BacMap

Definition	Lactococcus lactis subsp. lactis Il1403, complete genome.
Accession	NC_002662
Length	2,365,589

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The map label for this gene is yphC

Identifier: 15673511

GI number: 15673511

Start: 1573215

End: 1574060

Strand: Reverse

Name: yphC

Synonym: L172964

Alternate gene names: 15673511

Gene position: 1574060-1573215 (Counterclockwise)

Preceding gene: 15673512

Following gene: 15673510

Centisome position: 66.54

GC content: 38.42

Gene sequence:

>846_bases
ATGAAAAAAGATGAAGTATGGCTTGTTACTGGAAGTTCAACGGGTTTTGGTAGAGCTTTGGTTGAAGAATTAATTGCTCA
AGACTATAAAGTAGTTGCTACTGCTCGGCAATTATCAACTTTGTCAGAGCTTCCTGACAAAGAAAATATTTTAAAAATAA
GTCTTGATGTGACGAAAGGAGATTCTATTCAAAAAGCTGTTGCTGAAACAATCGCTAAGTTTGGACGAATCGATGTTCTG
GTTAACAATGCAGGATTTGGCTATTTTGGTGTCATGGAAGAATCTGATCAATCAGCAGTGCGTAAGATCATGGACACAAA
CTTCTGGGGAGCGAATGATATGACCTTAGCGGTTCTACCATATATGCGTAAACAAAAATCGGGGCATATTCTAAATACGG
TATCCCGTGGTGGACTGACAACAACCGAAAACCTTTCTTATTATCATGCTACAAAATTTGCTATGGAGGGACTTTTTCAA
ACGCTCCGAAAAGAAGTTGAACCTTTAGGGATTTTTGTGACAAATATTGAACCTGGTTCTTTTCGGACAGATTGGGCAGG
GCGTTCCAAAGAGAGTGCGCCAGATAAGTTTTCAGATTATGAAAAGGCGCATAAACTGCTTGAACATCTAAATTCATATT
CTGGCACTCAGGTAGGGAATCCAGCATCGGCAGCCAAAGCATTTATCAAAGTTTCCAAACTTGAAAATCCACCAATGCAC
TATCTTATGGGCAAAGATGCTTACCAACTTTCTAAACAAGTTTTTGAAGAAGCTCTTGCCGAATTTGAAAAATATAAAGA
AGATGCCAAGCATCTTGATTTTGGAGAAGAAGATTATTGGAAATGA

Upstream 100 bases:

>100_bases
GATGTCTTTTTTTACTTAAAATTAATAAAAATCATTTACTTTACACTAAAGAAACAAAGAAGTATAATTTCGTTATATTT
AATCGAAAGAGGGTTTCAAA

Downstream 100 bases:

>100_bases
TTTTTCCGAACAATTAACTTGAAAAAATTAAAAAAGTCCTATTAGGACTTTTTATTTCCAAACAATATAGATAGAATTAA
AATATAATAAAAGAATCGAT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKKDEVWLVTGSSTGFGRALVEELIAQDYKVVATARQLSTLSELPDKENILKISLDVTKGDSIQKAVAETIAKFGRIDVL
VNNAGFGYFGVMEESDQSAVRKIMDTNFWGANDMTLAVLPYMRKQKSGHILNTVSRGGLTTTENLSYYHATKFAMEGLFQ
TLRKEVEPLGIFVTNIEPGSFRTDWAGRSKESAPDKFSDYEKAHKLLEHLNSYSGTQVGNPASAAKAFIKVSKLENPPMH
YLMGKDAYQLSKQVFEEALAEFEKYKEDAKHLDFGEEDYWK

Sequences:

>Translated_281_residues
MKKDEVWLVTGSSTGFGRALVEELIAQDYKVVATARQLSTLSELPDKENILKISLDVTKGDSIQKAVAETIAKFGRIDVL
VNNAGFGYFGVMEESDQSAVRKIMDTNFWGANDMTLAVLPYMRKQKSGHILNTVSRGGLTTTENLSYYHATKFAMEGLFQ
TLRKEVEPLGIFVTNIEPGSFRTDWAGRSKESAPDKFSDYEKAHKLLEHLNSYSGTQVGNPASAAKAFIKVSKLENPPMH
YLMGKDAYQLSKQVFEEALAEFEKYKEDAKHLDFGEEDYWK
>Mature_281_residues
MKKDEVWLVTGSSTGFGRALVEELIAQDYKVVATARQLSTLSELPDKENILKISLDVTKGDSIQKAVAETIAKFGRIDVL
VNNAGFGYFGVMEESDQSAVRKIMDTNFWGANDMTLAVLPYMRKQKSGHILNTVSRGGLTTTENLSYYHATKFAMEGLFQ
TLRKEVEPLGIFVTNIEPGSFRTDWAGRSKESAPDKFSDYEKAHKLLEHLNSYSGTQVGNPASAAKAFIKVSKLENPPMH
YLMGKDAYQLSKQVFEEALAEFEKYKEDAKHLDFGEEDYWK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI223718074, Length=250, Percent_Identity=32, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI7657478, Length=252, Percent_Identity=32.1428571428571, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=32.3076923076923, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=32.2751322751323, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4503817, Length=254, Percent_Identity=27.5590551181102, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI59889578, Length=142, Percent_Identity=35.2112676056338, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI150247226, Length=196, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI22507405, Length=186, Percent_Identity=32.258064516129, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI119392083, Length=186, Percent_Identity=29.5698924731183, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40548397, Length=291, Percent_Identity=26.1168384879725, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI214010158, Length=291, Percent_Identity=26.1168384879725, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI214010156, Length=291, Percent_Identity=26.1168384879725, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI22758144, Length=291, Percent_Identity=26.1168384879725, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4504503, Length=215, Percent_Identity=31.1627906976744, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=268, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI32483357, Length=199, Percent_Identity=27.6381909547739, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI19743808, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7705855, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI19923817, Length=191, Percent_Identity=25.130890052356, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787820, Length=177, Percent_Identity=36.7231638418079, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786701, Length=194, Percent_Identity=30.9278350515464, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787335, Length=183, Percent_Identity=31.6939890710383, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082160, Length=221, Percent_Identity=24.8868778280543, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=145, Percent_Identity=35.8620689655172, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=188, Percent_Identity=30.8510638297872, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=221, Percent_Identity=29.8642533936652, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=207, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=26.5957446808511, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=196, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17570069, Length=199, Percent_Identity=27.6381909547739, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=273, Percent_Identity=24.1758241758242, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=273, Percent_Identity=24.1758241758242, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=197, Percent_Identity=30.4568527918782, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=212, Percent_Identity=28.7735849056604, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=219, Percent_Identity=30.5936073059361, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17557780, Length=192, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=170, Percent_Identity=28.2352941176471, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=189, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=221, Percent_Identity=28.5067873303167, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=213, Percent_Identity=28.6384976525822, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=197, Percent_Identity=25.3807106598985, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=214, Percent_Identity=29.4392523364486, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=217, Percent_Identity=27.1889400921659, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=220, Percent_Identity=28.6363636363636, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=32.4468085106383, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=200, Percent_Identity=27.5, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=231, Percent_Identity=25.5411255411255, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=32.6424870466321, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=31.9371727748691, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=190, Percent_Identity=29.4736842105263, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=207, Percent_Identity=29.4685990338164, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28571526, Length=216, Percent_Identity=32.4074074074074, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357041, Length=213, Percent_Identity=30.0469483568075, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=29.4736842105263, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356301, Length=198, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=32.0855614973262, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640442, Length=203, Percent_Identity=31.0344827586207, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355319, Length=188, Percent_Identity=30.8510638297872, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643142, Length=217, Percent_Identity=30.8755760368664, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=237, Percent_Identity=26.1603375527426, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648944, Length=229, Percent_Identity=29.2576419213974, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=30.4568527918782, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641388, Length=197, Percent_Identity=30.4568527918782, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651139, Length=206, Percent_Identity=28.6407766990291, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24580925, Length=198, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=30, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571387, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24663911, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364494, Length=198, Percent_Identity=28.7878787878788, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=30.6818181818182, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31520; Mature: 31520

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKDEVWLVTGSSTGFGRALVEELIAQDYKVVATARQLSTLSELPDKENILKISLDVTKG
CCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
DSIQKAVAETIAKFGRIDVLVNNAGFGYFGVMEESDQSAVRKIMDTNFWGANDMTLAVLP
CHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHH
YMRKQKSGHILNTVSRGGLTTTENLSYYHATKFAMEGLFQTLRKEVEPLGIFVTNIEPGS
HHHHCCCCCEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
FRTDWAGRSKESAPDKFSDYEKAHKLLEHLNSYSGTQVGNPASAAKAFIKVSKLENPPMH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHH
YLMGKDAYQLSKQVFEEALAEFEKYKEDAKHLDFGEEDYWK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MKKDEVWLVTGSSTGFGRALVEELIAQDYKVVATARQLSTLSELPDKENILKISLDVTKG
CCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
DSIQKAVAETIAKFGRIDVLVNNAGFGYFGVMEESDQSAVRKIMDTNFWGANDMTLAVLP
CHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHH
YMRKQKSGHILNTVSRGGLTTTENLSYYHATKFAMEGLFQTLRKEVEPLGIFVTNIEPGS
HHHHCCCCCEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
FRTDWAGRSKESAPDKFSDYEKAHKLLEHLNSYSGTQVGNPASAAKAFIKVSKLENPPMH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHH
YLMGKDAYQLSKQVFEEALAEFEKYKEDAKHLDFGEEDYWK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA