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The map label for this gene is 15668660

Identifier: 15668660

GI number: 15668660

Start: 424100

End: 425122

Strand: Reverse

Name: 15668660

Synonym: MJ0483

Alternate gene names: NA

Gene position: 425122-424100 (Counterclockwise)

Preceding gene: 15668663

Following gene: 15668658

Centisome position: 25.53

GC content: 27.08

Gene sequence:

>1023_bases
TTGCTCTTTAAAACTATATTTTATCAAAAACTTCAAAAAAAGGTGACTACTTTGTTCAACTTAGAAACAGAAAGAGTTAT
AAGAGAAATTGAAAATTTAAATAAAAACAATCCAAAAGTTATTTTTCAAGCTCCAGAAGGTTTAAAGCTGAAAGTTGAAA
AAGAGATTGAAAAAATTAAGCAATATTTTAAACAAAAAAATATAAACATTGAGATTTACCTATGGGGAAATACTTGCTTC
GGTGCATGTGATTTAATAGACAACCATGTTAAAAACCTAAATGTTGATTTAATCATACACTATGGACACGAAAAACTTAG
CTATGCAAATCCAGAGATTAAAACCCTCTTCATTCCCGCATATCACATATTCAATAAAGATGAAGAGGAAAAAATCTTAA
ATGATATAAAAAACTTTATAGAAAAACATAAAAGTGGAGGAAAAAAAGTTGCTATAGCAACAACCATCCAATATAAAAAA
CTTTTAAAAGATTTTAATCCAAGTATAATCTTAGGTTGTAGAGGAGAAGTTAAAGAAGGGGATGTTATATTATTTGTTGG
AACCGGAAGATTTCATCCTTTAATGATTGCTTATAAATATCAAAAGGAGGTTTTTATATACAATCCTCTCTCTAAGTGCT
TTGACAAGATATCTGAAGAAGAGATTAATAAGTTTATAAAAAAGAGAATTTTAGCAATATCTAAACTATTATTAAACAAA
CCAAAAAAGGTTGGTGTTGTTTTATCAACAAAAAAAGGACAGTGTAGGAAGAGGGTTTTTGATGAGATTATAAAACTGTT
AGAAGAAAACGATGTTAATTACCTCCCAATATTAGTTGATAATATTTCTCCAGATATTTTATTCTATGATGTTGATTGCT
ATATTATAGTTGCATGTCCAAGAATCGTTTTAGACGATTATATCTTATACAAAAAACCAATTTACACTCCAGAAGAATTT
AAACTTTTCTTGAAAAATAGCTTTAAATATAAGTTTGATGAAATTAAGGAGGATGATTTCTAA

Upstream 100 bases:

>100_bases
TTAAAACAAGGATTAAGCTAATGTCAAAAATCTTAAAAACTATTTTTATTTAAAACCTAAAATCTATACATTCAAATTAT
TAGATTATATATATTTATAG

Downstream 100 bases:

>100_bases
AATTTTATTATCTATTAACAGAATGTCCTATTTGTTGCTGGTAAGCAGAGAGTTTCACCACAATTTGGACATGTTATAAC
AACCTTGTCCTTTTCATAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLFKTIFYQKLQKKVTTLFNLETERVIREIENLNKNNPKVIFQAPEGLKLKVEKEIEKIKQYFKQKNINIEIYLWGNTCF
GACDLIDNHVKNLNVDLIIHYGHEKLSYANPEIKTLFIPAYHIFNKDEEEKILNDIKNFIEKHKSGGKKVAIATTIQYKK
LLKDFNPSIILGCRGEVKEGDVILFVGTGRFHPLMIAYKYQKEVFIYNPLSKCFDKISEEEINKFIKKRILAISKLLLNK
PKKVGVVLSTKKGQCRKRVFDEIIKLLEENDVNYLPILVDNISPDILFYDVDCYIIVACPRIVLDDYILYKKPIYTPEEF
KLFLKNSFKYKFDEIKEDDF

Sequences:

>Translated_340_residues
MLFKTIFYQKLQKKVTTLFNLETERVIREIENLNKNNPKVIFQAPEGLKLKVEKEIEKIKQYFKQKNINIEIYLWGNTCF
GACDLIDNHVKNLNVDLIIHYGHEKLSYANPEIKTLFIPAYHIFNKDEEEKILNDIKNFIEKHKSGGKKVAIATTIQYKK
LLKDFNPSIILGCRGEVKEGDVILFVGTGRFHPLMIAYKYQKEVFIYNPLSKCFDKISEEEINKFIKKRILAISKLLLNK
PKKVGVVLSTKKGQCRKRVFDEIIKLLEENDVNYLPILVDNISPDILFYDVDCYIIVACPRIVLDDYILYKKPIYTPEEF
KLFLKNSFKYKFDEIKEDDF
>Mature_340_residues
MLFKTIFYQKLQKKVTTLFNLETERVIREIENLNKNNPKVIFQAPEGLKLKVEKEIEKIKQYFKQKNINIEIYLWGNTCF
GACDLIDNHVKNLNVDLIIHYGHEKLSYANPEIKTLFIPAYHIFNKDEEEKILNDIKNFIEKHKSGGKKVAIATTIQYKK
LLKDFNPSIILGCRGEVKEGDVILFVGTGRFHPLMIAYKYQKEVFIYNPLSKCFDKISEEEINKFIKKRILAISKLLLNK
PKKVGVVLSTKKGQCRKRVFDEIIKLLEENDVNYLPILVDNISPDILFYDVDCYIIVACPRIVLDDYILYKKPIYTPEEF
KLFLKNSFKYKFDEIKEDDF

Specific function: Unknown

COG id: COG1736

COG function: function code J; Diphthamide synthase subunit DPH2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI116686106, Length=344, Percent_Identity=23.546511627907, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17552166, Length=319, Percent_Identity=26.9592476489028, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322088, Length=337, Percent_Identity=27.0029673590504, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24662841, Length=359, Percent_Identity=26.4623955431755, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356957, Length=359, Percent_Identity=26.4623955431755, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y483_METJA (Q57907)

Other databases:

- EMBL:   L77117
- PIR:   C64360
- RefSeq:   NP_247459.1
- GeneID:   1451345
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0483
- NMPDR:   fig|243232.1.peg.496
- TIGR:   MJ0483
- HOGENOM:   HBG539063
- OMA:   IIHYGHE
- ProtClustDB:   CLSK2517614
- BioCyc:   MJAN243232:MJ_0483-MONOMER
- InterPro:   IPR016435
- InterPro:   IPR002728
- InterPro:   IPR022428
- PANTHER:   PTHR10762
- PIRSF:   PIRSF004967
- TIGRFAMs:   TIGR03682
- TIGRFAMs:   TIGR00322

Pfam domain/function: PF01866 Diphthamide_syn

EC number: NA

Molecular weight: Translated: 40015; Mature: 40015

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKTIFYQKLQKKVTTLFNLETERVIREIENLNKNNPKVIFQAPEGLKLKVEKEIEKIK
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEHHHHHHHHH
QYFKQKNINIEIYLWGNTCFGACDLIDNHVKNLNVDLIIHYGHEKLSYANPEIKTLFIPA
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEEEE
YHIFNKDEEEKILNDIKNFIEKHKSGGKKVAIATTIQYKKLLKDFNPSIILGCRGEVKEG
HHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCEEEECCCCCCCC
DVILFVGTGRFHPLMIAYKYQKEVFIYNPLSKCFDKISEEEINKFIKKRILAISKLLLNK
CEEEEEECCCCCEEEEEEEECCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
PKKVGVVLSTKKGQCRKRVFDEIIKLLEENDVNYLPILVDNISPDILFYDVDCYIIVACP
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCEEEEEECC
RIVLDDYILYKKPIYTPEEFKLFLKNSFKYKFDEIKEDDF
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCCCCC
>Mature Secondary Structure
MLFKTIFYQKLQKKVTTLFNLETERVIREIENLNKNNPKVIFQAPEGLKLKVEKEIEKIK
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEHHHHHHHHH
QYFKQKNINIEIYLWGNTCFGACDLIDNHVKNLNVDLIIHYGHEKLSYANPEIKTLFIPA
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEEEE
YHIFNKDEEEKILNDIKNFIEKHKSGGKKVAIATTIQYKKLLKDFNPSIILGCRGEVKEG
HHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCEEEECCCCCCCC
DVILFVGTGRFHPLMIAYKYQKEVFIYNPLSKCFDKISEEEINKFIKKRILAISKLLLNK
CEEEEEECCCCCEEEEEEEECCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
PKKVGVVLSTKKGQCRKRVFDEIIKLLEENDVNYLPILVDNISPDILFYDVDCYIIVACP
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCEEEEEECC
RIVLDDYILYKKPIYTPEEFKLFLKNSFKYKFDEIKEDDF
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087