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The map label for this gene is prpE [H]

Identifier: 154247704

GI number: 154247704

Start: 4187431

End: 4188186

Strand: Direct

Name: prpE [H]

Synonym: Xaut_3780

Alternate gene names: 154247704

Gene position: 4187431-4188186 (Clockwise)

Preceding gene: 154247702

Following gene: 154247705

Centisome position: 78.88

GC content: 63.62

Gene sequence:

>756_bases
ATGGCAATGCTGAAGCTCCGCCCCAATCCTTTGGCTGAAGCCGCGTTCGCCCCGCCGGTGCCGCGCCTTCCGCCGAACAA
GCGGGTCTATGCCGTCGGGGACATCCACGGTCACCTCGATCTGCTCAAGCGGCTGCAGGCGGCGATCGACGAGGACATGC
TCGTGCATCCGGGCGTCGATTGCATCGAGGTCTATCTCGGCGACTATGTGGACCGCGGCCCGCAGTCGGCGGCGGTCATA
GATGCGTTGATCGAACGTCAGGCCAGCCGCAAGGCGGTGTGCATCAGCGGCAACCACGAGGCGGTGATGATCGACGCCCT
CCTGTCGCGGGAGACGTTTGCCCGCTGGCTGAAGATGGGCGGCCTGGAGACGGTCTTCTCTTATGTGGGTCACCGGCGCA
ACCTGGACGAGAATACGCTCTGGAGCCTGTGGCGCGCAGCCGTGTCATCGGCGCATCTGGCGTTTCTGAAGCGACTGTCC
AGCCATTTCGTCTGCGGCGACTATCTGTTCGTCCACGCGGGATTGCGCCCCGGCATCCCGCTGGAGGAGCAGAGCCGCGA
GGACATGATGTGGATCCGGCGCGAATTCCTCGATTGTCCCGACTGGCTGGGCCATTGCGTCGTGCACGGCCACACTCCGA
CCAAGGTGCCGGAGGTATTGCCCAACCGAATTAACATCGATACCGGGGCCTATGCCTCAGGGCATCTGACCTGTCTGGTG
CTCGAAGGCGCCGACTGCTTCCATATCACGACCTGA

Upstream 100 bases:

>100_bases
TGCAACAAAGGCTCTTCGCAGTGCGGGCGGGCGTGTGATAGACTTTTAGCCTGATCGTGCCCCACGGGGGTGCCGCAGTG
GCAAAGGTCAAGCCCCGACC

Downstream 100 bases:

>100_bases
TTCCCTGACTGTCTCCAGCGGCGCTGTGCGGAGCGATAGCCAGATACCTCAATTTTGGAGGTATTATTTTAACTTTTTCG
CATGGAACCCCGCATCGGCA

Product: metallophosphoesterase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAMLKLRPNPLAEAAFAPPVPRLPPNKRVYAVGDIHGHLDLLKRLQAAIDEDMLVHPGVDCIEVYLGDYVDRGPQSAAVI
DALIERQASRKAVCISGNHEAVMIDALLSRETFARWLKMGGLETVFSYVGHRRNLDENTLWSLWRAAVSSAHLAFLKRLS
SHFVCGDYLFVHAGLRPGIPLEEQSREDMMWIRREFLDCPDWLGHCVVHGHTPTKVPEVLPNRINIDTGAYASGHLTCLV
LEGADCFHITT

Sequences:

>Translated_251_residues
MAMLKLRPNPLAEAAFAPPVPRLPPNKRVYAVGDIHGHLDLLKRLQAAIDEDMLVHPGVDCIEVYLGDYVDRGPQSAAVI
DALIERQASRKAVCISGNHEAVMIDALLSRETFARWLKMGGLETVFSYVGHRRNLDENTLWSLWRAAVSSAHLAFLKRLS
SHFVCGDYLFVHAGLRPGIPLEEQSREDMMWIRREFLDCPDWLGHCVVHGHTPTKVPEVLPNRINIDTGAYASGHLTCLV
LEGADCFHITT
>Mature_250_residues
AMLKLRPNPLAEAAFAPPVPRLPPNKRVYAVGDIHGHLDLLKRLQAAIDEDMLVHPGVDCIEVYLGDYVDRGPQSAAVID
ALIERQASRKAVCISGNHEAVMIDALLSRETFARWLKMGGLETVFSYVGHRRNLDENTLWSLWRAAVSSAHLAFLKRLSS
HFVCGDYLFVHAGLRPGIPLEEQSREDMMWIRREFLDCPDWLGHCVVHGHTPTKVPEVLPNRINIDTGAYASGHLTCLVL
EGADCFHITT

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.17 [H]

Molecular weight: Translated: 28021; Mature: 27889

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMLKLRPNPLAEAAFAPPVPRLPPNKRVYAVGDIHGHLDLLKRLQAAIDEDMLVHPGVD
CCEEEECCCCHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEECCCHH
CIEVYLGDYVDRGPQSAAVIDALIERQASRKAVCISGNHEAVMIDALLSRETFARWLKMG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHC
GLETVFSYVGHRRNLDENTLWSLWRAAVSSAHLAFLKRLSSHFVCGDYLFVHAGLRPGIP
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHEEECCCCCCCC
LEEQSREDMMWIRREFLDCPDWLGHCVVHGHTPTKVPEVLPNRINIDTGAYASGHLTCLV
CCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCCCHHHHHCCCCCCCCCCCCCCCCEEEEE
LEGADCFHITT
EECCCEEEECC
>Mature Secondary Structure 
AMLKLRPNPLAEAAFAPPVPRLPPNKRVYAVGDIHGHLDLLKRLQAAIDEDMLVHPGVD
CEEEECCCCHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEECCCHH
CIEVYLGDYVDRGPQSAAVIDALIERQASRKAVCISGNHEAVMIDALLSRETFARWLKMG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHC
GLETVFSYVGHRRNLDENTLWSLWRAAVSSAHLAFLKRLSSHFVCGDYLFVHAGLRPGIP
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHEEECCCCCCCC
LEEQSREDMMWIRREFLDCPDWLGHCVVHGHTPTKVPEVLPNRINIDTGAYASGHLTCLV
CCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCCCHHHHHCCCCCCCCCCCCCCCCEEEEE
LEGADCFHITT
EECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA