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The map label for this gene is cobS [H]

Identifier: 154245821

GI number: 154245821

Start: 2114688

End: 2115671

Strand: Direct

Name: cobS [H]

Synonym: Xaut_1877

Alternate gene names: 154245821

Gene position: 2114688-2115671 (Clockwise)

Preceding gene: 154245820

Following gene: 154245822

Centisome position: 39.83

GC content: 64.53

Gene sequence:

>984_bases
ATGAGCGTCACGGAGACCATTGCCCCGACCCCGGACATGAAGGTGTCGGTTCGCCAGACGTTCGGCATCGACATCGACAT
GGAAGTTCCGGCCTTCTCCGAGGCGGACCCCCACGTGCCGGAGCTCGACCCCGACTATCTGTTCGATCGGCCCACCACCC
TTGCCATCCTTGCCGGTTTTGCCCGCAACCGTCGTGTGATGGTGACTGGATACCACGGCACCGGCAAATCCACCCATATC
GAGCAGGTGGCGGCGCGGCTGAACTGGCCGTGCGTGCGCATCAACCTCGACAGCCACATCTCGCGCATCGACCTCATCGG
CAAGGATGCGATCGTGGTGAAGGACGGCCTGCAGGTCACTGAATTCCGCGACGGCATCCTGCCCTGGGCCTACCAGAACA
ATGTCGCCCTGGTGTTCGACGAATATGACGCCGGCCGCCCGGACGTGATGTTCGTGATCCAGCGCGTGCTGGAGAGCTCC
GGCCGCCTGACCCTGCTCGACCAGAGCCGGGTGATCCGCCCCCACCCCGCGTTCCGGCTGTTCGCCACCGCCAACACCAT
CGGCCTCGGCGACACCACCGGCCTTTATCACGGCACCCAGCAGATCAACCAGGCGCAGATGGACCGCTGGTCCATCGTCA
CCTCGCTGAACTATCTGGCCCACGACAAGGAAGTGGACATCGTGCTCGCCAAGGCGAAGCACTTCCAGAACGCCGAGGGG
CGCGACACGGTGAACCGCATGGTGCGCCTCGCCGACCTCACCCGGCAGGCCTTCATGAACGGCGATCTCTCCACCGTCAT
GAGCCCGCGCACGGTGATCACCTGGGCGGAGAATGCGGACATCTTCCGCGATATCGCGTTCGCGCTCCGGGTCACCTTCC
TCAACAAGTGCGACGAGCTGGAGCGGCCGCTGGTGGCCGAGTTCTTCCAGCGCTGCTTCGGCCAGGAGCTGACCGAGAGC
ACCGTGAACGTCGCCTTGTCCTGA

Upstream 100 bases:

>100_bases
ATCCGAAGGATGGCCGGCTTCACGCGGCTGCGGACCGAAACGGCCCCGCACCGGAACGAACACAGGGAAGAGACGCGCCC
GGCGCGTCGACGGAGGAGTT

Downstream 100 bases:

>100_bases
GCCGGGATCTCCCGGCTCCCTTCTCCTGACTTGCGAGACGCCGCCATGGCCCCGACCAACCGCACTCCCGGAAAGGCGCC
GAAGGAAGCCCCCGCCGAGC

Product: cobalt chelatase, pCobS small subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSVTETIAPTPDMKVSVRQTFGIDIDMEVPAFSEADPHVPELDPDYLFDRPTTLAILAGFARNRRVMVTGYHGTGKSTHI
EQVAARLNWPCVRINLDSHISRIDLIGKDAIVVKDGLQVTEFRDGILPWAYQNNVALVFDEYDAGRPDVMFVIQRVLESS
GRLTLLDQSRVIRPHPAFRLFATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTSLNYLAHDKEVDIVLAKAKHFQNAEG
RDTVNRMVRLADLTRQAFMNGDLSTVMSPRTVITWAENADIFRDIAFALRVTFLNKCDELERPLVAEFFQRCFGQELTES
TVNVALS

Sequences:

>Translated_327_residues
MSVTETIAPTPDMKVSVRQTFGIDIDMEVPAFSEADPHVPELDPDYLFDRPTTLAILAGFARNRRVMVTGYHGTGKSTHI
EQVAARLNWPCVRINLDSHISRIDLIGKDAIVVKDGLQVTEFRDGILPWAYQNNVALVFDEYDAGRPDVMFVIQRVLESS
GRLTLLDQSRVIRPHPAFRLFATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTSLNYLAHDKEVDIVLAKAKHFQNAEG
RDTVNRMVRLADLTRQAFMNGDLSTVMSPRTVITWAENADIFRDIAFALRVTFLNKCDELERPLVAEFFQRCFGQELTES
TVNVALS
>Mature_326_residues
SVTETIAPTPDMKVSVRQTFGIDIDMEVPAFSEADPHVPELDPDYLFDRPTTLAILAGFARNRRVMVTGYHGTGKSTHIE
QVAARLNWPCVRINLDSHISRIDLIGKDAIVVKDGLQVTEFRDGILPWAYQNNVALVFDEYDAGRPDVMFVIQRVLESSG
RLTLLDQSRVIRPHPAFRLFATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTSLNYLAHDKEVDIVLAKAKHFQNAEGR
DTVNRMVRLADLTRQAFMNGDLSTVMSPRTVITWAENADIFRDIAFALRVTFLNKCDELERPLVAEFFQRCFGQELTEST
VNVALS

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=212, Percent_Identity=25.4716981132075, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076562, Length=145, Percent_Identity=28.9655172413793, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076560, Length=145, Percent_Identity=28.9655172413793, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36784; Mature: 36653

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTETIAPTPDMKVSVRQTFGIDIDMEVPAFSEADPHVPELDPDYLFDRPTTLAILAGF
CCCCCCCCCCCCCEEEEEEHCCCEEEECCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHH
ARNRRVMVTGYHGTGKSTHIEQVAARLNWPCVRINLDSHISRIDLIGKDAIVVKDGLQVT
HCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEECCCCEEEEECCCEEE
EFRDGILPWAYQNNVALVFDEYDAGRPDVMFVIQRVLESSGRLTLLDQSRVIRPHPAFRL
HHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEE
FATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTSLNYLAHDKEVDIVLAKAKHFQNAEG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCC
RDTVNRMVRLADLTRQAFMNGDLSTVMSPRTVITWAENADIFRDIAFALRVTFLNKCDEL
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ERPLVAEFFQRCFGQELTESTVNVALS
CCCHHHHHHHHHHCHHHHHHHHEEECC
>Mature Secondary Structure 
SVTETIAPTPDMKVSVRQTFGIDIDMEVPAFSEADPHVPELDPDYLFDRPTTLAILAGF
CCCCCCCCCCCCEEEEEEHCCCEEEECCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHH
ARNRRVMVTGYHGTGKSTHIEQVAARLNWPCVRINLDSHISRIDLIGKDAIVVKDGLQVT
HCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEECCCCEEEEECCCEEE
EFRDGILPWAYQNNVALVFDEYDAGRPDVMFVIQRVLESSGRLTLLDQSRVIRPHPAFRL
HHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEE
FATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTSLNYLAHDKEVDIVLAKAKHFQNAEG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCC
RDTVNRMVRLADLTRQAFMNGDLSTVMSPRTVITWAENADIFRDIAFALRVTFLNKCDEL
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ERPLVAEFFQRCFGQELTESTVNVALS
CCCHHHHHHHHHHCHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]