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The map label for this gene is pitB [C]

Identifier: 15602114

GI number: 15602114

Start: 279655

End: 280917

Strand: Reverse

Name: pitB [C]

Synonym: PM0249

Alternate gene names: 15602114

Gene position: 280917-279655 (Counterclockwise)

Preceding gene: 15602115

Following gene: 15602113

Centisome position: 12.44

GC content: 42.68

Gene sequence:

>1263_bases
ATGGAACTACTTAATCAATATGGTACTTTGCTCGTTTTTATTACGGCTGCATTTGGTTTTTTCATGGCCTTTGGTATTGG
TGCGAATGATGTATCAAATGCAATGGGCACCTCTGTTGGCTCAGGTACTATTACTGCCAAGCAAGCCATTATTATTGCAA
TGATTTTTGAATCCGCCGGGGCTTATTTGGCGGGCGGTGAAGTGACCGAAACCATTAAAAGCGGCATCATTGATCCCATG
AAATTTGTGGACACACCAGATATTTTAGTCTTAGGGATGATGGCGGCGCTATTTGCTTCTGGATTATGGTTATTAATTGC
TTCACGCATGGGTTGGCCTGTATCTACTACGCATTCGATTGTCGGTGCGGTGGTTGGCTTTGCTTGCGTCACCGTGGGTA
AAGAGGCTGTAGAATGGAGTACAATTAAAAACATTGTCGGCAGTTGGTTTATCACACCGGTTATTGCGGGCATTGTCGCT
TACGGTATTTTTGCCAGCACGCAAAAATTGATTTTCGATACTGATGAACCCTTAAAAAATGCGCAAAAATATGGTCCTTA
CTACATGGGGATCACCGCCTTTATTCTATGTATTGTGACATTAACGAAAGGGCTAAAACACATTGGTTTACATTTAAATG
GCTTTGAAGTCTTTCTGATTTCATTACTGATTGGCATTATTTCTATCGTGGTGTGCTATTTTTATTTCAGAAGCCCAAAT
TTCATCCAAAAAGTACAACGTGGTACCTTTGGTGGTGTTGAGAAAGTATTCAGTATTCTAATGCTTCTGACAGCTTGTGC
TATGGCATTCGCACATGGTTCTAATGATGTCGCTAATGCGATTGGTCCACTTTCTGCGGTCGTTTCGATTGTAGAACATG
GTGGGCAAATTTTGCCCAAAACACAATTGGCTTGGTGGATCTTACCACTTGGTGCAATCGGTATTGTGATGGGCTTAGTC
GTATTGGGTTATAAAGTGATGGCAACCATTGGAACAGGCATCACGGATCTCACGCCGAGTCGTGGTTTTGCGGCGCAATT
TGCGACAGCCATCACCGTTGTTGTGGCGTCAGGTACTGGATTGCCAATTTCAACCACGCAAACATTGGTAGGCGCCGTAT
TAGGTGTCGGTTTTGCACGTGGTATTGCTGCACTCAACCTGAATGTGATCCGCAATATTATTGCTTCTTGGATCGTCACT
TTACCTGCAGGTGCATTTTTTGCCATTATCATTTATTATGTACTTAGCTTTATTTTCCACTAA

Upstream 100 bases:

>100_bases
AATGGGTTGGGGTCTTAGCGGATCAAGCTCAGCGCGTAGGATCACGAATTGAGTTAATGTTAGCTCGTTCATAACCCATC
GGTTTTAAGGAAGAACAAAA

Downstream 100 bases:

>100_bases
TATGTTATAAAGTGTGGTGCCTAAGCCACACTTTTCATTTTGTTTTACTATAGGATATTGTTTTATGCAAAAAATCGCTA
AAGTCTTACTCTCTTGTCTT

Product: hypothetical protein

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MELLNQYGTLLVFITAAFGFFMAFGIGANDVSNAMGTSVGSGTITAKQAIIIAMIFESAGAYLAGGEVTETIKSGIIDPM
KFVDTPDILVLGMMAALFASGLWLLIASRMGWPVSTTHSIVGAVVGFACVTVGKEAVEWSTIKNIVGSWFITPVIAGIVA
YGIFASTQKLIFDTDEPLKNAQKYGPYYMGITAFILCIVTLTKGLKHIGLHLNGFEVFLISLLIGIISIVVCYFYFRSPN
FIQKVQRGTFGGVEKVFSILMLLTACAMAFAHGSNDVANAIGPLSAVVSIVEHGGQILPKTQLAWWILPLGAIGIVMGLV
VLGYKVMATIGTGITDLTPSRGFAAQFATAITVVVASGTGLPISTTQTLVGAVLGVGFARGIAALNLNVIRNIIASWIVT
LPAGAFFAIIIYYVLSFIFH

Sequences:

>Translated_420_residues
MELLNQYGTLLVFITAAFGFFMAFGIGANDVSNAMGTSVGSGTITAKQAIIIAMIFESAGAYLAGGEVTETIKSGIIDPM
KFVDTPDILVLGMMAALFASGLWLLIASRMGWPVSTTHSIVGAVVGFACVTVGKEAVEWSTIKNIVGSWFITPVIAGIVA
YGIFASTQKLIFDTDEPLKNAQKYGPYYMGITAFILCIVTLTKGLKHIGLHLNGFEVFLISLLIGIISIVVCYFYFRSPN
FIQKVQRGTFGGVEKVFSILMLLTACAMAFAHGSNDVANAIGPLSAVVSIVEHGGQILPKTQLAWWILPLGAIGIVMGLV
VLGYKVMATIGTGITDLTPSRGFAAQFATAITVVVASGTGLPISTTQTLVGAVLGVGFARGIAALNLNVIRNIIASWIVT
LPAGAFFAIIIYYVLSFIFH
>Mature_420_residues
MELLNQYGTLLVFITAAFGFFMAFGIGANDVSNAMGTSVGSGTITAKQAIIIAMIFESAGAYLAGGEVTETIKSGIIDPM
KFVDTPDILVLGMMAALFASGLWLLIASRMGWPVSTTHSIVGAVVGFACVTVGKEAVEWSTIKNIVGSWFITPVIAGIVA
YGIFASTQKLIFDTDEPLKNAQKYGPYYMGITAFILCIVTLTKGLKHIGLHLNGFEVFLISLLIGIISIVVCYFYFRSPN
FIQKVQRGTFGGVEKVFSILMLLTACAMAFAHGSNDVANAIGPLSAVVSIVEHGGQILPKTQLAWWILPLGAIGIVMGLV
VLGYKVMATIGTGITDLTPSRGFAAQFATAITVVVASGTGLPISTTQTLVGAVLGVGFARGIAALNLNVIRNIIASWIVT
LPAGAFFAIIIYYVLSFIFH

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=234, Percent_Identity=37.6068376068376, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI5803173, Length=208, Percent_Identity=37.9807692307692, Blast_Score=145, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI25146401, Length=444, Percent_Identity=34.4594594594595, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71981576, Length=442, Percent_Identity=35.7466063348416, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17557328, Length=496, Percent_Identity=28.6290322580645, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI32566716, Length=236, Percent_Identity=36.4406779661017, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17539280, Length=190, Percent_Identity=41.0526315789474, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17536725, Length=163, Percent_Identity=34.3558282208589, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319773, Length=169, Percent_Identity=37.8698224852071, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356511, Length=187, Percent_Identity=44.9197860962567, Blast_Score=162, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 44348; Mature: 44348

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLNQYGTLLVFITAAFGFFMAFGIGANDVSNAMGTSVGSGTITAKQAIIIAMIFESAG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
AYLAGGEVTETIKSGIIDPMKFVDTPDILVLGMMAALFASGLWLLIASRMGWPVSTTHSI
CEEECCHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VGAVVGFACVTVGKEAVEWSTIKNIVGSWFITPVIAGIVAYGIFASTQKLIFDTDEPLKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCHHHHH
AQKYGPYYMGITAFILCIVTLTKGLKHIGLHLNGFEVFLISLLIGIISIVVCYFYFRSPN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
FIQKVQRGTFGGVEKVFSILMLLTACAMAFAHGSNDVANAIGPLSAVVSIVEHGGQILPK
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
TQLAWWILPLGAIGIVMGLVVLGYKVMATIGTGITDLTPSRGFAAQFATAITVVVASGTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEECCCC
LPISTTQTLVGAVLGVGFARGIAALNLNVIRNIIASWIVTLPAGAFFAIIIYYVLSFIFH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELLNQYGTLLVFITAAFGFFMAFGIGANDVSNAMGTSVGSGTITAKQAIIIAMIFESAG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
AYLAGGEVTETIKSGIIDPMKFVDTPDILVLGMMAALFASGLWLLIASRMGWPVSTTHSI
CEEECCHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VGAVVGFACVTVGKEAVEWSTIKNIVGSWFITPVIAGIVAYGIFASTQKLIFDTDEPLKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCHHHHH
AQKYGPYYMGITAFILCIVTLTKGLKHIGLHLNGFEVFLISLLIGIISIVVCYFYFRSPN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
FIQKVQRGTFGGVEKVFSILMLLTACAMAFAHGSNDVANAIGPLSAVVSIVEHGGQILPK
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
TQLAWWILPLGAIGIVMGLVVLGYKVMATIGTGITDLTPSRGFAAQFATAITVVVASGTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEECCCC
LPISTTQTLVGAVLGVGFARGIAALNLNVIRNIIASWIVTLPAGAFFAIIIYYVLSFIFH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]