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The map label for this gene is nuoH1 [H]

Identifier: 150396120

GI number: 150396120

Start: 968501

End: 969544

Strand: Direct

Name: nuoH1 [H]

Synonym: Smed_0897

Alternate gene names: 150396120

Gene position: 968501-969544 (Clockwise)

Preceding gene: 150396119

Following gene: 150396121

Centisome position: 25.61

GC content: 60.44

Gene sequence:

>1044_bases
ATGGACGCTTTCTTTTCGACCTATGTCTGGCCAACGGCCATCATGATCGGCCAGTCGCTCCTGCTTCTGGTCGCGCTGCT
GCTTTTCATCGCCTATATCCTGCTCGCCGACCGCAAGATCTGGGCGGCCGTTCAGCTTCGCCGCGGTCCTAACGTCGTCG
GCCCCTGGGGGCTGTTCCAGTCCTTTGCCGACCTTCTGAAATTCGTCTTCAAGGAGCCGGTCATTCCGGCCGGCGCCAAC
AAGACGATCTTTCTGCTCGCGCCGCTCGTCTCCGTGACGCTTGCACTCGCCGCCTGGGCGGTGATCCCGCTCAATGCGAA
TTGGGTGATCGCGAACGTCAATGTCGGCATCCTTTTCGTCTTCGCCATATCCTCACTCGAGGTTTATGGCATCATCATGG
GCGGCTGGGCATCCAATTCGAAATATCCGTTCCTCGGCGCATTGCGCTCCGCGGCGCAGATGGTGTCCTATGAGGTCTCG
ATCGGCTTCGTCATTGTCACCGTGCTGCTCTGCGTCGGATCGCTCAATCTGACCGACATCGTGATCGCGCAGAACGACGG
CCTCGGTACCATGCTGGGCCTGCCGGCGTCCTTCCTCGACTGGCACTGGCTGTCGCTCTTCCCGATGTTCATCATCTTCT
TCATCTCGGCCCTGGCCGAGACGAACCGTCCGCCCTTCGACCTCCCGGAAGCCGAGTCGGAACTGGTCGCCGGCTTCATG
GTCGAATACGGCTCCACCCCGTACATGATGTTCATGCTCGGCGAATACGCGGCGATCTGCCTGATGTGTGCCCTGACCAC
GATCCTGTTCCTCGGCGGCTGGCTGCCACCGGTCGACATCTGGATCCTGAACTGGGTCCCGGGGATCATCTGGTTCGTGC
TGAAGGCCTCGCTGGTGTTCTTCATGTTCGCGATGGTGAAGGCCTTCGTACCGCGCTACCGCTACGACCAGCTGATGCGT
CTCGGCTGGAAGGTCTTCCTGCCGCTCTCGCTGGCGATGGTCGTCATCGTCGCATTCGTTCTGAAGCTGATGGGTTGGGC
ATGA

Upstream 100 bases:

>100_bases
ACCCGATAGCGCGCGCGTCCGCCGTCATGGCCGAGTGCTCGGCCTTGGCGCGCAACAATTTCAAAGCTGCCGCGGAATGA
GCGCGAGGGAATAGAGCATC

Downstream 100 bases:

>100_bases
TGGCCGCTCAAGCTTCGCTGCATACCGCCGGTTTTTCCGAAACCGGCAAGTTTGGAGGTTAATGATGGCCGGTCTTTCGA
ACGCCGTCAGCTCGCTGTTC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H 1; NDH-1 subunit H 1 [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MDAFFSTYVWPTAIMIGQSLLLLVALLLFIAYILLADRKIWAAVQLRRGPNVVGPWGLFQSFADLLKFVFKEPVIPAGAN
KTIFLLAPLVSVTLALAAWAVIPLNANWVIANVNVGILFVFAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVS
IGFVIVTVLLCVGSLNLTDIVIAQNDGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
VEYGSTPYMMFMLGEYAAICLMCALTTILFLGGWLPPVDIWILNWVPGIIWFVLKASLVFFMFAMVKAFVPRYRYDQLMR
LGWKVFLPLSLAMVVIVAFVLKLMGWA

Sequences:

>Translated_347_residues
MDAFFSTYVWPTAIMIGQSLLLLVALLLFIAYILLADRKIWAAVQLRRGPNVVGPWGLFQSFADLLKFVFKEPVIPAGAN
KTIFLLAPLVSVTLALAAWAVIPLNANWVIANVNVGILFVFAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVS
IGFVIVTVLLCVGSLNLTDIVIAQNDGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
VEYGSTPYMMFMLGEYAAICLMCALTTILFLGGWLPPVDIWILNWVPGIIWFVLKASLVFFMFAMVKAFVPRYRYDQLMR
LGWKVFLPLSLAMVVIVAFVLKLMGWA
>Mature_347_residues
MDAFFSTYVWPTAIMIGQSLLLLVALLLFIAYILLADRKIWAAVQLRRGPNVVGPWGLFQSFADLLKFVFKEPVIPAGAN
KTIFLLAPLVSVTLALAAWAVIPLNANWVIANVNVGILFVFAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVS
IGFVIVTVLLCVGSLNLTDIVIAQNDGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
VEYGSTPYMMFMLGEYAAICLMCALTTILFLGGWLPPVDIWILNWVPGIIWFVLKASLVFFMFAMVKAFVPRYRYDQLMR
LGWKVFLPLSLAMVVIVAFVLKLMGWA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=306, Percent_Identity=42.483660130719, Blast_Score=238, Evalue=4e-63,
Organism=Escherichia coli, GI1788618, Length=339, Percent_Identity=38.6430678466077, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38512; Mature: 38512

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAFFSTYVWPTAIMIGQSLLLLVALLLFIAYILLADRKIWAAVQLRRGPNVVGPWGLFQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
SFADLLKFVFKEPVIPAGANKTIFLLAPLVSVTLALAAWAVIPLNANWVIANVNVGILFV
HHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHH
FAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLCVGSLNLTDI
HHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VIAQNDGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
EEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
VEYGSTPYMMFMLGEYAAICLMCALTTILFLGGWLPPVDIWILNWVPGIIWFVLKASLVF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FMFAMVKAFVPRYRYDQLMRLGWKVFLPLSLAMVVIVAFVLKLMGWA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDAFFSTYVWPTAIMIGQSLLLLVALLLFIAYILLADRKIWAAVQLRRGPNVVGPWGLFQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
SFADLLKFVFKEPVIPAGANKTIFLLAPLVSVTLALAAWAVIPLNANWVIANVNVGILFV
HHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHH
FAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLCVGSLNLTDI
HHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VIAQNDGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
EEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
VEYGSTPYMMFMLGEYAAICLMCALTTILFLGGWLPPVDIWILNWVPGIIWFVLKASLVF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FMFAMVKAFVPRYRYDQLMRLGWKVFLPLSLAMVVIVAFVLKLMGWA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA