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The map label for this gene is lysK

Identifier: 154246326

GI number: 154246326

Start: 2662458

End: 2664155

Strand: Direct

Name: lysK

Synonym: Xaut_2384

Alternate gene names: 154246326

Gene position: 2662458-2664155 (Clockwise)

Preceding gene: 154246325

Following gene: 154246327

Centisome position: 50.15

GC content: 66.08

Gene sequence:

>1698_bases
ATGTCCGCCGCCCCGTCCGATACTGCCTCGTCCGCCTTCGCCGATCCGGCCGACCTCGCCGGCGAGCTGAAGCGCGTGGC
CGAGACGGCCACGGCCTGGCCGTTCGAGGAAGCGCGCAAGCTGGTGGAGCGGCTGAAGCGCCACCCCAAGGAGCGCGGAT
CGGAAGAAGTGCTGTTCGAGACCGGCTACGGCCCCTCGGGCCTGCCGCACATCGGCACCTTCGGTGAAGTGGCGCGCACC
ACCATGGTGCGCCACGCCTTCCGCGTGCTGACTGAAGACAAGGTGAAGACCCGGCTCGTCGCCTTCTCCGACGACATGGA
CGGCCTGCGCAAGGTGCCGGACAACGTCCCCAACAAGGACATGCTGCAGAAGGCCCTGGGCCTGCCGCTGACCAAGGTGC
CCGACCCCTTCGGCACCCACGACAGTTTCGGTGAGCACAACAATGCCCGCCTGCGCGCGTTCCTGGACGCCTTCGGCTTT
CGGTATGAATTCATGTCGGCGACCGACTGCTACATGTCCGGCCGGTTCGATGCCACGCTGCTGAAGGTGCTGCATCACTA
CGAGAAGGTGATGAACGTGATGCTGCCCTCCCTGCGCGAGGAGCGGGCGGCGTCCTATTCCCCCTTCCTGCCCATCTGCC
CCCGCACGGGCCGCGTGCTCCAGGTGCCGATCCTGGAACACCATGTGAAGCACGGCACCGTCACCTACGAGGACCCGGAT
ACGAAGGAAAAGGTGACGGTCCCGGTCACCGGCGGCGGCTGCAAGCTGCAGTGGAAGCCCGACTGGGCCATGCGCTGGGT
GGCGCTGGGCGTCGATTACGAGATGGCGGGCAAAGACCTCATCGATTCCGTGAAGCTCTCCAGCCAGATCGCCAAGGCGC
TCGGCGGCGAGCCGCCGGAGGGCTTCAACTACGAGCTGTTCCTCGACGAGAAGGGGCAGAAGATCTCCAAGTCCAAGGGC
AACGGCCTGTCCATCGAGGACTGGCTGAAATACGCCTCGCCGGAGAGCCTCAGCCTGTTCATGTTCCAGTCGCCCCGCTC
GGGCAAGCGGCTCTTCTTCGATGTCATCCCGCGCAACGTGGACGATTATTTCGGCTTCCTCGGCAAGTATGAGGAGCAGG
ACTGGAAGCTGCGCCTCGGCAACCCGGTGTGGCACATCCATGCAGGCGAACCGCCCAAGGTGGACATGCCGGTGTCCTTC
ACCATGCTGCTGAATCTGGCCTCCGCCTCCAACACCGAGGATGAAAGCGTGTTGTGGGGCTTCCTCAACCGCCACGTGCC
GGGGGTGTCCGCGGAAACCCATCCCAAGCTTGCCGAACTGGTCGGCTACGCGGTCAAGTACTTCCACGATTTCGTCAAGC
CGAACAAGGTGTTCCGGGCGCCCGACGCGGTCGAGCAGGAGGCCCTCGCCAAGCTCGATGCGGCGCTGGCGGCACTGCCG
GCCGGCGCCACGGCCGACGACATCCAGAACGCGCTCTACGACGTGGCCCGCCCCATCGAGCGCTATCAGGACCTGAAGGC
GAAGGGCGCCACCCCGGAGCGGCCGGGCGTGTCCATCGAGTGGTTCAACACCCTCTACCAGGTGCTGCTCGGCCTCGGGC
GCGGCCCGCGCTTCGGCTCCTTCGTGGAGATCTACGGCGTGGCCGAGACGCGGGAGCTGATCCGCAAGGCCCTGGCCGGG
GAACTGGCGACGGCTTGA

Upstream 100 bases:

>100_bases
GAGGAGCCATCGGGTCCCGTCGCGGACGGTGTTTCGGCCCGCCCGCGTTGACGCCACCCGCCGACATTCCTAAGTTCGCG
CTCCTTTTTTGGAGCCTGCC

Downstream 100 bases:

>100_bases
GGGGTCACCATGGCCGGGCAGGTTTTGACCGAGTCGGACATTTTCTGGCCGTGGCGATTTAAAGCCTGCTGGCGCAACTC
GGCTATCTGCTGGTAGGCAT

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MSAAPSDTASSAFADPADLAGELKRVAETATAWPFEEARKLVERLKRHPKERGSEEVLFETGYGPSGLPHIGTFGEVART
TMVRHAFRVLTEDKVKTRLVAFSDDMDGLRKVPDNVPNKDMLQKALGLPLTKVPDPFGTHDSFGEHNNARLRAFLDAFGF
RYEFMSATDCYMSGRFDATLLKVLHHYEKVMNVMLPSLREERAASYSPFLPICPRTGRVLQVPILEHHVKHGTVTYEDPD
TKEKVTVPVTGGGCKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSSQIAKALGGEPPEGFNYELFLDEKGQKISKSKG
NGLSIEDWLKYASPESLSLFMFQSPRSGKRLFFDVIPRNVDDYFGFLGKYEEQDWKLRLGNPVWHIHAGEPPKVDMPVSF
TMLLNLASASNTEDESVLWGFLNRHVPGVSAETHPKLAELVGYAVKYFHDFVKPNKVFRAPDAVEQEALAKLDAALAALP
AGATADDIQNALYDVARPIERYQDLKAKGATPERPGVSIEWFNTLYQVLLGLGRGPRFGSFVEIYGVAETRELIRKALAG
ELATA

Sequences:

>Translated_565_residues
MSAAPSDTASSAFADPADLAGELKRVAETATAWPFEEARKLVERLKRHPKERGSEEVLFETGYGPSGLPHIGTFGEVART
TMVRHAFRVLTEDKVKTRLVAFSDDMDGLRKVPDNVPNKDMLQKALGLPLTKVPDPFGTHDSFGEHNNARLRAFLDAFGF
RYEFMSATDCYMSGRFDATLLKVLHHYEKVMNVMLPSLREERAASYSPFLPICPRTGRVLQVPILEHHVKHGTVTYEDPD
TKEKVTVPVTGGGCKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSSQIAKALGGEPPEGFNYELFLDEKGQKISKSKG
NGLSIEDWLKYASPESLSLFMFQSPRSGKRLFFDVIPRNVDDYFGFLGKYEEQDWKLRLGNPVWHIHAGEPPKVDMPVSF
TMLLNLASASNTEDESVLWGFLNRHVPGVSAETHPKLAELVGYAVKYFHDFVKPNKVFRAPDAVEQEALAKLDAALAALP
AGATADDIQNALYDVARPIERYQDLKAKGATPERPGVSIEWFNTLYQVLLGLGRGPRFGSFVEIYGVAETRELIRKALAG
ELATA
>Mature_564_residues
SAAPSDTASSAFADPADLAGELKRVAETATAWPFEEARKLVERLKRHPKERGSEEVLFETGYGPSGLPHIGTFGEVARTT
MVRHAFRVLTEDKVKTRLVAFSDDMDGLRKVPDNVPNKDMLQKALGLPLTKVPDPFGTHDSFGEHNNARLRAFLDAFGFR
YEFMSATDCYMSGRFDATLLKVLHHYEKVMNVMLPSLREERAASYSPFLPICPRTGRVLQVPILEHHVKHGTVTYEDPDT
KEKVTVPVTGGGCKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSSQIAKALGGEPPEGFNYELFLDEKGQKISKSKGN
GLSIEDWLKYASPESLSLFMFQSPRSGKRLFFDVIPRNVDDYFGFLGKYEEQDWKLRLGNPVWHIHAGEPPKVDMPVSFT
MLLNLASASNTEDESVLWGFLNRHVPGVSAETHPKLAELVGYAVKYFHDFVKPNKVFRAPDAVEQEALAKLDAALAALPA
GATADDIQNALYDVARPIERYQDLKAKGATPERPGVSIEWFNTLYQVLLGLGRGPRFGSFVEIYGVAETRELIRKALAGE
LATA

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 62893; Mature: 62762

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPSDTASSAFADPADLAGELKRVAETATAWPFEEARKLVERLKRHPKERGSEEVLFE
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHCCCCCEEEE
TGYGPSGLPHIGTFGEVARTTMVRHAFRVLTEDKVKTRLVAFSDDMDGLRKVPDNVPNKD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCCCCCHH
MLQKALGLPLTKVPDPFGTHDSFGEHNNARLRAFLDAFGFRYEFMSATDCYMSGRFDATL
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHCCCCHHHH
LKVLHHYEKVMNVMLPSLREERAASYSPFLPICPRTGRVLQVPILEHHVKHGTVTYEDPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECHHHHHHHCCCEEEECCCC
TKEKVTVPVTGGGCKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSSQIAKALGGEPPE
CCCEEEEEEECCCEEEEECCCHHEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHCCCCCC
GFNYELFLDEKGQKISKSKGNGLSIEDWLKYASPESLSLFMFQSPRSGKRLFFDVIPRNV
CCCEEEEECCCCCHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCH
DDYFGFLGKYEEQDWKLRLGNPVWHIHAGEPPKVDMPVSFTMLLNLASASNTEDESVLWG
HHHHHHHCCCCCCCCEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
FLNRHVPGVSAETHPKLAELVGYAVKYFHDFVKPNKVFRAPDAVEQEALAKLDAALAALP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCC
AGATADDIQNALYDVARPIERYQDLKAKGATPERPGVSIEWFNTLYQVLLGLGRGPRFGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
FVEIYGVAETRELIRKALAGELATA
EEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAAPSDTASSAFADPADLAGELKRVAETATAWPFEEARKLVERLKRHPKERGSEEVLFE
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHCCCCCEEEE
TGYGPSGLPHIGTFGEVARTTMVRHAFRVLTEDKVKTRLVAFSDDMDGLRKVPDNVPNKD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCCCCCHH
MLQKALGLPLTKVPDPFGTHDSFGEHNNARLRAFLDAFGFRYEFMSATDCYMSGRFDATL
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHCCCCHHHH
LKVLHHYEKVMNVMLPSLREERAASYSPFLPICPRTGRVLQVPILEHHVKHGTVTYEDPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECHHHHHHHCCCEEEECCCC
TKEKVTVPVTGGGCKLQWKPDWAMRWVALGVDYEMAGKDLIDSVKLSSQIAKALGGEPPE
CCCEEEEEEECCCEEEEECCCHHEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHCCCCCC
GFNYELFLDEKGQKISKSKGNGLSIEDWLKYASPESLSLFMFQSPRSGKRLFFDVIPRNV
CCCEEEEECCCCCHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCH
DDYFGFLGKYEEQDWKLRLGNPVWHIHAGEPPKVDMPVSFTMLLNLASASNTEDESVLWG
HHHHHHHCCCCCCCCEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHH
FLNRHVPGVSAETHPKLAELVGYAVKYFHDFVKPNKVFRAPDAVEQEALAKLDAALAALP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCC
AGATADDIQNALYDVARPIERYQDLKAKGATPERPGVSIEWFNTLYQVLLGLGRGPRFGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
FVEIYGVAETRELIRKALAGELATA
EEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]