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The map label for this gene is cmk

Identifier: 15607094

GI number: 15607094

Start: 1517970

End: 1518638

Strand: Direct

Name: cmk

Synonym: aq_2153

Alternate gene names: 15607094

Gene position: 1517970-1518638 (Clockwise)

Preceding gene: 15607093

Following gene: 15607095

Centisome position: 97.85

GC content: 40.66

Gene sequence:

>669_bases
ATGAAGATAGCCATAGACGGACCTTCAGCGAGCGGAAAAAGTACCGTTGCCAAAATAATCTCACAAAAATTAAACATTCC
TTACTTAGAAACTGGTTTAGTATACAGAACTTACGCCTACGTTTCACTTAAGTTCAAAGTCCCTATTCAAGACATAGATA
AACTCTTTAGTCTTCCCGTTAAAGTTGTGCCTAAAATCGGAAAGACAGAAGTTTATATTGAGGGAAAGCCGGTTAACGAA
GAAGACTTAAGGAGTGAAGAAGTAGGAAAAAGGGCATCCGAACTCGGTTCTATCCCCGAATTCAGGGAGAGAATTAATAA
ACTCTTCAAGGAGATAATAAACAACAAACAGATGGTAGTTGAGGGAAGGGACGCAGGAACTCACATAATCCCAGAAGCAC
CTGTTAAGGTTTTCATAACAGCCTCTCCTGAGGAGAGGGCAAAGAGAAGGTACGAACAACTAAAAGAGCTGGGATACGAG
GTTTCCTTTGAAGAAATACTCCAGAAAATACTGGAAAGGGATAAAAGAGACATGGAAAGACCAAAGTACCCCTTCAAGCC
TGCAGAAGATGCCGTTATTATAGATACGACCAGAAAAAGCGTTGAAGAAGTGGTCGAAGAAGTCTTAAAGATTATCCATG
AACGTTCCCAATCTGCTGAGCTTATCTAG

Upstream 100 bases:

>100_bases
AAACCGCACTCCTTTACGCAAGAAGACCTGCAGATCTCGAGCTAAGGCTGAAAGGTATATCCACCGATGAAGATATTATA
GAAGGTGATAATTACTTAAC

Downstream 100 bases:

>100_bases
ACTCATACTTTCCCCCTTAATTCTTTACTTCGTTTTAGAAGAAAATTACTTAAGTTCTTTAGTCTTAGTCCTTTTTTTAG
CTTTAATGGATTTTCTCGAC

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKIAIDGPSASGKSTVAKIISQKLNIPYLETGLVYRTYAYVSLKFKVPIQDIDKLFSLPVKVVPKIGKTEVYIEGKPVNE
EDLRSEEVGKRASELGSIPEFRERINKLFKEIINNKQMVVEGRDAGTHIIPEAPVKVFITASPEERAKRRYEQLKELGYE
VSFEEILQKILERDKRDMERPKYPFKPAEDAVIIDTTRKSVEEVVEEVLKIIHERSQSAELI

Sequences:

>Translated_222_residues
MKIAIDGPSASGKSTVAKIISQKLNIPYLETGLVYRTYAYVSLKFKVPIQDIDKLFSLPVKVVPKIGKTEVYIEGKPVNE
EDLRSEEVGKRASELGSIPEFRERINKLFKEIINNKQMVVEGRDAGTHIIPEAPVKVFITASPEERAKRRYEQLKELGYE
VSFEEILQKILERDKRDMERPKYPFKPAEDAVIIDTTRKSVEEVVEEVLKIIHERSQSAELI
>Mature_222_residues
MKIAIDGPSASGKSTVAKIISQKLNIPYLETGLVYRTYAYVSLKFKVPIQDIDKLFSLPVKVVPKIGKTEVYIEGKPVNE
EDLRSEEVGKRASELGSIPEFRERINKLFKEIINNKQMVVEGRDAGTHIIPEAPVKVFITASPEERAKRRYEQLKELGYE
VSFEEILQKILERDKRDMERPKYPFKPAEDAVIIDTTRKSVEEVVEEVLKIIHERSQSAELI

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=215, Percent_Identity=40.4651162790698, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_AQUAE (O67907)

Other databases:

- EMBL:   AE000657
- PIR:   G70484
- RefSeq:   NP_214476.1
- ProteinModelPortal:   O67907
- SMR:   O67907
- GeneID:   1193896
- GenomeReviews:   AE000657_GR
- KEGG:   aae:aq_2153
- NMPDR:   fig|224324.1.peg.1491
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- PhylomeDB:   O67907
- ProtClustDB:   CLSK2748566
- BioCyc:   AAEO224324:AQ_2153-MONOMER
- BRENDA:   2.7.4.14
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 25401; Mature: 25401

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIDGPSASGKSTVAKIISQKLNIPYLETGLVYRTYAYVSLKFKVPIQDIDKLFSLPV
CEEEECCCCCCCHHHHHHHHHHHCCCCEEHHCCEEEEEEEEEEEEECCHHHHHHHHHCCH
KVVPKIGKTEVYIEGKPVNEEDLRSEEVGKRASELGSIPEFRERINKLFKEIINNKQMVV
HHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEE
EGRDAGTHIIPEAPVKVFITASPEERAKRRYEQLKELGYEVSFEEILQKILERDKRDMER
ECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
PKYPFKPAEDAVIIDTTRKSVEEVVEEVLKIIHERSQSAELI
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKIAIDGPSASGKSTVAKIISQKLNIPYLETGLVYRTYAYVSLKFKVPIQDIDKLFSLPV
CEEEECCCCCCCHHHHHHHHHHHCCCCEEHHCCEEEEEEEEEEEEECCHHHHHHHHHCCH
KVVPKIGKTEVYIEGKPVNEEDLRSEEVGKRASELGSIPEFRERINKLFKEIINNKQMVV
HHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEE
EGRDAGTHIIPEAPVKVFITASPEERAKRRYEQLKELGYEVSFEEILQKILERDKRDMER
ECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
PKYPFKPAEDAVIIDTTRKSVEEVVEEVLKIIHERSQSAELI
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320