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The map label for this gene is 15595032

Identifier: 15595032

GI number: 15595032

Start: 728666

End: 729619

Strand: Direct

Name: 15595032

Synonym: BB0687

Alternate gene names: NA

Gene position: 728666-729619 (Clockwise)

Preceding gene: 15595031

Following gene: 15595033

Centisome position: 80.01

GC content: 32.39

Gene sequence:

>954_bases
ATGGATTTGATTAGTTTTTCTGTACCCGGAAATTTACTTTTAATGGGGGAGTATACTATTTTAGAGGAAAAGGGATTGGG
GTTGGCAATTGCCATCAACAAGAGAGCATTTTTTTCTTTTAAAAAGAGCGATTCTTGGCGCTTTTTTAGTAAAAAGAAAA
AAATAGACGATTTTTCTTTAATAGAAAATAGAAGCGATTTTGTTTTTAAAATGTTTGCTTACTTGAGTCAAAATTGTTTT
TTTAATCTAGAGAATTTTGCGTATGATGTATATATTGATACAAGTAATTTTTTCTTTAATGATGGAACTAAAAAGGGATT
TGGTTCAAGTGCTGTCGTTGCTATTGGCATAGTGTGTGGGCTTTTTTTAATTCACAATGCTACCAATGTTGTTGAGAAAG
GTGAAATTTTTAAATATTGTTTGGAAGCTTACAGGTATTCTCAAGGAGGAATAGGCAGTGGATATGATATTGCTACTAGT
ATTTTTGGGGGTGTTATTGAGTTTGAAGGCGGCTTTAATCCTAAATGCAGGCAGCTGGGTGCTGTAGAGTTTAATGATTT
TTATTTGATGCAGGGTTTGCAAGCAATTAAAACTACTACGTCTATTTGTGAATACAATAAACATAGAAATTCTATTTTAG
ATTTTATATTGAAATGCAATTTGGAGATGAAAAAGCTTGTTTTAAATGCTAGCAATTCCAAATCCGCATTAATTTCTAGT
TTAAGAAGGGCTAAAGAATTGGGATTGGCAATTGGAGAGGCAATAGGAGTTTCGGCAGCTTTGCCTTCAAGTTTTGATCA
CCTTTTAGGTCAATGTGATTTGATTAAAGCTTTGGGAGCCGGAAACGAAACTTTTTTAGTTTACAGGCCCAATATTGAAG
CTTTTAATTTGTCAAAAATTATTTCAATTGTTTTAGAGAATGAAGGCATTAAGTTTGAAAGCGATAAATGCTAA

Upstream 100 bases:

>100_bases
TTCTTTGTTTGGAGGAAAATTTAAATACTATTTTAAAAGGACTTAAGCAAAATTTTACTGGCATTGATTTTATTGTTTCA
AAGGTTGGGTGTGACTTAGA

Downstream 100 bases:

>100_bases
GAATAAGAAAGCCTGCTAAAATATTGTTCTTAGGCGAACATAGCGCTGTTTATGGGTTCCCAGTTATTGGCGCTACAGTT
CCAATTTATATGGATCTGAT

Product: phosphomevalonate kinase

Products: ADP; (R)-5-diphosphomevalonate

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MDLISFSVPGNLLLMGEYTILEEKGLGLAIAINKRAFFSFKKSDSWRFFSKKKKIDDFSLIENRSDFVFKMFAYLSQNCF
FNLENFAYDVYIDTSNFFFNDGTKKGFGSSAVVAIGIVCGLFLIHNATNVVEKGEIFKYCLEAYRYSQGGIGSGYDIATS
IFGGVIEFEGGFNPKCRQLGAVEFNDFYLMQGLQAIKTTTSICEYNKHRNSILDFILKCNLEMKKLVLNASNSKSALISS
LRRAKELGLAIGEAIGVSAALPSSFDHLLGQCDLIKALGAGNETFLVYRPNIEAFNLSKIISIVLENEGIKFESDKC

Sequences:

>Translated_317_residues
MDLISFSVPGNLLLMGEYTILEEKGLGLAIAINKRAFFSFKKSDSWRFFSKKKKIDDFSLIENRSDFVFKMFAYLSQNCF
FNLENFAYDVYIDTSNFFFNDGTKKGFGSSAVVAIGIVCGLFLIHNATNVVEKGEIFKYCLEAYRYSQGGIGSGYDIATS
IFGGVIEFEGGFNPKCRQLGAVEFNDFYLMQGLQAIKTTTSICEYNKHRNSILDFILKCNLEMKKLVLNASNSKSALISS
LRRAKELGLAIGEAIGVSAALPSSFDHLLGQCDLIKALGAGNETFLVYRPNIEAFNLSKIISIVLENEGIKFESDKC
>Mature_317_residues
MDLISFSVPGNLLLMGEYTILEEKGLGLAIAINKRAFFSFKKSDSWRFFSKKKKIDDFSLIENRSDFVFKMFAYLSQNCF
FNLENFAYDVYIDTSNFFFNDGTKKGFGSSAVVAIGIVCGLFLIHNATNVVEKGEIFKYCLEAYRYSQGGIGSGYDIATS
IFGGVIEFEGGFNPKCRQLGAVEFNDFYLMQGLQAIKTTTSICEYNKHRNSILDFILKCNLEMKKLVLNASNSKSALISS
LRRAKELGLAIGEAIGVSAALPSSFDHLLGQCDLIKALGAGNETFLVYRPNIEAFNLSKIISIVLENEGIKFESDKC

Specific function: Unknown

COG id: COG3890

COG function: function code I; Phosphomevalonate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.4.2

Molecular weight: Translated: 35260; Mature: 35260

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLISFSVPGNLLLMGEYTILEEKGLGLAIAINKRAFFSFKKSDSWRFFSKKKKIDDFSL
CCEEEEECCCCEEEEECEEEEECCCCEEEEEECCCEEEEECCCCCEEEHHHHCCCCCHHH
IENRSDFVFKMFAYLSQNCFFNLENFAYDVYIDTSNFFFNDGTKKGFGSSAVVAIGIVCG
HCCCCHHHHHHHHHHHHCCEEEECCEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHH
LFLIHNATNVVEKGEIFKYCLEAYRYSQGGIGSGYDIATSIFGGVIEFEGGFNPKCRQLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEEECCCCCHHHHHCC
AVEFNDFYLMQGLQAIKTTTSICEYNKHRNSILDFILKCNLEMKKLVLNASNSKSALISS
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHHHH
LRRAKELGLAIGEAIGVSAALPSSFDHLLGQCDLIKALGAGNETFLVYRPNIEAFNLSKI
HHHHHHHHHHHHHHHCCHHCCCCHHHHHHCHHHHHHHHCCCCCEEEEECCCCCEECHHHH
ISIVLENEGIKFESDKC
HHHHCCCCCCEECCCCC
>Mature Secondary Structure
MDLISFSVPGNLLLMGEYTILEEKGLGLAIAINKRAFFSFKKSDSWRFFSKKKKIDDFSL
CCEEEEECCCCEEEEECEEEEECCCCEEEEEECCCEEEEECCCCCEEEHHHHCCCCCHHH
IENRSDFVFKMFAYLSQNCFFNLENFAYDVYIDTSNFFFNDGTKKGFGSSAVVAIGIVCG
HCCCCHHHHHHHHHHHHCCEEEECCEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHH
LFLIHNATNVVEKGEIFKYCLEAYRYSQGGIGSGYDIATSIFGGVIEFEGGFNPKCRQLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEEECCCCCHHHHHCC
AVEFNDFYLMQGLQAIKTTTSICEYNKHRNSILDFILKCNLEMKKLVLNASNSKSALISS
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHHHH
LRRAKELGLAIGEAIGVSAALPSSFDHLLGQCDLIKALGAGNETFLVYRPNIEAFNLSKI
HHHHHHHHHHHHHHHCCHHCCCCHHHHHHCHHHHHHHHCCCCCEEEEECCCCCEECHHHH
ISIVLENEGIKFESDKC
HHHHCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; (R)-5-phosphomevalonate

Specific reaction: ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA