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The map label for this gene is ctaA [H]

Identifier: 150396081

GI number: 150396081

Start: 917444

End: 918547

Strand: Direct

Name: ctaA [H]

Synonym: Smed_0858

Alternate gene names: 150396081

Gene position: 917444-918547 (Clockwise)

Preceding gene: 150396077

Following gene: 150396087

Centisome position: 24.26

GC content: 62.23

Gene sequence:

>1104_bases
ATGGCTCATGCCGAGTTGGCAACAGAACAGACGCTGCTGAGAGAAATCGGCAGAACCGAGCGCAACCGCCGGCACATCCG
CGGCTGGCTTGCCGTCGTTCTCTTTGCCTTGTTTGCGCTTGTGCTCGTGGGCGGAGCGACGCGCCTGACCGAATCCGGCC
TTTCCATCACCGAGTGGAAACCGGTGCACGGCGTCATCCCGCCCCTGTCTGCGCAGGAGTGGGAAGAGGAATTCCGTCTC
TATCAGCGCATTCCGCAATATGAGCAGATCAACAAAGGCATGACCGTCGACGATTTCAAGACCATTTTCTGGTGGGAATG
GGCGCACCGGCTGCTTGCGCGCGGCATCGGCGTGATCTTCGCTCTGCCGCTCTTCTTCTTCTGGGTCACCGGGCGGGTGG
AGCGTCGCCTGCGGCTGCCGCTTCTTGCAATTCTGGCGCTCGGCGGCTTGCAGGGCTTTATCGGCTGGTGGATGGTTTCC
TCGGGTCTCGCGGAACGGACCGCCGTCAGCCAGTACCGGCTCGCCACCCATCTGACCATCGCCTGCGTGATCTTCGCCGC
CTGCATGTGGATCTATCGGGGGCTATGTCCGCATTCCGACGACGCGCCTCCGACCAAAGCCTCACAAAAGATGGCGGCGG
TCATAGCGATCTTCAGTCTCTTCCAGATCTATCTGGGAGCGATCGTTGCAGGTCTCGACGCGGGTCTGAGCTATAACACC
TGGCCGCTGATGGACGGTGCGATCGTGCCGGGCGGCCTGTTCGTGCAGCAGCCCGCCTGGATCAATCTCTTCGAAAATCC
GAAGACGGTGCAGTTCGTCCACCGCCTCGGCGCCTATCTTCTGCTCGCATTGGTGCTTTGGCACATGATCGCGGCCTTGC
GCTCCGCGCCGGAAACCACCCACGCGCGCCGCTCGGTGCTGCTGTTTGCACTGGTGGTCGTGCAGGCGGCCATCGGCATC
ACCACGCTGCTTCTGCAGGTCCCCATCGGTTGGGGCGTGCTGCATCAGGGCGGCGCGCTCGTGGTACTCGGTTTTGCGAT
TGCCCACTGGCGCGGTTTCGTAGGCGCCTATCCGAAGGATACGGCAATCGAAGTTCGCGCTTGA

Upstream 100 bases:

>100_bases
TTGCACGGCGCTCTGGTGCAAATCAACGGCTTTGAGGGCGTCCCGGCCGGCAAACCCGGCAAAGCGGTACCCGTTTTGCG
GTGACAGATGAGGAAGTGCC

Downstream 100 bases:

>100_bases
TCTTGATGCTCTGTGGTTAAGATAGACAGAAGCCCCGGAAGGGAGGCTGCCGGGGCTTCTGTCTGCCGGGTCTCAGGCGG
AAAGCATCAGGTCCATGTTC

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MAHAELATEQTLLREIGRTERNRRHIRGWLAVVLFALFALVLVGGATRLTESGLSITEWKPVHGVIPPLSAQEWEEEFRL
YQRIPQYEQINKGMTVDDFKTIFWWEWAHRLLARGIGVIFALPLFFFWVTGRVERRLRLPLLAILALGGLQGFIGWWMVS
SGLAERTAVSQYRLATHLTIACVIFAACMWIYRGLCPHSDDAPPTKASQKMAAVIAIFSLFQIYLGAIVAGLDAGLSYNT
WPLMDGAIVPGGLFVQQPAWINLFENPKTVQFVHRLGAYLLLALVLWHMIAALRSAPETTHARRSVLLFALVVVQAAIGI
TTLLLQVPIGWGVLHQGGALVVLGFAIAHWRGFVGAYPKDTAIEVRA

Sequences:

>Translated_367_residues
MAHAELATEQTLLREIGRTERNRRHIRGWLAVVLFALFALVLVGGATRLTESGLSITEWKPVHGVIPPLSAQEWEEEFRL
YQRIPQYEQINKGMTVDDFKTIFWWEWAHRLLARGIGVIFALPLFFFWVTGRVERRLRLPLLAILALGGLQGFIGWWMVS
SGLAERTAVSQYRLATHLTIACVIFAACMWIYRGLCPHSDDAPPTKASQKMAAVIAIFSLFQIYLGAIVAGLDAGLSYNT
WPLMDGAIVPGGLFVQQPAWINLFENPKTVQFVHRLGAYLLLALVLWHMIAALRSAPETTHARRSVLLFALVVVQAAIGI
TTLLLQVPIGWGVLHQGGALVVLGFAIAHWRGFVGAYPKDTAIEVRA
>Mature_366_residues
AHAELATEQTLLREIGRTERNRRHIRGWLAVVLFALFALVLVGGATRLTESGLSITEWKPVHGVIPPLSAQEWEEEFRLY
QRIPQYEQINKGMTVDDFKTIFWWEWAHRLLARGIGVIFALPLFFFWVTGRVERRLRLPLLAILALGGLQGFIGWWMVSS
GLAERTAVSQYRLATHLTIACVIFAACMWIYRGLCPHSDDAPPTKASQKMAAVIAIFSLFQIYLGAIVAGLDAGLSYNTW
PLMDGAIVPGGLFVQQPAWINLFENPKTVQFVHRLGAYLLLALVLWHMIAALRSAPETTHARRSVLLFALVVVQAAIGIT
TLLLQVPIGWGVLHQGGALVVLGFAIAHWRGFVGAYPKDTAIEVRA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921985, Length=329, Percent_Identity=38.2978723404255, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI17921987, Length=300, Percent_Identity=37.6666666666667, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17536069, Length=346, Percent_Identity=38.4393063583815, Blast_Score=211, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6320989, Length=374, Percent_Identity=37.9679144385027, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI19922860, Length=356, Percent_Identity=36.7977528089888, Blast_Score=198, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: NA

Molecular weight: Translated: 40880; Mature: 40748

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEECC
>Mature Secondary Structure 
AHAELATEQTLLREIGRTERNRRHIRGWLAVVLFALFALVLVGGATRLTESGLSITEWK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
PVHGVIPPLSAQEWEEEFRLYQRIPQYEQINKGMTVDDFKTIFWWEWAHRLLARGIGVIF
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALPLFFFWVTGRVERRLRLPLLAILALGGLQGFIGWWMVSSGLAERTAVSQYRLATHLTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACVIFAACMWIYRGLCPHSDDAPPTKASQKMAAVIAIFSLFQIYLGAIVAGLDAGLSYNT
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WPLMDGAIVPGGLFVQQPAWINLFENPKTVQFVHRLGAYLLLALVLWHMIAALRSAPETT
CCCCCCCCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HARRSVLLFALVVVQAAIGITTLLLQVPIGWGVLHQGGALVVLGFAIAHWRGFVGAYPKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
TAIEVRA
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]