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The map label for this gene is etfA [H]

Identifier: 152976920

GI number: 152976920

Start: 3288757

End: 3289734

Strand: Reverse

Name: etfA [H]

Synonym: Bcer98_3222

Alternate gene names: 152976920

Gene position: 3289734-3288757 (Counterclockwise)

Preceding gene: 152976921

Following gene: 152976919

Centisome position: 80.49

GC content: 38.75

Gene sequence:

>978_bases
ATGGCTCGTAAAGTATTAGTAATGGGTGAGGTTCGTGATGGATCACTACGTAACGTTTCATTTGAGGCAATCGCAGCAGC
AAAAACAATTGCAGAAGGTGGTGAAGTAGTTGGCCTTCTTATTGGAGAAAGTGTTGCTAGTTTGGCAAGCGAATTGATTC
ATTACGGTGCAGATCGCGTTGTGACAGTTGAAAGTGATACATTAAAATCATATACATCCGATGGTTATGCACAAGCATTT
TTAGCTGTACATGATGAAGAAAAACCAGAGGGGATTGTATTTGGACATACAGCACTTGGAAAAGACTTATCGCCGAAATT
AGCTGCAAAACTAGAAGCAGGACTTGTGTCTGATGTAACTGCTTTAGAAATTGCTGGCGGTAATGTTGTATTCACTCGTC
CAATTTATTCTGGTAAAGCATTTGAGAAGAAAATTGTAACAGATGGTATATTGTTTGCAACGGTGCGCCCAAACAATATT
ACGCCGCTTGAAAAAGATGAGTCGCGTACGGGAGATGTATCATCTATTACAGTTGATGTAAAAGATTTGCGTACGATTAT
TCAAGATGTTGTTCGTAAAACAGCAACAGGTGTAGATCTTTCAGAAGCGAAAGTAATCGTTGCCGGTGGACGTGGAGTGA
AAAGTGAAGATGGTTTTAAACCGTTACAAGAATTAGCTGATGTTTTAGGAGGGGCTGTTGGAGCATCTCGTGGAGCTTGT
GACGCAGAATATTGTGACTATTCATTGCAAATTGGGCAAACAGGTAAAGTTGTTACACCAGATTTATACATTGCATGTGG
TATTTCCGGTGCGATTCAACATTTAGCTGGTATGTCTAACTCAAAAGTAATCGTTGCAATTAATAAAGATCCAGAAGCAA
GTATTTTTAAAGTAGCTGACTATGGCATTGTTGGTGACTTATTTGAAGTTGTACCACTTTTAACAGAGGAGTTTAAAAAG
TTAAAAGTACATTCTTAA

Upstream 100 bases:

>100_bases
CGAGCTGCAAGATCAAGTAAAAGAACTTGTATCATTGCTCCATACAGAAGCAAAAGTAATCTAATAAAATACGAAATTAT
ATATACAGGAGGGAAAATCT

Downstream 100 bases:

>100_bases
TTCGATGATCTTTGCGTTTCAAGTGAATGACCCTTATATATAAGGAAATGTGGGAGATTTCTTGTCTCTCACTTTTTTAT
ATGTATTTCTATATTTTTGT

Product: electron transfer flavoprotein alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MARKVLVMGEVRDGSLRNVSFEAIAAAKTIAEGGEVVGLLIGESVASLASELIHYGADRVVTVESDTLKSYTSDGYAQAF
LAVHDEEKPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVTALEIAGGNVVFTRPIYSGKAFEKKIVTDGILFATVRPNNI
TPLEKDESRTGDVSSITVDVKDLRTIIQDVVRKTATGVDLSEAKVIVAGGRGVKSEDGFKPLQELADVLGGAVGASRGAC
DAEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEASIFKVADYGIVGDLFEVVPLLTEEFKK
LKVHS

Sequences:

>Translated_325_residues
MARKVLVMGEVRDGSLRNVSFEAIAAAKTIAEGGEVVGLLIGESVASLASELIHYGADRVVTVESDTLKSYTSDGYAQAF
LAVHDEEKPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVTALEIAGGNVVFTRPIYSGKAFEKKIVTDGILFATVRPNNI
TPLEKDESRTGDVSSITVDVKDLRTIIQDVVRKTATGVDLSEAKVIVAGGRGVKSEDGFKPLQELADVLGGAVGASRGAC
DAEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEASIFKVADYGIVGDLFEVVPLLTEEFKK
LKVHS
>Mature_324_residues
ARKVLVMGEVRDGSLRNVSFEAIAAAKTIAEGGEVVGLLIGESVASLASELIHYGADRVVTVESDTLKSYTSDGYAQAFL
AVHDEEKPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVTALEIAGGNVVFTRPIYSGKAFEKKIVTDGILFATVRPNNIT
PLEKDESRTGDVSSITVDVKDLRTIIQDVVRKTATGVDLSEAKVIVAGGRGVKSEDGFKPLQELADVLGGAVGASRGACD
AEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEASIFKVADYGIVGDLFEVVPLLTEEFKKL
KVHS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=320, Percent_Identity=41.25, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI189181759, Length=266, Percent_Identity=43.609022556391, Blast_Score=190, Evalue=2e-48,
Organism=Escherichia coli, GI1787990, Length=274, Percent_Identity=34.3065693430657, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1786226, Length=260, Percent_Identity=28.8461538461538, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87082157, Length=235, Percent_Identity=28.936170212766, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=42.8115015974441, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6325261, Length=246, Percent_Identity=42.2764227642276, Blast_Score=171, Evalue=1e-43,
Organism=Drosophila melanogaster, GI17136898, Length=318, Percent_Identity=42.1383647798742, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24652801, Length=318, Percent_Identity=42.1383647798742, Blast_Score=206, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 34226; Mature: 34095

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKVLVMGEVRDGSLRNVSFEAIAAAKTIAEGGEVVGLLIGESVASLASELIHYGADRV
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCEE
VTVESDTLKSYTSDGYAQAFLAVHDEEKPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVT
EEEECHHHHHHCCCCHHEEEEEECCCCCCCCEEEECHHCCCCCCHHHHHHHHHCHHCCCE
ALEIAGGNVVFTRPIYSGKAFEKKIVTDGILFATVRPNNITPLEKDESRTGDVSSITVDV
EEEEECCCEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEH
KDLRTIIQDVVRKTATGVDLSEAKVIVAGGRGVKSEDGFKPLQELADVLGGAVGASRGAC
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
DAEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEASIFKVAD
CHHHCCEEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEC
YGIVGDLFEVVPLLTEEFKKLKVHS
CCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARKVLVMGEVRDGSLRNVSFEAIAAAKTIAEGGEVVGLLIGESVASLASELIHYGADRV
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCEE
VTVESDTLKSYTSDGYAQAFLAVHDEEKPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVT
EEEECHHHHHHCCCCHHEEEEEECCCCCCCCEEEECHHCCCCCCHHHHHHHHHCHHCCCE
ALEIAGGNVVFTRPIYSGKAFEKKIVTDGILFATVRPNNITPLEKDESRTGDVSSITVDV
EEEEECCCEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEH
KDLRTIIQDVVRKTATGVDLSEAKVIVAGGRGVKSEDGFKPLQELADVLGGAVGASRGAC
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
DAEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEASIFKVAD
CHHHCCEEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEC
YGIVGDLFEVVPLLTEEFKKLKVHS
CCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]