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The map label for this gene is hisS [H]

Identifier: 153951862

GI number: 153951862

Start: 1091702

End: 1092928

Strand: Direct

Name: hisS [H]

Synonym: JJD26997_1247

Alternate gene names: 153951862

Gene position: 1091702-1092928 (Clockwise)

Preceding gene: 153951111

Following gene: 153952578

Centisome position: 59.17

GC content: 30.81

Gene sequence:

>1227_bases
ATGATTAACGCTTTAAAAGGAATGAAAGATTTATTAGATAAAGATGCATATTATTATGAAAAAGTGATTCAAACCTGTGA
AGAAGTAGTTAAAAATTATGGCTTTACTTTTATCAATACACCGCATTTAGAACTTTGTATCCTTTTTAAAAGAAGCGTAG
GAGAAAGTTCTGATATAGTAGGTAAAGAAATGTATGAATTTATCGATAAAGGTGAAAATCATGTTTGCATGCGTCCTGAA
GGAACTGCCGGGGTGGTGCGTGCCTATATAGAAAAAAAACTCGATAAAAACACTAGTGTGAAAAGATGGTTTTATCATGG
TTCCATGTTTCGCTATGAAAGACCTCAAAAAGGACGCTTAAGAGAATTTCATCAATTTGGCGTTGAAAGTTTTGGAAACG
CAAGCGTTTATGAAGATGCAAGTATTATTTTAATGTTAGTAGAAATTTTTTCACGCTTAGATATTAAATTTAAACTGCTG
ATTAACTCTTTAGGTTGTTTAGAATGCATGCCAAAATATCGTGAAAATTTAATACATTTTTTAGACAGCAAAGAAGGCTT
TTGCGAGGATTGTTTGCGTAGAAAAAACTTAAATCCTATTCGTGTTTTAGACTGTAAAAATGAACATTGTCAAAGCTTAC
TTAACGATGCTCCGCTTTTAAATCAAAATTTATGCTCATCTTGTCAAAAAGACTTTGAAATTTTACAAAGCGTTTTAAAA
GAAAATGGAGTGGATTTTGAAGTGGATTCTAAGCTTGTTAGAGGGCTTGATTACTACTCTAAAACGGCTTTTGAATTTAT
TAGCGATGAAATTGGTGCAAAAGCTGCTATTGCAGGGGGTGGAAGATATGATAGACTCATTGAATACCTTGATGGAAAAA
GTGGTTTTGGCATAGGTTTTGCCATGGGCATAGAAAGAATTATAGCTATTTTAGAACAAAAAGAAGAAAAAGTCCAAAGA
GAAGGAATTTATCTTTGTGCTATGGATAAAATTTATATCCAAAAACTTTTGCATATCGCTACAAATTTAAGAAAAGAACA
TAAAGTGCTTTTAAGCTATGAAGCAAGAAAACTAGCTAAGCATCTTGAAAACGCAGATAAAAATAATGCTGAAATTTTTC
TTTGCATGGGAGAAAATGAAGTACAAAATGAAAGTTTGTTTTATAAAAATTTAGTAAAAAAAGAAGAAAAAATGATTAAA
ATTTCAGACTTAAAAAAGGTTTTATGA

Upstream 100 bases:

>100_bases
TGCTTCATTTTTTAAAAGAAAAAATTTCTATAGAAATTTTAACACTTGACGCAAAAGAAAGTAAAGAAAAATTACACCAA
CAAATAAAGGAATTTTTACA

Downstream 100 bases:

>100_bases
TGGATTATGGTATTGATATTTGGGGAAATGAAAATTTTATTATCAAAAATGGTAAAGTTTGTATCAATCATGAGAAAAAA
CCCGCTATTGTTGATATAGT

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MINALKGMKDLLDKDAYYYEKVIQTCEEVVKNYGFTFINTPHLELCILFKRSVGESSDIVGKEMYEFIDKGENHVCMRPE
GTAGVVRAYIEKKLDKNTSVKRWFYHGSMFRYERPQKGRLREFHQFGVESFGNASVYEDASIILMLVEIFSRLDIKFKLL
INSLGCLECMPKYRENLIHFLDSKEGFCEDCLRRKNLNPIRVLDCKNEHCQSLLNDAPLLNQNLCSSCQKDFEILQSVLK
ENGVDFEVDSKLVRGLDYYSKTAFEFISDEIGAKAAIAGGGRYDRLIEYLDGKSGFGIGFAMGIERIIAILEQKEEKVQR
EGIYLCAMDKIYIQKLLHIATNLRKEHKVLLSYEARKLAKHLENADKNNAEIFLCMGENEVQNESLFYKNLVKKEEKMIK
ISDLKKVL

Sequences:

>Translated_408_residues
MINALKGMKDLLDKDAYYYEKVIQTCEEVVKNYGFTFINTPHLELCILFKRSVGESSDIVGKEMYEFIDKGENHVCMRPE
GTAGVVRAYIEKKLDKNTSVKRWFYHGSMFRYERPQKGRLREFHQFGVESFGNASVYEDASIILMLVEIFSRLDIKFKLL
INSLGCLECMPKYRENLIHFLDSKEGFCEDCLRRKNLNPIRVLDCKNEHCQSLLNDAPLLNQNLCSSCQKDFEILQSVLK
ENGVDFEVDSKLVRGLDYYSKTAFEFISDEIGAKAAIAGGGRYDRLIEYLDGKSGFGIGFAMGIERIIAILEQKEEKVQR
EGIYLCAMDKIYIQKLLHIATNLRKEHKVLLSYEARKLAKHLENADKNNAEIFLCMGENEVQNESLFYKNLVKKEEKMIK
ISDLKKVL
>Mature_408_residues
MINALKGMKDLLDKDAYYYEKVIQTCEEVVKNYGFTFINTPHLELCILFKRSVGESSDIVGKEMYEFIDKGENHVCMRPE
GTAGVVRAYIEKKLDKNTSVKRWFYHGSMFRYERPQKGRLREFHQFGVESFGNASVYEDASIILMLVEIFSRLDIKFKLL
INSLGCLECMPKYRENLIHFLDSKEGFCEDCLRRKNLNPIRVLDCKNEHCQSLLNDAPLLNQNLCSSCQKDFEILQSVLK
ENGVDFEVDSKLVRGLDYYSKTAFEFISDEIGAKAAIAGGGRYDRLIEYLDGKSGFGIGFAMGIERIIAILEQKEEKVQR
EGIYLCAMDKIYIQKLLHIATNLRKEHKVLLSYEARKLAKHLENADKNNAEIFLCMGENEVQNESLFYKNLVKKEEKMIK
ISDLKKVL

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI6996014, Length=449, Percent_Identity=26.0579064587973, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI1788861, Length=407, Percent_Identity=38.5749385749386, Blast_Score=291, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI71993693, Length=456, Percent_Identity=23.6842105263158, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71993686, Length=456, Percent_Identity=23.6842105263158, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.21 [H]

Molecular weight: Translated: 47138; Mature: 47138

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINALKGMKDLLDKDAYYYEKVIQTCEEVVKNYGFTFINTPHLELCILFKRSVGESSDIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCHH
GKEMYEFIDKGENHVCMRPEGTAGVVRAYIEKKLDKNTSVKRWFYHGSMFRYERPQKGRL
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCEECCCCCCCHH
REFHQFGVESFGNASVYEDASIILMLVEIFSRLDIKFKLLINSLGCLECMPKYRENLIHF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHH
LDSKEGFCEDCLRRKNLNPIRVLDCKNEHCQSLLNDAPLLNQNLCSSCQKDFEILQSVLK
HCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ENGVDFEVDSKLVRGLDYYSKTAFEFISDEIGAKAAIAGGGRYDRLIEYLDGKSGFGIGF
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCCHHH
AMGIERIIAILEQKEEKVQREGIYLCAMDKIYIQKLLHIATNLRKEHKVLLSYEARKLAK
HHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLENADKNNAEIFLCMGENEVQNESLFYKNLVKKEEKMIKISDLKKVL
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINALKGMKDLLDKDAYYYEKVIQTCEEVVKNYGFTFINTPHLELCILFKRSVGESSDIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCHH
GKEMYEFIDKGENHVCMRPEGTAGVVRAYIEKKLDKNTSVKRWFYHGSMFRYERPQKGRL
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCEECCCCCCCHH
REFHQFGVESFGNASVYEDASIILMLVEIFSRLDIKFKLLINSLGCLECMPKYRENLIHF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHH
LDSKEGFCEDCLRRKNLNPIRVLDCKNEHCQSLLNDAPLLNQNLCSSCQKDFEILQSVLK
HCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ENGVDFEVDSKLVRGLDYYSKTAFEFISDEIGAKAAIAGGGRYDRLIEYLDGKSGFGIGF
HCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCCHHH
AMGIERIIAILEQKEEKVQREGIYLCAMDKIYIQKLLHIATNLRKEHKVLLSYEARKLAK
HHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLENADKNNAEIFLCMGENEVQNESLFYKNLVKKEEKMIKISDLKKVL
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA