Click here to switch to the map view.

The map label for this gene is alr [H]

Identifier: 154246344

GI number: 154246344

Start: 2681787

End: 2682860

Strand: Reverse

Name: alr [H]

Synonym: Xaut_2403

Alternate gene names: 154246344

Gene position: 2682860-2681787 (Counterclockwise)

Preceding gene: 154246345

Following gene: 154246343

Centisome position: 50.53

GC content: 70.39

Gene sequence:

>1074_bases
GTGGATCTGGGCGCCATCGCCGACAACTGGCGCACCATCGCGGCGCTTGCCGCCCCGGCCGAATGCGCCGCCGTGGTCAA
GGCCAACGCCTACGGCCTCGGCATCGACCGGGTCGCTCCGGTGCTGTGGCGGGCCGGCGCGCGCAATTTCTTCGTCGCCC
ATTTCAAGGAAGCGGTGGCCCTGCGCGCCCTGCTGCCCGAGGCCATCATCTATGTGCTGAACGGCCTTCTGCCGGATTGC
GCCGCCGACTATGCGGCCGCGAATCTGCGCCCGGTGCTGGGATCGACCCCGGAAATCTCCGACTGGAGCGACTATTGCCG
CGACGCCGGCGTCAAGCTGCCCGCCGCCATCCATGTGGATACGGGCATGCACCGGCTCGGCCTGTCGCTGGAGGAGGCGG
TGCAGCTCTCCGGCACCTTCCGCCTGCTGGGCTTCACCCCCAGCCTGATCATGAGCCATCTCGCCTGCGCCGACACGCCG
GGGCACGTGCTCACCGCCCGCCAGCGCATGGTGTTCGCCGACGTGGTACGCCGCTTCCCCGGCATTCCGGGATCGCTGGC
CAATTCGGCCGGCACCCTGCTCGGCCGCGACTTCCGGTTCGAGCTGGTGCGGCCTGGCATCTTCCTCTATGGCGGCATCG
CCATCAACGGGGTACCGCCGTTGCGGCCGGTGGTGCGGCTGGAGGTGAAGGTGGTGCAGGTCTCCACCGCCCCGGCCGGC
GAGACGGTGGGCTATGGCGCCGCCCAGCGGCTGAAGCGGCCGAGCCGGCTCGCCACCGTCTCCATCGGCTATGCGGACGG
ACTGTTCCGCGCCGGCGGCTCCACCGACGCCATCAAGGGGGTGGAGGCCATCGTCCACGGCCAGCGCTGCCATCTGGTGG
GCCGCGTCTCCATGGACCTCGCCACGCTGGACATCACCGACCTGCCGGACGGCGTGGTGCAACGGGGCGACACCGCCGTC
TTCCTCGGCGACGGCATCAGCGTGGATGATCTTGCCGCCCGCTCGGGCACCATCGGCTACGAGGTGCTCACCTCACTGGG
CGCCCGCTACGCCCGCCATTACGTGGGCGGGTAA

Upstream 100 bases:

>100_bases
CGCGCCCTCGCCGGAGGAGGCCGAAGCTGAGGCCGCGGCCCTCGCCGCGGCGCACGAGACCGCCGACCGCGAGGCGCGGG
AAGCCGGCGCAATCCTCACC

Downstream 100 bases:

>100_bases
GGGGCCATCTGGACCATATGTTCCTATTTTGTGCTCTAATGGACGAGCGCAGGGAGATTCGCTCCGCAATCTGATCGGTG
CGTGCTCTAGCGGAACAGGA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MDLGAIADNWRTIAALAAPAECAAVVKANAYGLGIDRVAPVLWRAGARNFFVAHFKEAVALRALLPEAIIYVLNGLLPDC
AADYAAANLRPVLGSTPEISDWSDYCRDAGVKLPAAIHVDTGMHRLGLSLEEAVQLSGTFRLLGFTPSLIMSHLACADTP
GHVLTARQRMVFADVVRRFPGIPGSLANSAGTLLGRDFRFELVRPGIFLYGGIAINGVPPLRPVVRLEVKVVQVSTAPAG
ETVGYGAAQRLKRPSRLATVSIGYADGLFRAGGSTDAIKGVEAIVHGQRCHLVGRVSMDLATLDITDLPDGVVQRGDTAV
FLGDGISVDDLAARSGTIGYEVLTSLGARYARHYVGG

Sequences:

>Translated_357_residues
MDLGAIADNWRTIAALAAPAECAAVVKANAYGLGIDRVAPVLWRAGARNFFVAHFKEAVALRALLPEAIIYVLNGLLPDC
AADYAAANLRPVLGSTPEISDWSDYCRDAGVKLPAAIHVDTGMHRLGLSLEEAVQLSGTFRLLGFTPSLIMSHLACADTP
GHVLTARQRMVFADVVRRFPGIPGSLANSAGTLLGRDFRFELVRPGIFLYGGIAINGVPPLRPVVRLEVKVVQVSTAPAG
ETVGYGAAQRLKRPSRLATVSIGYADGLFRAGGSTDAIKGVEAIVHGQRCHLVGRVSMDLATLDITDLPDGVVQRGDTAV
FLGDGISVDDLAARSGTIGYEVLTSLGARYARHYVGG
>Mature_357_residues
MDLGAIADNWRTIAALAAPAECAAVVKANAYGLGIDRVAPVLWRAGARNFFVAHFKEAVALRALLPEAIIYVLNGLLPDC
AADYAAANLRPVLGSTPEISDWSDYCRDAGVKLPAAIHVDTGMHRLGLSLEEAVQLSGTFRLLGFTPSLIMSHLACADTP
GHVLTARQRMVFADVVRRFPGIPGSLANSAGTLLGRDFRFELVRPGIFLYGGIAINGVPPLRPVVRLEVKVVQVSTAPAG
ETVGYGAAQRLKRPSRLATVSIGYADGLFRAGGSTDAIKGVEAIVHGQRCHLVGRVSMDLATLDITDLPDGVVQRGDTAV
FLGDGISVDDLAARSGTIGYEVLTSLGARYARHYVGG

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=34.1530054644809, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790487, Length=369, Percent_Identity=32.7913279132791, Blast_Score=140, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 37665; Mature: 37665

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGAIADNWRTIAALAAPAECAAVVKANAYGLGIDRVAPVLWRAGARNFFVAHFKEAVA
CCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
LRALLPEAIIYVLNGLLPDCAADYAAANLRPVLGSTPEISDWSDYCRDAGVKLPAAIHVD
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEC
TGMHRLGLSLEEAVQLSGTFRLLGFTPSLIMSHLACADTPGHVLTARQRMVFADVVRRFP
CCHHHHCCCHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
GIPGSLANSAGTLLGRDFRFELVRPGIFLYGGIAINGVPPLRPVVRLEVKVVQVSTAPAG
CCCCHHHCCCCHHHCCCEEEEEECCCEEEEECEEECCCCCCCCEEEEEEEEEEEECCCCC
ETVGYGAAQRLKRPSRLATVSIGYADGLFRAGGSTDAIKGVEAIVHGQRCHLVGRVSMDL
CCCCCCHHHHHCCCCCEEEEEEECCCCCEECCCCCHHHHHHHHHHCCCCEEEEEEEEEEE
ATLDITDLPDGVVQRGDTAVFLGDGISVDDLAARSGTIGYEVLTSLGARYARHYVGG
EEEEECCCCHHHHHCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLGAIADNWRTIAALAAPAECAAVVKANAYGLGIDRVAPVLWRAGARNFFVAHFKEAVA
CCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
LRALLPEAIIYVLNGLLPDCAADYAAANLRPVLGSTPEISDWSDYCRDAGVKLPAAIHVD
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEC
TGMHRLGLSLEEAVQLSGTFRLLGFTPSLIMSHLACADTPGHVLTARQRMVFADVVRRFP
CCHHHHCCCHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
GIPGSLANSAGTLLGRDFRFELVRPGIFLYGGIAINGVPPLRPVVRLEVKVVQVSTAPAG
CCCCHHHCCCCHHHCCCEEEEEECCCEEEEECEEECCCCCCCCEEEEEEEEEEEECCCCC
ETVGYGAAQRLKRPSRLATVSIGYADGLFRAGGSTDAIKGVEAIVHGQRCHLVGRVSMDL
CCCCCCHHHHHCCCCCEEEEEEECCCCCEECCCCCHHHHHHHHHHCCCCEEEEEEEEEEE
ATLDITDLPDGVVQRGDTAVFLGDGISVDDLAARSGTIGYEVLTSLGARYARHYVGG
EEEEECCCCHHHHHCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA