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The map label for this gene is dnaB [H]

Identifier: 154246345

GI number: 154246345

Start: 2682962

End: 2684443

Strand: Reverse

Name: dnaB [H]

Synonym: Xaut_2404

Alternate gene names: 154246345

Gene position: 2684443-2682962 (Counterclockwise)

Preceding gene: 154246347

Following gene: 154246344

Centisome position: 50.56

GC content: 66.46

Gene sequence:

>1482_bases
ATGCTCGACCTCCCCAATCCGGGTGATCTCGAACCCTCCTATCGTCAGGCCCCGCACAATCTGGAGGCGGAGCAGGCGCT
GCTGGGCGCCATCCTCGTCAACAACGAGGCGTTCTACCGGGTCTCCGACTTCCTCGAGCCGCGCCATTTCTACGAGCCCA
TCCACGCCCGGGTGTTCGAACTGGCGAGCGCGCTGATCCGCGCCGGCAAGCTCGCCACGCCGGTGACGCTCAAGACCTTC
CTGCCCTCGGACCTCGACGTGGCCGGCCTCACCGGGCCGCAATATCTCGCCCGCCTCGCGGCGGAGGCGACCACCATCAT
CAATTCCGAGGACTACGGGCGCACCATCTACGACCTGTCGGTGCGGCGCGACCTGATCCGCATCGGCGAGGAGATCGTGA
ACGAGGCGTTCGACGCCCCGGTGGACGCCACCCCGCAGGACCAGATCGAGCAGGCGGAGAAGCGGCTTTACGAGATCGCC
GAGACCGGCCGCTACGACGGCGGCTTCCAGCGCTTCGGCGAGGCGCTGCGCGAGGCGGTGGACATGGCCTCCAAGGCCTT
CCAGCGCGACGGCCACCTCTCCGGCATCGCCACGGCGCTGGACGACCTCGACCACCAGATGGGCGGCTTGCAGCCCTCCG
ACCTCGTGATCCTCGCCGGCCGCCCGGCCATGGGCAAGACCGCGCTCGCCACCAACATCGCCTTCAACATCGCCGCCGCC
TATCGCGGCGAGACGCGGCCCGACGGCGGCATCGAGACCGTGTCGGGGGGCATCGTTGGCTTCTTCTCGCTGGAAATGTC
GGCCGAGCAGCTGGCCACCCGTATCCTCGCCGAGCAGGCCGAGATCGCCTCCTACAAGATCCGCCGCGGCGACATCTCGG
AGAGCGAATTCTCCAAGCTCGCCGCCGCCGCCCAGACCATGCAGACCATCCCGCTTTATATCGACGACACCGGCGGCCTC
TCCATCGCCCAGTTGGTGGCCCGGGCGCGGCGGCTGAAGCGCCAGCGCGGGCTCGACTTCATGGTGGTGGACTATCTCCA
GCTCCTGTCCGGCTCGTCCAAAAGCTCGTCCCAGAACCGCGTCCAGGAGATCACCGAGATCACCACCGGACTGAAGGCCT
TGGCGAAAGAGCTGCAAGTGCCCATCATGGCGCTGTCGCAGCTGTCGCGTCAGGTTGAAGCGCGAGACGACAAGAGGCCG
CAATTGTCGGACCTGCGCGAATCCGGCTCCATCGAGCAGGACGCCGACGTGGTCATGTTTGTGTTCCGGGAGGAATATTA
CCTTAAAAGCAAGGAGCCGAAGGCCGGCACAGAGGAGTGGTTCAAGTGGGAGATCGAGATGAAGGCGGCCGAGAACACGG
CCGAGGTCATCATCGGAAAGCAGCGCCACGGCCCCACGGGGACGGTGAAGGTGCATTTCGAGCCCCAGTTCACCCGCTTC
TCCAACCTGGCGCGGGAGGACCACCTGCCGGAGCGCCACTGA

Upstream 100 bases:

>100_bases
AAAAAAGCACCCCCTTGATTTCGGAACAAACAAAGAACTTACTGTGCTCGGGACCCCGGACTTGGTAAGGAAGTGACCCA
TCCAGCGGAACCTTGGCGCC

Downstream 100 bases:

>100_bases
GCGCGCCCTCGCCGGAGGAGGCCGAAGCTGAGGCCGCGGCCCTCGCCGCGGCGCACGAGACCGCCGACCGCGAGGCGCGG
GAAGCCGGCGCAATCCTCAC

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MLDLPNPGDLEPSYRQAPHNLEAEQALLGAILVNNEAFYRVSDFLEPRHFYEPIHARVFELASALIRAGKLATPVTLKTF
LPSDLDVAGLTGPQYLARLAAEATTIINSEDYGRTIYDLSVRRDLIRIGEEIVNEAFDAPVDATPQDQIEQAEKRLYEIA
ETGRYDGGFQRFGEALREAVDMASKAFQRDGHLSGIATALDDLDHQMGGLQPSDLVILAGRPAMGKTALATNIAFNIAAA
YRGETRPDGGIETVSGGIVGFFSLEMSAEQLATRILAEQAEIASYKIRRGDISESEFSKLAAAAQTMQTIPLYIDDTGGL
SIAQLVARARRLKRQRGLDFMVVDYLQLLSGSSKSSSQNRVQEITEITTGLKALAKELQVPIMALSQLSRQVEARDDKRP
QLSDLRESGSIEQDADVVMFVFREEYYLKSKEPKAGTEEWFKWEIEMKAAENTAEVIIGKQRHGPTGTVKVHFEPQFTRF
SNLAREDHLPERH

Sequences:

>Translated_493_residues
MLDLPNPGDLEPSYRQAPHNLEAEQALLGAILVNNEAFYRVSDFLEPRHFYEPIHARVFELASALIRAGKLATPVTLKTF
LPSDLDVAGLTGPQYLARLAAEATTIINSEDYGRTIYDLSVRRDLIRIGEEIVNEAFDAPVDATPQDQIEQAEKRLYEIA
ETGRYDGGFQRFGEALREAVDMASKAFQRDGHLSGIATALDDLDHQMGGLQPSDLVILAGRPAMGKTALATNIAFNIAAA
YRGETRPDGGIETVSGGIVGFFSLEMSAEQLATRILAEQAEIASYKIRRGDISESEFSKLAAAAQTMQTIPLYIDDTGGL
SIAQLVARARRLKRQRGLDFMVVDYLQLLSGSSKSSSQNRVQEITEITTGLKALAKELQVPIMALSQLSRQVEARDDKRP
QLSDLRESGSIEQDADVVMFVFREEYYLKSKEPKAGTEEWFKWEIEMKAAENTAEVIIGKQRHGPTGTVKVHFEPQFTRF
SNLAREDHLPERH
>Mature_493_residues
MLDLPNPGDLEPSYRQAPHNLEAEQALLGAILVNNEAFYRVSDFLEPRHFYEPIHARVFELASALIRAGKLATPVTLKTF
LPSDLDVAGLTGPQYLARLAAEATTIINSEDYGRTIYDLSVRRDLIRIGEEIVNEAFDAPVDATPQDQIEQAEKRLYEIA
ETGRYDGGFQRFGEALREAVDMASKAFQRDGHLSGIATALDDLDHQMGGLQPSDLVILAGRPAMGKTALATNIAFNIAAA
YRGETRPDGGIETVSGGIVGFFSLEMSAEQLATRILAEQAEIASYKIRRGDISESEFSKLAAAAQTMQTIPLYIDDTGGL
SIAQLVARARRLKRQRGLDFMVVDYLQLLSGSSKSSSQNRVQEITEITTGLKALAKELQVPIMALSQLSRQVEARDDKRP
QLSDLRESGSIEQDADVVMFVFREEYYLKSKEPKAGTEEWFKWEIEMKAAENTAEVIIGKQRHGPTGTVKVHFEPQFTRF
SNLAREDHLPERH

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins [

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=472, Percent_Identity=37.2881355932203, Blast_Score=287, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 54689; Mature: 54689

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLPNPGDLEPSYRQAPHNLEAEQALLGAILVNNEAFYRVSDFLEPRHFYEPIHARVFE
CCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHH
LASALIRAGKLATPVTLKTFLPSDLDVAGLTGPQYLARLAAEATTIINSEDYGRTIYDLS
HHHHHHHCCCCCCCEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEHHH
VRRDLIRIGEEIVNEAFDAPVDATPQDQIEQAEKRLYEIAETGRYDGGFQRFGEALREAV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DMASKAFQRDGHLSGIATALDDLDHQMGGLQPSDLVILAGRPAMGKTALATNIAFNIAAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
YRGETRPDGGIETVSGGIVGFFSLEMSAEQLATRILAEQAEIASYKIRRGDISESEFSKL
HCCCCCCCCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
AAAAQTMQTIPLYIDDTGGLSIAQLVARARRLKRQRGLDFMVVDYLQLLSGSSKSSSQNR
HHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHH
VQEITEITTGLKALAKELQVPIMALSQLSRQVEARDDKRPQLSDLRESGSIEQDADVVMF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEEEE
VFREEYYLKSKEPKAGTEEWFKWEIEMKAAENTAEVIIGKQRHGPTGTVKVHFEPQFTRF
EEHHHHHHCCCCCCCCCHHHEEEEEEEECCCCCHHHEEECCCCCCCCEEEEEECCCHHHH
SNLAREDHLPERH
HHHHHHCCCCCCC
>Mature Secondary Structure
MLDLPNPGDLEPSYRQAPHNLEAEQALLGAILVNNEAFYRVSDFLEPRHFYEPIHARVFE
CCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHH
LASALIRAGKLATPVTLKTFLPSDLDVAGLTGPQYLARLAAEATTIINSEDYGRTIYDLS
HHHHHHHCCCCCCCEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEHHH
VRRDLIRIGEEIVNEAFDAPVDATPQDQIEQAEKRLYEIAETGRYDGGFQRFGEALREAV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
DMASKAFQRDGHLSGIATALDDLDHQMGGLQPSDLVILAGRPAMGKTALATNIAFNIAAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
YRGETRPDGGIETVSGGIVGFFSLEMSAEQLATRILAEQAEIASYKIRRGDISESEFSKL
HCCCCCCCCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
AAAAQTMQTIPLYIDDTGGLSIAQLVARARRLKRQRGLDFMVVDYLQLLSGSSKSSSQNR
HHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHH
VQEITEITTGLKALAKELQVPIMALSQLSRQVEARDDKRPQLSDLRESGSIEQDADVVMF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEEEE
VFREEYYLKSKEPKAGTEEWFKWEIEMKAAENTAEVIIGKQRHGPTGTVKVHFEPQFTRF
EEHHHHHHCCCCCCCCCHHHEEEEEEEECCCCCHHHEEECCCCCCCCEEEEEECCCHHHH
SNLAREDHLPERH
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA