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The map label for this gene is aroH

Identifier: 15673235

GI number: 15673235

Start: 1280370

End: 1281392

Strand: Reverse

Name: aroH

Synonym: L0064

Alternate gene names: 15673235

Gene position: 1281392-1280370 (Counterclockwise)

Preceding gene: 15673236

Following gene: 15673234

Centisome position: 54.17

GC content: 35.19

Gene sequence:

>1023_bases
ATGACTTTTAAAGAACTCAGTAACAAAATTAACATTAAAGATGTAAGAGAGCTAAATCATTTAAATGATGAGCAACAAGA
AAAGAAAGAAAAACGTGATAAGGAACTTGAAGCGATAATTAAGGGTGAAGACGATAGAATCCTCTTAGTCATTGGCCCCT
GCTCATCGGATAATGAAGCTGCAGTTCTAGAATATGCTCACAGATTGTTAAAACTTCAAAAAGAAGTAGAAGATAAAATT
TTTATTGTGATGCGTGTTTATACTGCAAAACCGCGGACAAACGGAGATGGCTATAAAGGCCTCATTCACGAACCTGATGC
AGATGGACATACAGACCTTATCAATGGGATAAAAATGGTTCGTGACCTTCACTATAAAGTAATTACTGAAACTGGTCTGA
CTACAGCAGATGAGATGCTATACCCAGAAAATCTACCATTAGTTGATGACTTAGTAAGTTACTATGCAGTTGGCGCTCGC
TCAGTTGAAAATCAACAACATCGCTTTGTTGCCTCAGGAATAGATGCCCCAACAGGAATGAAAAACCCGACATCAGGGAA
TTTAAAAGTTATGTTTAATGGAATGTATGCAGCCCAACAATCTCAAGATTTTCTATTTGGGAATGCTGAAGTAGAAACAT
CAGGAAATCCATTAGCTCATGCCATCCTTCGTGGTGGACAAGATGAAAATGGTAAAAACCATCCAAATTACTATACAGAT
AATCTTCTTGAAAGTATCGAAATATACGAAAAAATGGGTTTACAAAATCCATTTATTGTTATTGATACTAATCATGATAA
CTCTGGGAAGAAGTATATGGAACAAATAAGAATTGTTCGTCAAACATTAGTCAATCGTAATTGGGATGAACAAATTCATA
AATATGTCAGAGGATTTATGATTGAATCATATCTTGAAGACGGTCGTCAAGACAAACCAGAAGTATTTGGAAAATCAATC
ACTGACCCATGTTTGGGTTGGGATAAAACAGAAGAACTTATTAATGAAATTTATAATTCGTGA

Upstream 100 bases:

>100_bases
ATTATAAAGGAGGCACATAAAAAGTAAAATAGAAAAAATTTATTGCAAGTAAAATATTATTAAGTATTTTTACTAAAAAA
CTATAGAAAAAAGGTAAAAG

Downstream 100 bases:

>100_bases
TTGTAAAATGAGAAGGGATGAGTGAGAAACTTAATAGATTATTTTCATATTCTGTTCAAATAGAAAATAAATTTTTCTAT
CAAAAGTAAAGAACCAAACC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTFKELSNKINIKDVRELNHLNDEQQEKKEKRDKELEAIIKGEDDRILLVIGPCSSDNEAAVLEYAHRLLKLQKEVEDKI
FIVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGAR
SVENQQHRFVASGIDAPTGMKNPTSGNLKVMFNGMYAAQQSQDFLFGNAEVETSGNPLAHAILRGGQDENGKNHPNYYTD
NLLESIEIYEKMGLQNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFMIESYLEDGRQDKPEVFGKSI
TDPCLGWDKTEELINEIYNS

Sequences:

>Translated_340_residues
MTFKELSNKINIKDVRELNHLNDEQQEKKEKRDKELEAIIKGEDDRILLVIGPCSSDNEAAVLEYAHRLLKLQKEVEDKI
FIVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGAR
SVENQQHRFVASGIDAPTGMKNPTSGNLKVMFNGMYAAQQSQDFLFGNAEVETSGNPLAHAILRGGQDENGKNHPNYYTD
NLLESIEIYEKMGLQNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFMIESYLEDGRQDKPEVFGKSI
TDPCLGWDKTEELINEIYNS
>Mature_339_residues
TFKELSNKINIKDVRELNHLNDEQQEKKEKRDKELEAIIKGEDDRILLVIGPCSSDNEAAVLEYAHRLLKLQKEVEDKIF
IVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGARS
VENQQHRFVASGIDAPTGMKNPTSGNLKVMFNGMYAAQQSQDFLFGNAEVETSGNPLAHAILRGGQDENGKNHPNYYTDN
LLESIEIYEKMGLQNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFMIESYLEDGRQDKPEVFGKSIT
DPCLGWDKTEELINEIYNS

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=319, Percent_Identity=40.1253918495298, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1788953, Length=328, Percent_Identity=37.8048780487805, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1787996, Length=317, Percent_Identity=36.9085173501577, Blast_Score=204, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6320240, Length=311, Percent_Identity=35.6913183279743, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6319726, Length=325, Percent_Identity=36, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38843; Mature: 38712

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFKELSNKINIKDVRELNHLNDEQQEKKEKRDKELEAIIKGEDDRILLVIGPCSSDNEA
CCHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCH
AVLEYAHRLLKLQKEVEDKIFIVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMV
HHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGARSVENQQHRFVASGIDAPTGM
HHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KNPTSGNLKVMFNGMYAAQQSQDFLFGNAEVETSGNPLAHAILRGGQDENGKNHPNYYTD
CCCCCCCEEEEEECHHHHCCCCCEEECCCEEECCCCHHHHHHHHCCCCCCCCCCCCCHHH
NLLESIEIYEKMGLQNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFM
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IESYLEDGRQDKPEVFGKSITDPCLGWDKTEELINEIYNS
HHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TFKELSNKINIKDVRELNHLNDEQQEKKEKRDKELEAIIKGEDDRILLVIGPCSSDNEA
CHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCH
AVLEYAHRLLKLQKEVEDKIFIVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMV
HHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RDLHYKVITETGLTTADEMLYPENLPLVDDLVSYYAVGARSVENQQHRFVASGIDAPTGM
HHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KNPTSGNLKVMFNGMYAAQQSQDFLFGNAEVETSGNPLAHAILRGGQDENGKNHPNYYTD
CCCCCCCEEEEEECHHHHCCCCCEEECCCEEECCCCHHHHHHHHCCCCCCCCCCCCCHHH
NLLESIEIYEKMGLQNPFIVIDTNHDNSGKKYMEQIRIVRQTLVNRNWDEQIHKYVRGFM
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IESYLEDGRQDKPEVFGKSITDPCLGWDKTEELINEIYNS
HHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9422601 [H]