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The map label for this gene is hypB

Identifier: 15668618

GI number: 15668618

Start: 396327

End: 396992

Strand: Reverse

Name: hypB

Synonym: MJ0442

Alternate gene names: 15668618

Gene position: 396992-396327 (Counterclockwise)

Preceding gene: 15668619

Following gene: 15668615

Centisome position: 23.84

GC content: 33.78

Gene sequence:

>666_bases
ATGCACTTAGTAGGAGTTTTAGACATTGCCAAAGATATATTAAAAGCAAATAAAAGATTGGCTGATAAAAACAGAAAGCT
CTTAAATAAACATGGTGTTGTTGCATTTGACTTCATGGGAGCTATTGGTAGTGGAAAAACCCTACTAATTGAAAAGTTGA
TTGATAATTTAAAAGATAAGTATAAAATAGCCTGCATTGCTGGAGATGTTATAGCAAAGTTTGATGCTGAGAGAATGGAG
AAGCATGGGGCTAAGGTAGTGCCTTTAAATACGGGTAAAGAATGCCATTTAGATGCTCACTTAGTAGGGCATGCCTTGGA
GGATTTAAACTTAGATGAAATTGATTTACTGTTTATAGAGAACGTTGGAAATTTAATCTGCCCAGCTGATTTTGATTTAG
GGACTCATAAAAGGATTGTTGTGATTTCAACAACTGAAGGGGATGATACGATAGAAAAACACCCTGGCATTATGAAAACA
GCGGATTTAATAGTTATCAATAAGATTGATTTAGCAGATGCCGTTGGAGCTGACATAAAAAAGATGGAGAATGATGCTAA
AAGAATAAATCCAGATGCAGAAGTTGTTTTATTAAGTTTAAAAACAATGGAAGGGTTTGATAAGGTTTTAGAGTTTATTG
AAAAGAGTGTTAAAGAGGTTAAATAG

Upstream 100 bases:

>100_bases
TTGATGAGTTATATGAGAAGATGAATCCCAATTATGAAGAGATAGAGATTGAAGAAGATGAAGATGAAATAGAGGATGAA
GAATAAATTGGTGATGAAAT

Downstream 100 bases:

>100_bases
GACTTTCGCAGGGATAAATGTTTTATTTAAATGAAGATGCCTTTGGGCATCAAATTACCTTAATAAAATATATAAACTGC
GAAAGTCCTATTAAAGAAGC

Product: hydrogenase expression/formation protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MHLVGVLDIAKDILKANKRLADKNRKLLNKHGVVAFDFMGAIGSGKTLLIEKLIDNLKDKYKIACIAGDVIAKFDAERME
KHGAKVVPLNTGKECHLDAHLVGHALEDLNLDEIDLLFIENVGNLICPADFDLGTHKRIVVISTTEGDDTIEKHPGIMKT
ADLIVINKIDLADAVGADIKKMENDAKRINPDAEVVLLSLKTMEGFDKVLEFIEKSVKEVK

Sequences:

>Translated_221_residues
MHLVGVLDIAKDILKANKRLADKNRKLLNKHGVVAFDFMGAIGSGKTLLIEKLIDNLKDKYKIACIAGDVIAKFDAERME
KHGAKVVPLNTGKECHLDAHLVGHALEDLNLDEIDLLFIENVGNLICPADFDLGTHKRIVVISTTEGDDTIEKHPGIMKT
ADLIVINKIDLADAVGADIKKMENDAKRINPDAEVVLLSLKTMEGFDKVLEFIEKSVKEVK
>Mature_221_residues
MHLVGVLDIAKDILKANKRLADKNRKLLNKHGVVAFDFMGAIGSGKTLLIEKLIDNLKDKYKIACIAGDVIAKFDAERME
KHGAKVVPLNTGKECHLDAHLVGHALEDLNLDEIDLLFIENVGNLICPADFDLGTHKRIVVISTTEGDDTIEKHPGIMKT
ADLIVINKIDLADAVGADIKKMENDAKRINPDAEVVLLSLKTMEGFDKVLEFIEKSVKEVK

Specific function: Could be involved in nickel binding and accumulation

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family

Homologues:

Organism=Escherichia coli, GI1789082, Length=209, Percent_Identity=39.2344497607655, Blast_Score=165, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPB_METJA (Q57884)

Other databases:

- EMBL:   L77117
- PIR:   B64355
- RefSeq:   NP_247416.1
- PDB:   2HF8
- PDB:   2HF9
- PDBsum:   2HF8
- PDBsum:   2HF9
- ProteinModelPortal:   Q57884
- SMR:   Q57884
- GeneID:   1451302
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_0442
- NMPDR:   fig|243232.1.peg.453
- TIGR:   MJ0442
- HOGENOM:   HBG364734
- OMA:   RIVVIST
- ProtClustDB:   CLSK2749883
- BioCyc:   MJAN243232:MJ_0442-MONOMER
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00073

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 24341; Mature: 24341

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLVGVLDIAKDILKANKRLADKNRKLLNKHGVVAFDFMGAIGSGKTLLIEKLIDNLKDK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
YKIACIAGDVIAKFDAERMEKHGAKVVPLNTGKECHLDAHLVGHALEDLNLDEIDLLFIE
EEEEEEECHHHHHCCHHHHHHCCCEEEEECCCCCCEEHHHHHHHHHHHCCCCCEEEEEEE
NVGNLICPADFDLGTHKRIVVISTTEGDDTIEKHPGIMKTADLIVINKIDLADAVGADIK
CCCCEECCCCCCCCCCCEEEEEEECCCCCHHHHCCCCEEECCEEEEEECCHHHHHHHHHH
KMENDAKRINPDAEVVLLSLKTMEGFDKVLEFIEKSVKEVK
HHHHHHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHLVGVLDIAKDILKANKRLADKNRKLLNKHGVVAFDFMGAIGSGKTLLIEKLIDNLKDK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
YKIACIAGDVIAKFDAERMEKHGAKVVPLNTGKECHLDAHLVGHALEDLNLDEIDLLFIE
EEEEEEECHHHHHCCHHHHHHCCCEEEEECCCCCCEEHHHHHHHHHHHCCCCCEEEEEEE
NVGNLICPADFDLGTHKRIVVISTTEGDDTIEKHPGIMKTADLIVINKIDLADAVGADIK
CCCCEECCCCCCCCCCCEEEEEEECCCCCHHHHCCCCEEECCEEEEEECCHHHHHHHHHH
KMENDAKRINPDAEVVLLSLKTMEGFDKVLEFIEKSVKEVK
HHHHHHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087