSYILAGLTLYVVMY
CCCCCCCHHHHHHHEEEEEEECCHHHCCEEECCCCEEECCCHHHHHHHHHHHHHHHHHHH
GVGKMVIHQDEHKAGMAGVVAPFIGDHWAHFADWVYWATWMAVLIAEEAGVSTFLAMLIP
HHHHHEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GVPLWVFALIVAVLGTAINLWSVRAFAETEYWLAFIKVAVILILIALGIYLLVINDAHLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FVADTAQKVSTKSTAPSFAPNGFSGFLTSLLVVIFSFGGSELAAITVAETENPKVAIPRA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEHHHH
IRGVLIRIISFYVIPIFLFLHLLPWSEVLNPDAASPFATIFARVGIPHADKIVLVIIVIA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
IFSAVNSAIYATSRSLYSRIQGSNSYVGQRLGKLSKNQVPTNAILVSSFVLFIGVLLSAI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGDGFWQFVAGSISFTISIVWILLLVAALVLYFKHKEVTNWFVKLATLVVLIALTIIFIM
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIVTNPWTLSVFALVICLLSYFTYRKKKA
HHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENSTGLKSSLKTRHIVMLSLGGAIGSGLFLGSGKVIAQAGPSVLLSYILAGLTLYVVMY
CCCCCCCHHHHHHHEEEEEEECCHHHCCEEECCCCEEECCCHHHHHHHHHHHHHHHHHHH
GVGKMVIHQDEHKAGMAGVVAPFIGDHWAHFADWVYWATWMAVLIAEEAGVSTFLAMLIP
HHHHHEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GVPLWVFALIVAVLGTAINLWSVRAFAETEYWLAFIKVAVILILIALGIYLLVINDAHLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FVADTAQKVSTKSTAPSFAPNGFSGFLTSLLVVIFSFGGSELAAITVAETENPKVAIPRA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEHHHH
IRGVLIRIISFYVIPIFLFLHLLPWSEVLNPDAASPFATIFARVGIPHADKIVLVIIVIA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
IFSAVNSAIYATSRSLYSRIQGSNSYVGQRLGKLSKNQVPTNAILVSSFVLFIGVLLSAI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGDGFWQFVAGSISFTISIVWILLLVAALVLYFKHKEVTNWFVKLATLVVLIALTIIFIM
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIVTNPWTLSVFALVICLLSYFTYRKKKA
HHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]