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The map label for this gene is coaD

Identifier: 153951621

GI number: 153951621

Start: 1090660

End: 1091136

Strand: Direct

Name: coaD

Synonym: JJD26997_1245

Alternate gene names: 153951621

Gene position: 1090660-1091136 (Clockwise)

Preceding gene: 153952584

Following gene: 153951111

Centisome position: 59.11

GC content: 32.7

Gene sequence:

>477_bases
ATGACTTGTTTATATCCTGGGACTTTTGATCCTATTACCAACGGACATTTAGATGTCATAAAACGAGCTTTAAAAATTTT
TGATGAAGTCATCGTTGCTATAGCAAAAAGTGAACATAAAAAACCTTGCTATGATTTAGAAAAACGCAAAGAACTAGCCC
TGCTCGCAACGCAAAATTTAAAAAATGTTAAAATCATTGCTTTTGATAATTTACTTGTAGATTTAGCCAAAGAATTAAAA
GTTAATACTATAATCCGTGGACTTAGAGCAGTGAGTGATTTTGAATACGAATTGCAAATTGGCTATGCAAATCACGCACT
TTGGGAAGATATGGAAACCATTTATCTTATGCCAAGTCTAAAACATGCTTTTATTTCAAGTTCTATTGTTCGCTCTATCG
TAGCACATGGAGGTGATGTAAGTTCTCTTGTTCCAAAAGAAATTCTACCTTTTTTAAAGGATCAATCTTGTATGTAG

Upstream 100 bases:

>100_bases
CAAATGGCTAGATCTTTTAGAAATAAAACACGATTTATATGAAAAATGGCAAAATTTTTAGTTTAAATTTGTTATATTTT
TAAAAAAAATTGGAGCAAAA

Downstream 100 bases:

>100_bases
TTTTTGAAGGTATTGACTGCGTAGGGAAAAGTACGCAAATTTCACTTTTAAAAGAAATTTACAAAGACGCCATTTTCACG
CTCGAACCTGGTGGAACAGA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTCLYPGTFDPITNGHLDVIKRALKIFDEVIVAIAKSEHKKPCYDLEKRKELALLATQNLKNVKIIAFDNLLVDLAKELK
VNTIIRGLRAVSDFEYELQIGYANHALWEDMETIYLMPSLKHAFISSSIVRSIVAHGGDVSSLVPKEILPFLKDQSCM

Sequences:

>Translated_158_residues
MTCLYPGTFDPITNGHLDVIKRALKIFDEVIVAIAKSEHKKPCYDLEKRKELALLATQNLKNVKIIAFDNLLVDLAKELK
VNTIIRGLRAVSDFEYELQIGYANHALWEDMETIYLMPSLKHAFISSSIVRSIVAHGGDVSSLVPKEILPFLKDQSCM
>Mature_157_residues
TCLYPGTFDPITNGHLDVIKRALKIFDEVIVAIAKSEHKKPCYDLEKRKELALLATQNLKNVKIIAFDNLLVDLAKELKV
NTIIRGLRAVSDFEYELQIGYANHALWEDMETIYLMPSLKHAFISSSIVRSIVAHGGDVSSLVPKEILPFLKDQSCM

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=146, Percent_Identity=47.945205479452, Blast_Score=164, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_CAMJ8 (A8FLI0)

Other databases:

- EMBL:   CP000814
- RefSeq:   YP_001482294.1
- ProteinModelPortal:   A8FLI0
- SMR:   A8FLI0
- STRING:   A8FLI0
- GeneID:   5617296
- GenomeReviews:   CP000814_GR
- KEGG:   cju:C8J_0718
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   CJEJ407148:C8J_0718-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17816; Mature: 17685

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCLYPGTFDPITNGHLDVIKRALKIFDEVIVAIAKSEHKKPCYDLEKRKELALLATQNL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
KNVKIIAFDNLLVDLAKELKVNTIIRGLRAVSDFEYELQIGYANHALWEDMETIYLMPSL
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHEEECHHH
KHAFISSSIVRSIVAHGGDVSSLVPKEILPFLKDQSCM
HHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHCCCCCC
>Mature Secondary Structure 
TCLYPGTFDPITNGHLDVIKRALKIFDEVIVAIAKSEHKKPCYDLEKRKELALLATQNL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
KNVKIIAFDNLLVDLAKELKVNTIIRGLRAVSDFEYELQIGYANHALWEDMETIYLMPSL
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHEEECHHH
KHAFISSSIVRSIVAHGGDVSSLVPKEILPFLKDQSCM
HHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA