Click here to switch to the map view.

The map label for this gene is frdC

Identifier: 153948369

GI number: 153948369

Start: 4138185

End: 4138577

Strand: Direct

Name: frdC

Synonym: YpsIP31758_3669

Alternate gene names: 153948369

Gene position: 4138185-4138577 (Clockwise)

Preceding gene: 153949678

Following gene: 153948817

Centisome position: 87.61

GC content: 48.09

Gene sequence:

>393_bases
ATGACAACCAAACGTAAAGCTTATGTTCGTACCATGGCTCCAAACTGGTGGCAACAGCTTGGTTTCTACCGTTTTTATAT
GTTGCGTGAAGGTACATCCATTCCAGCCGTGTGGTTTAGTGTGCTATTGATTTACGGTGTATTCGCACTGAAGAGTGGCC
CCGCAGGGTGGGAAGGGTTTGTCAGCTTCCTGCAAAACCCGCTGGTGCTATTTCTGAATATCCTTACGCTATTTGCCGCG
CTGCTACATACCAAAACCTGGTTTGAGCTGGCGCCGAAAGCGGTCAATATTATCGTTAAAAGCGAAAAAATGGGTCCAGA
GCCAATGATTAAGGCGCTATGGGTTGTGACTGTCGTGGCTAGCGCGATTATCCTGGCTGTCGCCTTACTCTAA

Upstream 100 bases:

>100_bases
CACGTTGATCCCGCGGCGGCTATCCAGCAGGGCAAGATCGACAGTGCGAAAGACTTCATGATCGCCATGCTGAAACCACA
ATAAGGGAGGGGAGACAGTA

Downstream 100 bases:

>100_bases
CCCGGAGGAGAAAAAGATGAATCAAGTCCCTAAACGCTCCGATGAACCGATCTTCTGGGGTCTGTTTGGTGCGGGTGGCA
TGTGGGGTGCAATTATTGCC

Product: fumarate reductase subunit C

Products: fumarate; reduced acceptor

Alternate protein names: Fumarate reductase 15 kDa hydrophobic protein

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MTTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSIPAVWFSVLLIYGVFALKSGPAGWEGFVSFLQNPLVLFLNILTLFAA
LLHTKTWFELAPKAVNIIVKSEKMGPEPMIKALWVVTVVASAIILAVALL

Sequences:

>Translated_130_residues
MTTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSIPAVWFSVLLIYGVFALKSGPAGWEGFVSFLQNPLVLFLNILTLFAA
LLHTKTWFELAPKAVNIIVKSEKMGPEPMIKALWVVTVVASAIILAVALL
>Mature_129_residues
TTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSIPAVWFSVLLIYGVFALKSGPAGWEGFVSFLQNPLVLFLNILTLFAAL
LHTKTWFELAPKAVNIIVKSEKMGPEPMIKALWVVTVVASAIILAVALL

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3029

COG function: function code C; Fumarate reductase subunit C

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdC family

Homologues:

Organism=Escherichia coli, GI1790595, Length=129, Percent_Identity=72.0930232558139, Blast_Score=198, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDC_YERP3 (A7FMZ5)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402623.1
- ProteinModelPortal:   A7FMZ5
- SMR:   A7FMZ5
- STRING:   A7FMZ5
- GeneID:   5385129
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3669
- eggNOG:   COG3029
- HOGENOM:   HBG554089
- OMA:   KMGPEPV
- ProtClustDB:   PRK04987
- BioCyc:   YPSE349747:YPSIP31758_3669-MONOMER
- HAMAP:   MF_00708
- InterPro:   IPR003510
- ProDom:   PD015900

Pfam domain/function: PF02300 Fumarate_red_C

EC number: 1.3.99.1

Molecular weight: Translated: 14679; Mature: 14548

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x20f91230)-; HASH(0x235bfb98)-; HASH(0x23528968)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSIPAVWFSVLLIYGVFALKSGPAGWEGF
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
VSFLQNPLVLFLNILTLFAALLHTKTWFELAPKAVNIIVKSEKMGPEPMIKALWVVTVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SAIILAVALL
HHHHHHHHHH
>Mature Secondary Structure 
TTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSIPAVWFSVLLIYGVFALKSGPAGWEGF
CCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
VSFLQNPLVLFLNILTLFAALLHTKTWFELAPKAVNIIVKSEKMGPEPMIKALWVVTVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SAIILAVALL
HHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA