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The map label for this gene is ptcA

Identifier: 15672396

GI number: 15672396

Start: 419287

End: 419637

Strand: Direct

Name: ptcA

Synonym: L19292

Alternate gene names: 15672396

Gene position: 419287-419637 (Clockwise)

Preceding gene: 15672395

Following gene: 15672397

Centisome position: 17.72

GC content: 41.03

Gene sequence:

>351_bases
ATGACTGATAAATACGAGAATCCAACAAGTGATGACTACATGGGTGTTGTAATGGGCATTATCATGAGTGGAGGAAATGC
CAAAGGTTTAGCCTTCCAAGCCATTCAACAAGCCAAAGCTGGTGAATTTGCCGAAGCTGAAAGTTCATTAAACGAAGCGA
GTGAACAACTTCGTGAAGCACATGATGTTCAGACTGACCTTTTGACACGTTTAGCTCAAGGCGAAAAAATTGGTTGGAAT
CTTTACATGGTTCATGCTCAAGACCACTTAATGAATGCGATTACCTTTAAAGACCTTGCTGTAGAAGTTGTCGGTCAAGA
ACAACGCCTGCAAGCACTTGAAAACAAATAA

Upstream 100 bases:

>100_bases
AAACTTGATGAATTAAGGTTTGAAAATTTCAAACTTGTGAAAGAGCGAAAGCTCTTTTACTATGTAAATATCTAAGCAAA
GAGAAATGGGAAGATAAGAA

Downstream 100 bases:

>100_bases
TATAGCTCCTAGCTTATTAGAAAAGCAAGATTAAAAGTTGCGGAGACGCAACTTTTTTCTAACCAAAAAGTTTAAAGAAG
AAAGGAGAGAATGATGAGTT

Product: cellobiose-specific PTS system IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MTDKYENPTSDDYMGVVMGIIMSGGNAKGLAFQAIQQAKAGEFAEAESSLNEASEQLREAHDVQTDLLTRLAQGEKIGWN
LYMVHAQDHLMNAITFKDLAVEVVGQEQRLQALENK

Sequences:

>Translated_116_residues
MTDKYENPTSDDYMGVVMGIIMSGGNAKGLAFQAIQQAKAGEFAEAESSLNEASEQLREAHDVQTDLLTRLAQGEKIGWN
LYMVHAQDHLMNAITFKDLAVEVVGQEQRLQALENK
>Mature_115_residues
TDKYENPTSDDYMGVVMGIIMSGGNAKGLAFQAIQQAKAGEFAEAESSLNEASEQLREAHDVQTDLLTRLAQGEKIGWNL
YMVHAQDHLMNAITFKDLAVEVVGQEQRLQALENK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1447

COG function: function code G; Phosphotransferase system cellobiose-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=97, Percent_Identity=41.2371134020619, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 12815; Mature: 12683

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKYENPTSDDYMGVVMGIIMSGGNAKGLAFQAIQQAKAGEFAEAESSLNEASEQLREA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HDVQTDLLTRLAQGEKIGWNLYMVHAQDHLMNAITFKDLAVEVVGQEQRLQALENK
HHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHCCC
>Mature Secondary Structure 
TDKYENPTSDDYMGVVMGIIMSGGNAKGLAFQAIQQAKAGEFAEAESSLNEASEQLREA
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HDVQTDLLTRLAQGEKIGWNLYMVHAQDHLMNAITFKDLAVEVVGQEQRLQALENK
HHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]