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The map label for this gene is speA [H]

Identifier: 153952578

GI number: 153952578

Start: 1092928

End: 1094760

Strand: Direct

Name: speA [H]

Synonym: JJD26997_1248

Alternate gene names: 153952578

Gene position: 1092928-1094760 (Clockwise)

Preceding gene: 153951862

Following gene: 153951619

Centisome position: 59.23

GC content: 32.84

Gene sequence:

>1833_bases
ATGGATTATGGTATTGATATTTGGGGAAATGAAAATTTTATTATCAAAAATGGTAAAGTTTGTATCAATCATGAGAAAAA
ACCCGCTATTGTTGATATAGTTAAAGAATTAAGAGATGATGGATATAAGGGGCCTTTACTTTTAAGATTTCCTCATCTTA
TCCAAAAACAAATTGAAAATATCTACGGAAATTTCAACAAAGCAAAAAAAGAATTTGGCTATAAAGGAGGATTTAACGCT
GTTTATCCTTTAAAGGTCAATCAATACCCTGGTTTTGTAAAAAACCTTGTAAAGCTTGGAAAAGACTATAACTACGGACT
TGAAGCAGGTTCTAAAGCAGAGCTTTTACTCGCTATGGCTTACAATAACGAAGGCGCACCTATTACAGTAAATGGTTTTA
AAGATAGAGAACTTATCAATATAGGCTTTATTGCAGCTGAAATGGGACATAATATCACCTTAACCATAGAAGGGCTTAAT
GAACTTGAAGCTATCATAGACATAGCCAAAGAACGCTTTAAACCTAAACCAAATATAGGCTTACGTGTGCGTTTACATTC
TGCTGGAGTTGGAATTTGGGCAAAAAGCGGTGGGATTAATTCTAAATTTGGACTTACATCCACTGAACTCATAGAAGCAG
TAAATTTGCTTAAAGAAAACAAATTTTTAGAACAATTTACCATGATTCATTTTCATCTAGGCTCACAAATTACCGAAATT
CATCCCTTAAAAAAAGCCTTAAATGAAGCAGGAAATATCTATACAGAACTTAGAAAAATGGGAGCTAAAAACCTAAAAGC
TATCAATCTTGGTGGTGGCTTAGCTGTAGAATACTCGCAATTTAAAAATGAAAAAAACAGAAATTATACCCTAAGAGAAT
ACGCTAACGATGTGATTTTTATCCTAAAAAATATAGCCGAACAAAAAAAAGATTTAGAACCTGATATTTTCATAGAAAGC
GGGCGTTTTGTAGCAGCTAATCATGCTGTTTTAATCGCTCCTGTATTAGAACTTTTTTCCCAAGAATACGCAGAAAACAA
ACTCATACTTAAAAAACAAAACCCAAAACTTATCAACGAACTTTATGATCTTTATAAAAGCATAAAGCCTTCCAATGCTT
TAGAATACCTACACGATAGCATAGATCATTTAGAGAACATTTTAACTCTTTTTGATTTGGGCTATGTGGATTTACAAGAT
CGTTCTAACGCTGAAATTTTAACCCATTTGATTACAAAAAAAGCCATCTTGCTTTTAGGCGATAAGCAAAATCCTGCAGA
TTTACTTGCTATACAGGATGAAGTGCAAGAAAGGTATTTAGTAAATTTTTCGCTCTTTCAAAGCATGCCTGATTTTTGGG
GCTTAGAACAAAATTTCCCTATCATGCCACTTGATCGCTTAGATGAAGAACCGACTCGAAGTGCAAGTATTTGGGATATA
ACCTGTGATAGTGATGGAGAAATTTCATACTCTAAAGACAAGCCTTTATTTTTACACGATGTAGATGTAGAAAAAGAAAA
TTATTTTCTAGGATTTTTCCTTGTAGGTGCCTATCAAGAAGTACTTGGAATGAAACACAATCTTTTTACTCATCCTACTG
AAGCTATTATAAGTATCAATGAGAAAGGCTACGAAGTTGAAGGGATTATAGAAGCACAATCCATACTTGACGCTTTGGAA
GATTTAGACTATGATATACACGCTATCATGGATATACTTAATGAACGCATAAGTAATTCCAAACTTGTAAACGACAAACA
AAAAAAACATATTTTAGGTGAGCTTTATCTTTTCTTAAATGATAATGGTTATTTAAAAAGCATAGGAGTTTAG

Upstream 100 bases:

>100_bases
TGGGAGAAAATGAAGTACAAAATGAAAGTTTGTTTTATAAAAATTTAGTAAAAAAAGAAGAAAAAATGATTAAAATTTCA
GACTTAAAAAAGGTTTTATG

Downstream 100 bases:

>100_bases
ATGAATTTTTGGGGTATTATAAAAGAAGATTTTTCTCAGCCAAATGTACAAGATCCAGCTTTTAATTCTTGTATAGAACT
TTTTTTTAATTACCCTGGAG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MDYGIDIWGNENFIIKNGKVCINHEKKPAIVDIVKELRDDGYKGPLLLRFPHLIQKQIENIYGNFNKAKKEFGYKGGFNA
VYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMAYNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGLN
ELEAIIDIAKERFKPKPNIGLRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKFLEQFTMIHFHLGSQITEI
HPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKNRNYTLREYANDVIFILKNIAEQKKDLEPDIFIES
GRFVAANHAVLIAPVLELFSQEYAENKLILKKQNPKLINELYDLYKSIKPSNALEYLHDSIDHLENILTLFDLGYVDLQD
RSNAEILTHLITKKAILLLGDKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWDI
TCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISINEKGYEVEGIIEAQSILDALE
DLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFLNDNGYLKSIGV

Sequences:

>Translated_610_residues
MDYGIDIWGNENFIIKNGKVCINHEKKPAIVDIVKELRDDGYKGPLLLRFPHLIQKQIENIYGNFNKAKKEFGYKGGFNA
VYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMAYNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGLN
ELEAIIDIAKERFKPKPNIGLRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKFLEQFTMIHFHLGSQITEI
HPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKNRNYTLREYANDVIFILKNIAEQKKDLEPDIFIES
GRFVAANHAVLIAPVLELFSQEYAENKLILKKQNPKLINELYDLYKSIKPSNALEYLHDSIDHLENILTLFDLGYVDLQD
RSNAEILTHLITKKAILLLGDKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWDI
TCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISINEKGYEVEGIIEAQSILDALE
DLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFLNDNGYLKSIGV
>Mature_610_residues
MDYGIDIWGNENFIIKNGKVCINHEKKPAIVDIVKELRDDGYKGPLLLRFPHLIQKQIENIYGNFNKAKKEFGYKGGFNA
VYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMAYNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGLN
ELEAIIDIAKERFKPKPNIGLRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKFLEQFTMIHFHLGSQITEI
HPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKNRNYTLREYANDVIFILKNIAEQKKDLEPDIFIES
GRFVAANHAVLIAPVLELFSQEYAENKLILKKQNPKLINELYDLYKSIKPSNALEYLHDSIDHLENILTLFDLGYVDLQD
RSNAEILTHLITKKAILLLGDKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWDI
TCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISINEKGYEVEGIIEAQSILDALE
DLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFLNDNGYLKSIGV

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=615, Percent_Identity=35.4471544715447, Blast_Score=352, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 69248; Mature: 69248

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYGIDIWGNENFIIKNGKVCINHEKKPAIVDIVKELRDDGYKGPLLLRFPHLIQKQIEN
CCCCEEEECCCEEEEECCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
IYGNFNKAKKEFGYKGGFNAVYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMA
HHCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
YNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGLNELEAIIDIAKERFKPKPNIG
ECCCCCEEEEECCCCCEEEEEEEEEHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCE
LRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKFLEQFTMIHFHLGSQITEI
EEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKNRNYTLREYANDVIF
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHCCCCCCCEEHHHHCCHHHH
ILKNIAEQKKDLEPDIFIESGRFVAANHAVLIAPVLELFSQEYAENKLILKKQNPKLINE
HHHHHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
LYDLYKSIKPSNALEYLHDSIDHLENILTLFDLGYVDLQDRSNAEILTHLITKKAILLLG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCEEEEEE
DKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWDI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHCCCCCCCCCEEEEE
TCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISIN
EECCCCCEEECCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHEEEEC
EKGYEVEGIIEAQSILDALEDLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFLN
CCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEEEEC
DNGYLKSIGV
CCCCEEECCC
>Mature Secondary Structure
MDYGIDIWGNENFIIKNGKVCINHEKKPAIVDIVKELRDDGYKGPLLLRFPHLIQKQIEN
CCCCEEEECCCEEEEECCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
IYGNFNKAKKEFGYKGGFNAVYPLKVNQYPGFVKNLVKLGKDYNYGLEAGSKAELLLAMA
HHCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
YNNEGAPITVNGFKDRELINIGFIAAEMGHNITLTIEGLNELEAIIDIAKERFKPKPNIG
ECCCCCEEEEECCCCCEEEEEEEEEHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCE
LRVRLHSAGVGIWAKSGGINSKFGLTSTELIEAVNLLKENKFLEQFTMIHFHLGSQITEI
EEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HPLKKALNEAGNIYTELRKMGAKNLKAINLGGGLAVEYSQFKNEKNRNYTLREYANDVIF
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEHHHHCCCCCCCEEHHHHCCHHHH
ILKNIAEQKKDLEPDIFIESGRFVAANHAVLIAPVLELFSQEYAENKLILKKQNPKLINE
HHHHHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
LYDLYKSIKPSNALEYLHDSIDHLENILTLFDLGYVDLQDRSNAEILTHLITKKAILLLG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCEEEEEE
DKQNPADLLAIQDEVQERYLVNFSLFQSMPDFWGLEQNFPIMPLDRLDEEPTRSASIWDI
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHCCCCCCCCCEEEEE
TCDSDGEISYSKDKPLFLHDVDVEKENYFLGFFLVGAYQEVLGMKHNLFTHPTEAIISIN
EECCCCCEEECCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHEEEEC
EKGYEVEGIIEAQSILDALEDLDYDIHAIMDILNERISNSKLVNDKQKKHILGELYLFLN
CCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEEEEC
DNGYLKSIGV
CCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA