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The map label for this gene is dsbB

Identifier: 15601911

GI number: 15601911

Start: 49859

End: 50395

Strand: Reverse

Name: dsbB

Synonym: PM0046

Alternate gene names: 15601911

Gene position: 50395-49859 (Counterclockwise)

Preceding gene: 15601912

Following gene: 15601909

Centisome position: 2.23

GC content: 42.83

Gene sequence:

>537_bases
ATGCTAAGCTTTTTTAAGACACTCTCAACAAAACGAAGTGCATGGTTTCTATTGTTTAGCTCAGCTTTACTATTAGAGGC
TATCGCTCTTTATTTTCAACATGGCATGGGGCTCGCCCCTTGTGTCATGTGTATTTACGAGAGGGTAGCTATTCTTGGCA
TTGCTTTCTCCGGTTTATTGGGGTTACTCTACCCGAGTTCGATGCTTTTGCGCCTTGTGGCGTTATTAATTGGTTTAAGC
AGTGCAATCAAAGGATTAATGATTAGCATCACCCATTTAGATCTACAACTTTACCCTGCACCTTGGAAACAATGTTCAGC
GGTGGCAGAATTTCCCGAGACTTTACCCTTAGATCAGTGGTTTCCTGCGCTCTTCCTCCCTTCAGGCTCATGCAGTGAAG
TAACATGGCAATTTCTCGGCTTTTCTATGGTGCAATGGATCGTCGTCATTTTTGCACTCTATACCTTATTACTTGCTCTC
ATTTTCATCAGCCAAGTCAAACGTCTAAAACCCAAGCAGCGCAGACTCTTTCATTAA

Upstream 100 bases:

>100_bases
TGGTTTATTGGCTGTGGAATATATTTTGCCTGGCGCAACCAATGTGCTCATTCAAATTGGTTTATTAAAACCAATGTAAT
GACAAGTAAAAGGAGGAAAC

Downstream 100 bases:

>100_bases
GTCATAAAAAATGGTGCGATAAAGCACCATTTTTCATTTCTCGTTCGATATAGATTAAATTTCTTGCACGACAAACTGCA
GGGAATGTCTTGCTAATAAT

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MLSFFKTLSTKRSAWFLLFSSALLLEAIALYFQHGMGLAPCVMCIYERVAILGIAFSGLLGLLYPSSMLLRLVALLIGLS
SAIKGLMISITHLDLQLYPAPWKQCSAVAEFPETLPLDQWFPALFLPSGSCSEVTWQFLGFSMVQWIVVIFALYTLLLAL
IFISQVKRLKPKQRRLFH

Sequences:

>Translated_178_residues
MLSFFKTLSTKRSAWFLLFSSALLLEAIALYFQHGMGLAPCVMCIYERVAILGIAFSGLLGLLYPSSMLLRLVALLIGLS
SAIKGLMISITHLDLQLYPAPWKQCSAVAEFPETLPLDQWFPALFLPSGSCSEVTWQFLGFSMVQWIVVIFALYTLLLAL
IFISQVKRLKPKQRRLFH
>Mature_178_residues
MLSFFKTLSTKRSAWFLLFSSALLLEAIALYFQHGMGLAPCVMCIYERVAILGIAFSGLLGLLYPSSMLLRLVALLIGLS
SAIKGLMISITHLDLQLYPAPWKQCSAVAEFPETLPLDQWFPALFLPSGSCSEVTWQFLGFSMVQWIVVIFALYTLLLAL
IFISQVKRLKPKQRRLFH

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=177, Percent_Identity=46.3276836158192, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_PASMU (Q9L6B3)

Other databases:

- EMBL:   AF237925
- EMBL:   AE004439
- RefSeq:   NP_244983.1
- ProteinModelPortal:   Q9L6B3
- SMR:   Q9L6B3
- GeneID:   1243393
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0046
- NMPDR:   fig|272843.1.peg.46
- HOGENOM:   HBG637909
- OMA:   ALYFQHV
- ProtClustDB:   PRK01749
- BioCyc:   PMUL272843:PM0046-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 20036; Mature: 20036

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbaf4740)-; HASH(0xbdc03cc)-; HASH(0xbdc3c8c)-; HASH(0xbdb8f14)-;

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFFKTLSTKRSAWFLLFSSALLLEAIALYFQHGMGLAPCVMCIYERVAILGIAFSGLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GLLYPSSMLLRLVALLIGLSSAIKGLMISITHLDLQLYPAPWKQCSAVAEFPETLPLDQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCHHHH
FPALFLPSGSCSEVTWQFLGFSMVQWIVVIFALYTLLLALIFISQVKRLKPKQRRLFH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCH
>Mature Secondary Structure
MLSFFKTLSTKRSAWFLLFSSALLLEAIALYFQHGMGLAPCVMCIYERVAILGIAFSGLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GLLYPSSMLLRLVALLIGLSSAIKGLMISITHLDLQLYPAPWKQCSAVAEFPETLPLDQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCHHHH
FPALFLPSGSCSEVTWQFLGFSMVQWIVVIFALYTLLLALIFISQVKRLKPKQRRLFH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10873488; 11248100