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The map label for this gene is ttrR [H]

Identifier: 15602590

GI number: 15602590

Start: 855863

End: 856441

Strand: Direct

Name: ttrR [H]

Synonym: PM0725

Alternate gene names: 15602590

Gene position: 855863-856441 (Clockwise)

Preceding gene: 15602589

Following gene: 15602597

Centisome position: 37.91

GC content: 38.69

Gene sequence:

>579_bases
ATGTTAATTCATCTGGTTGATGATGACTTAACCGTTTTGGATGCGGCGCGTTTTTTATTAGAACAAGCTGGCTATCAAGT
CCAAACATGGTCAAATAGCCAAGCCTTTGTGAATAAAGCACCGCTGTTTGAACCAGGTGTCGTATTACTGGATATGAAAA
TGCCATTACTTGACGGTCATCAAGTACATCAATTTTTATGCCAACAACAAAGTACGCTTGCAGTAGTGATTATGACAGCA
CATGCCGATGTGCCCATGGCGGTGCAAGAACTCAAACAAGGTGCGGTAGATTTTTTACAAAAACCTGTTCAATTTTCGCA
ATTACAATCTGTATTAAAAACCGCAATACAAACCACGCAATCACGTTACGAACGCTATAAAATTCGACATTGTTATGCCC
AGTTAAGTCGAAAAGAATTGGATATTTTGGCATTGTTAATTCAAGGCTGTATTAATCGGCAAATTGCTGAAGCCTTAAAT
ATTTCTGTGCGTACTGTGGAAGTGCATCGCTCACATATTATGGAAAAAATGCAAGCGCAAACTATTGCTGAATTGATCTA
TAAAACCGCTCAACTCTAA

Upstream 100 bases:

>100_bases
GATTAATGCGTTCGATTAATGGTGACATTTCTTTGCATAACCGCCTTGATCAACAAGGAGCGGAAGTGATTTTAAAATTA
CCAAATAAAGTGGGGGAAAC

Downstream 100 bases:

>100_bases
CAAAACAGCAGAGGTTTACCTCTGCTGAATTCGGTTAAAGCTGATTTAAATCGAGCACATCGGTCATATCAAATAGCCCC
TTTTCTTTTTGTGCAAGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLIHLVDDDLTVLDAARFLLEQAGYQVQTWSNSQAFVNKAPLFEPGVVLLDMKMPLLDGHQVHQFLCQQQSTLAVVIMTA
HADVPMAVQELKQGAVDFLQKPVQFSQLQSVLKTAIQTTQSRYERYKIRHCYAQLSRKELDILALLIQGCINRQIAEALN
ISVRTVEVHRSHIMEKMQAQTIAELIYKTAQL

Sequences:

>Translated_192_residues
MLIHLVDDDLTVLDAARFLLEQAGYQVQTWSNSQAFVNKAPLFEPGVVLLDMKMPLLDGHQVHQFLCQQQSTLAVVIMTA
HADVPMAVQELKQGAVDFLQKPVQFSQLQSVLKTAIQTTQSRYERYKIRHCYAQLSRKELDILALLIQGCINRQIAEALN
ISVRTVEVHRSHIMEKMQAQTIAELIYKTAQL
>Mature_192_residues
MLIHLVDDDLTVLDAARFLLEQAGYQVQTWSNSQAFVNKAPLFEPGVVLLDMKMPLLDGHQVHQFLCQQQSTLAVVIMTA
HADVPMAVQELKQGAVDFLQKPVQFSQLQSVLKTAIQTTQSRYERYKIRHCYAQLSRKELDILALLIQGCINRQIAEALN
ISVRTVEVHRSHIMEKMQAQTIAELIYKTAQL

Specific function: FixJ, when activated by fixL, induces the expression of both nifA, required for activation of classical nif and fix genes, and fixK, required for fixN activation [H]

COG id: COG4566

COG function: function code T; Response regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=138, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790299, Length=147, Percent_Identity=29.9319727891156, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=24.2718446601942, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=121, Percent_Identity=35.5371900826446, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21813; Mature: 21813

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIHLVDDDLTVLDAARFLLEQAGYQVQTWSNSQAFVNKAPLFEPGVVLLDMKMPLLDGH
CEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHCCCCCCCCCEEEEECCCCCCCHH
QVHQFLCQQQSTLAVVIMTAHADVPMAVQELKQGAVDFLQKPVQFSQLQSVLKTAIQTTQ
HHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SRYERYKIRHCYAQLSRKELDILALLIQGCINRQIAEALNISVRTVEVHRSHIMEKMQAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TIAELIYKTAQL
HHHHHHHHHHCC
>Mature Secondary Structure
MLIHLVDDDLTVLDAARFLLEQAGYQVQTWSNSQAFVNKAPLFEPGVVLLDMKMPLLDGH
CEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHCCCCCCCCCEEEEECCCCCCCHH
QVHQFLCQQQSTLAVVIMTAHADVPMAVQELKQGAVDFLQKPVQFSQLQSVLKTAIQTTQ
HHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SRYERYKIRHCYAQLSRKELDILALLIQGCINRQIAEALNISVRTVEVHRSHIMEKMQAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
TIAELIYKTAQL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2000090; 12597275 [H]