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The map label for this gene is tadA [H]

Identifier: 15601943

GI number: 15601943

Start: 106080

End: 106580

Strand: Reverse

Name: tadA [H]

Synonym: PM0078

Alternate gene names: 15601943

Gene position: 106580-106080 (Counterclockwise)

Preceding gene: 15601944

Following gene: 15601938

Centisome position: 4.72

GC content: 45.11

Gene sequence:

>501_bases
ATGCAATCTGACATGGATGAAAAATGGATGCGTCATGCATTACGCTTGGCGGATAAAGCAGAGCAATTAGGCGAGATTCC
GGTGGGTGCCGTGTTAGTCGATGAGCAGGGAAATCTATTAGGTGAAGGGTGGAATTTATCCATTAGTGAATCCGACCCCA
CTGCACATGCTGAAATTGTCGCATTACGTCAAGGCGGGCAACGCTTACAAAACTACCGCCTGCTCAACACCACGTTGTAT
GTCACCCTGGAACCCTGCACCATGTGTGCTGGGGCAATTTTACACAGCCGTATTAAACGTCTGGTGTTTGGTGCTAGCGA
TTACAAAACCGGCGCCGTCGGTTCACGTTTTCATTTTTTTGATGACTATAAAATGAATCATGCGATAGAAATTACCGCTG
GCGTATTGCAAGAAGAATGTAGCCAAAAAATCAGCGCCTTTTTCCAAAAACGCCGAGAACAACAAAAAATCGCTAAACAA
AAAAGCCACCTTGAAACATAA

Upstream 100 bases:

>100_bases
ATTTAGAAACTTGGGTGACTATGGATGATTTTAAGGTCACGGGCTATCAATGCCACGATGCCATTAAATATCCTTTCTCT
GTGTAAGAGGTCGCGTCAAG

Downstream 100 bases:

>100_bases
GGTGGCGAGTTGTGTTGAAAAGCATCAGCATATCATGCCTTCCTTTTGGTTTATTTCGTTGTCTTGCAAAACTTTTTTAA
AATGTACCGCACTTTCCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MQSDMDEKWMRHALRLADKAEQLGEIPVGAVLVDEQGNLLGEGWNLSISESDPTAHAEIVALRQGGQRLQNYRLLNTTLY
VTLEPCTMCAGAILHSRIKRLVFGASDYKTGAVGSRFHFFDDYKMNHAIEITAGVLQEECSQKISAFFQKRREQQKIAKQ
KSHLET

Sequences:

>Translated_166_residues
MQSDMDEKWMRHALRLADKAEQLGEIPVGAVLVDEQGNLLGEGWNLSISESDPTAHAEIVALRQGGQRLQNYRLLNTTLY
VTLEPCTMCAGAILHSRIKRLVFGASDYKTGAVGSRFHFFDDYKMNHAIEITAGVLQEECSQKISAFFQKRREQQKIAKQ
KSHLET
>Mature_166_residues
MQSDMDEKWMRHALRLADKAEQLGEIPVGAVLVDEQGNLLGEGWNLSISESDPTAHAEIVALRQGGQRLQNYRLLNTTLY
VTLEPCTMCAGAILHSRIKRLVFGASDYKTGAVGSRFHFFDDYKMNHAIEITAGVLQEECSQKISAFFQKRREQQKIAKQ
KSHLET

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=168, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=58.4415584415584, Blast_Score=186, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=34.2281879194631, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=120, Percent_Identity=35, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=97, Percent_Identity=32.9896907216495, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=105, Percent_Identity=39.0476190476191, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=167, Percent_Identity=30.5389221556886, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18723; Mature: 18723

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSDMDEKWMRHALRLADKAEQLGEIPVGAVLVDEQGNLLGEGWNLSISESDPTAHAEIV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCEEEECCCCCCCHHHHH
ALRQGGQRLQNYRLLNTTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAVGSRFHFF
HHHHHHHHHHCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
DDYKMNHAIEITAGVLQEECSQKISAFFQKRREQQKIAKQKSHLET
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSDMDEKWMRHALRLADKAEQLGEIPVGAVLVDEQGNLLGEGWNLSISESDPTAHAEIV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCEEEECCCCCCCHHHHH
ALRQGGQRLQNYRLLNTTLYVTLEPCTMCAGAILHSRIKRLVFGASDYKTGAVGSRFHFF
HHHHHHHHHHCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
DDYKMNHAIEITAGVLQEECSQKISAFFQKRREQQKIAKQKSHLET
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]