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The map label for this gene is purE [H]

Identifier: 150009757

GI number: 150009757

Start: 3836601

End: 3837107

Strand: Direct

Name: purE [H]

Synonym: BDI_3172

Alternate gene names: 150009757

Gene position: 3836601-3837107 (Clockwise)

Preceding gene: 150009756

Following gene: 150009758

Centisome position: 79.74

GC content: 50.89

Gene sequence:

>507_bases
ATGACACCTGTTGTAAGTATTATCATGGGTAGTACCTCGGATCTACCCGTTATGGAGAAGGCGGCTAAGTTCTTGGATGA
GATGGAGATCCCGTTCGAGATGCATGCTCTATCCGCACACCGTACTCCCGCTGAGGTGGAGGCTTTCGCCAAAGGAGCTA
AAGGACGTGGAATCAAGGTTATCATCGCCGCTGCCGGAATGGCCGCTCATCTTTGCGGTGTGATCGCTTCCATGACGACG
GTTCCCGTGATCGGCGTGCCTATTAACTCTACGCTGGACGGTATGGATGCCTTGTTGGCTATCGTACAGATGCCTCCGGG
AATCCCTGTGGCTACTGTCGGCATCAATGGCGCTTTGAACGCTGGTATCCTTGCGGTGCAGATGCTTGCCGTCGGCGACG
AGCAACTTCAGGAGAAGCTATCCGCTTATAAGGAGGATTTGAAGAAGAAAATCGTGAAGGCTAACGAGGAGTTGGCTAAG
GTTTCTTTTAAATACAAAACTAATTAA

Upstream 100 bases:

>100_bases
ATGGTAAAGGTTGGTTAATCAAGATTTCTCTTACGGACGCTTCTGAGTTGGAGGAACTATTATCCGCTGAAGACTATCAA
AAATTAATCGCTAAATAAGA

Downstream 100 bases:

>100_bases
TTGAAAGTTGAAAGTTGAGAATTGAAAATTAAGGAGAAAGTCTCTCTTTAGGTTTTCAGTTCTCAACACTCATTCTCAAT
TTTCAATTCTCAATTTTCAA

Product: phosphoribosylaminoimidazole carboxylase subunit PurE

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTPVVSIIMGSTSDLPVMEKAAKFLDEMEIPFEMHALSAHRTPAEVEAFAKGAKGRGIKVIIAAAGMAAHLCGVIASMTT
VPVIGVPINSTLDGMDALLAIVQMPPGIPVATVGINGALNAGILAVQMLAVGDEQLQEKLSAYKEDLKKKIVKANEELAK
VSFKYKTN

Sequences:

>Translated_168_residues
MTPVVSIIMGSTSDLPVMEKAAKFLDEMEIPFEMHALSAHRTPAEVEAFAKGAKGRGIKVIIAAAGMAAHLCGVIASMTT
VPVIGVPINSTLDGMDALLAIVQMPPGIPVATVGINGALNAGILAVQMLAVGDEQLQEKLSAYKEDLKKKIVKANEELAK
VSFKYKTN
>Mature_167_residues
TPVVSIIMGSTSDLPVMEKAAKFLDEMEIPFEMHALSAHRTPAEVEAFAKGAKGRGIKVIIAAAGMAAHLCGVIASMTTV
PVIGVPINSTLDGMDALLAIVQMPPGIPVATVGINGALNAGILAVQMLAVGDEQLQEKLSAYKEDLKKKIVKANEELAKV
SFKYKTN

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=110, Percent_Identity=50.9090909090909, Blast_Score=108, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324702, Length=157, Percent_Identity=51.5923566878981, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17642; Mature: 17511

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVVSIIMGSTSDLPVMEKAAKFLDEMEIPFEMHALSAHRTPAEVEAFAKGAKGRGIKV
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCEEE
IIAAAGMAAHLCGVIASMTTVPVIGVPINSTLDGMDALLAIVQMPPGIPVATVGINGALN
EEECCCHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHH
AGILAVQMLAVGDEQLQEKLSAYKEDLKKKIVKANEELAKVSFKYKTN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEECC
>Mature Secondary Structure 
TPVVSIIMGSTSDLPVMEKAAKFLDEMEIPFEMHALSAHRTPAEVEAFAKGAKGRGIKV
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCEEE
IIAAAGMAAHLCGVIASMTTVPVIGVPINSTLDGMDALLAIVQMPPGIPVATVGINGALN
EEECCCHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHH
AGILAVQMLAVGDEQLQEKLSAYKEDLKKKIVKANEELAKVSFKYKTN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]