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The map label for this gene is nuoI1 [H]

Identifier: 150396121

GI number: 150396121

Start: 969609

End: 970100

Strand: Direct

Name: nuoI1 [H]

Synonym: Smed_0898

Alternate gene names: 150396121

Gene position: 969609-970100 (Clockwise)

Preceding gene: 150396120

Following gene: 150396122

Centisome position: 25.64

GC content: 60.77

Gene sequence:

>492_bases
ATGGCCGGTCTTTCGAACGCCGTCAGCTCGCTGTTCCTCAAGGAATTCGTCGGCGCATTCCTTCTGTCGATGCGCTATTT
CTTCCGGCCGAAGGCGACCTTGAATTACCCTTACGAGAAGGGCCCGATCAGTCCGCGCTTTCGCGGCGAGCACGCATTGC
GCCGTTATCCGAACGGCGAAGAGCGTTGCATCGCCTGCAAACTGTGCGAGGCGATCTGTCCTGCCCAGGCCATTACCATC
GAGGCCGGGCCGCGCCGCAACGACGGCACGCGCCGCACGGTGCGCTACGATATCGACATGGTGAAGTGCATCTATTGCGG
CTTCTGTCAGGAAGCCTGTCCGGTGGATGCGATCGTCGAGGGGCCGAATTTCGAATTCTCGACCGAGACGCGCGAAGAGC
TCTACTACGACAAGGAGAAGCTGCTCGCCAACGGTGACCGGTGGGAGCGTGAAATCGCGCGCAACATTGCGATGGACTCG
CCCTACCGCTGA

Upstream 100 bases:

>100_bases
GTCGCATTCGTTCTGAAGCTGATGGGTTGGGCATGATGGCCGCTCAAGCTTCGCTGCATACCGCCGGTTTTTCCGAAACC
GGCAAGTTTGGAGGTTAATG

Downstream 100 bases:

>100_bases
GGCCAGTCGCTGAACGAAGCATTGCGCCGCTTGATCGAGACGGTGCATGCAAAACGGGTTTGGGCATCAGCCGGACAGGT
GGTCCGGCTTTGCCTCATGG

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I 1; NDH-1 subunit I 1 [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MAGLSNAVSSLFLKEFVGAFLLSMRYFFRPKATLNYPYEKGPISPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITI
EAGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFSTETREELYYDKEKLLANGDRWEREIARNIAMDS
PYR

Sequences:

>Translated_163_residues
MAGLSNAVSSLFLKEFVGAFLLSMRYFFRPKATLNYPYEKGPISPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITI
EAGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFSTETREELYYDKEKLLANGDRWEREIARNIAMDS
PYR
>Mature_162_residues
AGLSNAVSSLFLKEFVGAFLLSMRYFFRPKATLNYPYEKGPISPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIE
AGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFSTETREELYYDKEKLLANGDRWEREIARNIAMDSP
YR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=157, Percent_Identity=74.5222929936306, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI1788617, Length=142, Percent_Identity=38.0281690140845, Blast_Score=99, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17555194, Length=164, Percent_Identity=68.2926829268293, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI17864306, Length=157, Percent_Identity=73.2484076433121, Blast_Score=248, Evalue=2e-66,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18759; Mature: 18627

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLSNAVSSLFLKEFVGAFLLSMRYFFRPKATLNYPYEKGPISPRFRGEHALRRYPNGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
ERCIACKLCEAICPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVE
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEC
GPNFEFSTETREELYYDKEKLLANGDRWEREIARNIAMDSPYR
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AGLSNAVSSLFLKEFVGAFLLSMRYFFRPKATLNYPYEKGPISPRFRGEHALRRYPNGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
ERCIACKLCEAICPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVE
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEC
GPNFEFSTETREELYYDKEKLLANGDRWEREIARNIAMDSPYR
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]