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The map label for this gene is htpG [H]

Identifier: 150005807

GI number: 150005807

Start: 4135770

End: 4137815

Strand: Direct

Name: htpG [H]

Synonym: BVU_3300

Alternate gene names: 150005807

Gene position: 4135770-4137815 (Clockwise)

Preceding gene: 150005806

Following gene: 150005808

Centisome position: 80.1

GC content: 40.62

Gene sequence:

>2046_bases
ATGCAAAAAGGAAATATTGGGGTAACCACTGAGAACATTTTCCCCATCATTAAAAAGTTCTTATACAGTGATCATGAAAT
ATTCCTCCGTGAATTAGTTTCTAATGCAGTAGATGCCACACAGAAGCTGAAAACCCTTGCATCTAAAGGTGAATTCAAAG
GAGAGATGGGAGATCTTACCATTAAAGTAAGCTTAGGAAAAGATACCATCACCATTTCCGACCGGGGTATCGGACTTACA
GCCGAAGAGATCGACAAATATATCAATCAGATAGCTTTTTCAGGTGCTAACGACTTCCTTGAAAAATATAAAGATGATGC
CAATGCCATCATCGGACACTTTGGTCTGGGTTTCTATTCTGCCTTCATGGTAGCCAAAAAAGTGGAAATCATCACAAAAT
CCCACCAAGAAGGAGCACAAGCTGTGAAATGGACTTGCGACGGAAGCCCTGAGTTCACTATCGAAAACGTTGAAAAAGAA
AGCCGCGGATCGGATATTATCCTTTATATAGATGATGACTGCAAGGAATTTCTGGAAGAAACACGTATTTCTTCATTGCT
GACTAAATATTGCCGCTTCCTTCCTATCCCCATTGCATTCGGCAAAAAGAAAGAATGGAAAGATGGAAAGCAGGTTGAAA
CAAACGAAGACAACGTAATCAACGAAACCTATCCTTTATGGACACGCAAACCGGTAGAGCTGAAAGACGAAGATTATAAG
AAATTCTATCGGGAGTTATATCCTATGGCAGACGAACCTCTGTTCTGGATCCACCTGAATGTGGATTATCCGTTCAATCT
GACAGGTATTCTGTACTTCCCGAAAGTGAAGAGCAACATTGAATTACAAAAAAACAAAATCCAACTTTACTGCAACCAGG
TCTATGTCACCGACTCGGTAGAAGGTATTGTTCCAGACTTCCTGACCCTGTTACACGGAGTGATTGACTCACCGGATATC
CCGTTGAACGTATCCCGTTCTTACTTGCAGAGCGATTCCAACGTGAAGAAAATCTCCACTTATATTTCTAAGAAAGTATC
AGACCGCCTGCAAGCCATTTTTAAGAATGACCGCAAAGAATTCGAGGAGAAATGGGATGATTTGAAGATTTTCATCAACT
ACGGCATGTTGACTCAAGAAGATTTCTACGAAAAGGCTAATAAATTTGCTCTGCTGAAAGACACAGATGACAAATATTAC
ACTTACGAAGAATACCAAAGCTTGATCAAAGATAACCAAACAGATAAGGACGGCAACTTGATTTATCTGTATGCTACCCA
TGCAGACGAACAATACAGCTACATTGATGCGGCCAAAAACAAAGGCTACAACGTATTGTTAATGGATGGTCAGCTGGATG
TAGCCATGGTAAGTATGCTCGAGCAGAAATTTGAAAAGAGCCGCTTCACCCGTGTGGACAGTGATGTAATTGACCACCTG
ATTGCTAAAGAAGAGCGCAAAGATGCCAGTTTGGAAGTTGGCCAACGCGATATTCTATCTTCCGTATTCCGCAGTCAGTT
ACCACAGATGAAGAAAGTGGAATTCAATGTGGAAACACAATCTTTAGGCGAGACAGGAACTCCTATCATGATTACCCAAA
GTGAATATATGCGCCGTATGAAAGAAATGGCCAATATCCAGGCAGGTATGAGTTTCTATGGAGAAATGCCGGATATGTTT
AACTTGGTTCTGAATGTCGACCACAAACTGGTGAAACAAGTTTTGAATGATGCGGACAACTCTTGCAAAGCTGCTCTTGA
ACCTATTGAAGCTGAAATGACCAGTCTGAATAAACGTCACGACGAACTTCACAAAGCACAGGAAGGTAAAAAAGCTGATG
AAATACCTCAAGCAGAAAAAGATGAATTAAGTAATGTTGAGAAAAAGTTGGCCGATGAAAAGACCAAGAAAGAAGCTGTT
TTAGGTGAATACGCAGGTGGTAACAAAGTAATCCGCCAATTGATTGACCTTGCTCTGTTACAAAACAACATGTTGAAAGG
TGAAGCTTTGACAAACTTTGTAAAACGCAGTATCGAACTGATTTAA

Upstream 100 bases:

>100_bases
ATGTCAGATATCACTGTATCTGGCATTTTTTTTGCCCATCATCCAACAAAAAGACGATTCAAACGTATATATAACATAAT
AACTTAAAACCATAAATAGT

Downstream 100 bases:

>100_bases
CAAATCTATCACATTTTGCTATCAAAAGCGTCGGGAAGTTCATTTCCGGCGCTTTTTTATTCTAAAAAACGATTGGAAAC
GAAGATTTCTTTCTATATTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLASKGEFKGEMGDLTIKVSLGKDTITISDRGIGLT
AEEIDKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYSAFMVAKKVEIITKSHQEGAQAVKWTCDGSPEFTIENVEKE
SRGSDIILYIDDDCKEFLEETRISSLLTKYCRFLPIPIAFGKKKEWKDGKQVETNEDNVINETYPLWTRKPVELKDEDYK
KFYRELYPMADEPLFWIHLNVDYPFNLTGILYFPKVKSNIELQKNKIQLYCNQVYVTDSVEGIVPDFLTLLHGVIDSPDI
PLNVSRSYLQSDSNVKKISTYISKKVSDRLQAIFKNDRKEFEEKWDDLKIFINYGMLTQEDFYEKANKFALLKDTDDKYY
TYEEYQSLIKDNQTDKDGNLIYLYATHADEQYSYIDAAKNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDHL
IAKEERKDASLEVGQRDILSSVFRSQLPQMKKVEFNVETQSLGETGTPIMITQSEYMRRMKEMANIQAGMSFYGEMPDMF
NLVLNVDHKLVKQVLNDADNSCKAALEPIEAEMTSLNKRHDELHKAQEGKKADEIPQAEKDELSNVEKKLADEKTKKEAV
LGEYAGGNKVIRQLIDLALLQNNMLKGEALTNFVKRSIELI

Sequences:

>Translated_681_residues
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLASKGEFKGEMGDLTIKVSLGKDTITISDRGIGLT
AEEIDKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYSAFMVAKKVEIITKSHQEGAQAVKWTCDGSPEFTIENVEKE
SRGSDIILYIDDDCKEFLEETRISSLLTKYCRFLPIPIAFGKKKEWKDGKQVETNEDNVINETYPLWTRKPVELKDEDYK
KFYRELYPMADEPLFWIHLNVDYPFNLTGILYFPKVKSNIELQKNKIQLYCNQVYVTDSVEGIVPDFLTLLHGVIDSPDI
PLNVSRSYLQSDSNVKKISTYISKKVSDRLQAIFKNDRKEFEEKWDDLKIFINYGMLTQEDFYEKANKFALLKDTDDKYY
TYEEYQSLIKDNQTDKDGNLIYLYATHADEQYSYIDAAKNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDHL
IAKEERKDASLEVGQRDILSSVFRSQLPQMKKVEFNVETQSLGETGTPIMITQSEYMRRMKEMANIQAGMSFYGEMPDMF
NLVLNVDHKLVKQVLNDADNSCKAALEPIEAEMTSLNKRHDELHKAQEGKKADEIPQAEKDELSNVEKKLADEKTKKEAV
LGEYAGGNKVIRQLIDLALLQNNMLKGEALTNFVKRSIELI
>Mature_681_residues
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLASKGEFKGEMGDLTIKVSLGKDTITISDRGIGLT
AEEIDKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYSAFMVAKKVEIITKSHQEGAQAVKWTCDGSPEFTIENVEKE
SRGSDIILYIDDDCKEFLEETRISSLLTKYCRFLPIPIAFGKKKEWKDGKQVETNEDNVINETYPLWTRKPVELKDEDYK
KFYRELYPMADEPLFWIHLNVDYPFNLTGILYFPKVKSNIELQKNKIQLYCNQVYVTDSVEGIVPDFLTLLHGVIDSPDI
PLNVSRSYLQSDSNVKKISTYISKKVSDRLQAIFKNDRKEFEEKWDDLKIFINYGMLTQEDFYEKANKFALLKDTDDKYY
TYEEYQSLIKDNQTDKDGNLIYLYATHADEQYSYIDAAKNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDHL
IAKEERKDASLEVGQRDILSSVFRSQLPQMKKVEFNVETQSLGETGTPIMITQSEYMRRMKEMANIQAGMSFYGEMPDMF
NLVLNVDHKLVKQVLNDADNSCKAALEPIEAEMTSLNKRHDELHKAQEGKKADEIPQAEKDELSNVEKKLADEKTKKEAV
LGEYAGGNKVIRQLIDLALLQNNMLKGEALTNFVKRSIELI

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=597, Percent_Identity=29.1457286432161, Blast_Score=242, Evalue=7e-64,
Organism=Homo sapiens, GI4507677, Length=639, Percent_Identity=27.0735524256651, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI153792590, Length=194, Percent_Identity=38.1443298969072, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI154146191, Length=197, Percent_Identity=36.5482233502538, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI20149594, Length=194, Percent_Identity=37.1134020618557, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI1786679, Length=583, Percent_Identity=31.7324185248714, Blast_Score=256, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI115535205, Length=464, Percent_Identity=29.0948275862069, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI115535167, Length=393, Percent_Identity=30.7888040712468, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17542208, Length=623, Percent_Identity=27.6083467094703, Blast_Score=196, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17559162, Length=498, Percent_Identity=28.5140562248996, Blast_Score=192, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6325016, Length=501, Percent_Identity=29.5409181636727, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6323840, Length=497, Percent_Identity=29.1750503018109, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24586016, Length=530, Percent_Identity=32.4528301886792, Blast_Score=261, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21357739, Length=516, Percent_Identity=30.8139534883721, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI17647529, Length=638, Percent_Identity=26.6457680250784, Blast_Score=207, Evalue=2e-53,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 78179; Mature: 78179

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLASKGEFKGEMGDLT
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
IKVSLGKDTITISDRGIGLTAEEIDKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYS
EEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHH
AFMVAKKVEIITKSHQEGAQAVKWTCDGSPEFTIENVEKESRGSDIILYIDDDCKEFLEE
HHHHHHHHHHHHHCHHCCCCEEEEEECCCCCEEEECCHHHCCCCEEEEEECHHHHHHHHH
TRISSLLTKYCRFLPIPIAFGKKKEWKDGKQVETNEDNVINETYPLWTRKPVELKDEDYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
KFYRELYPMADEPLFWIHLNVDYPFNLTGILYFPKVKSNIELQKNKIQLYCNQVYVTDSV
HHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCEEECCEEEEEEEEEEEECCC
EGIVPDFLTLLHGVIDSPDIPLNVSRSYLQSDSNVKKISTYISKKVSDRLQAIFKNDRKE
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEKWDDLKIFINYGMLTQEDFYEKANKFALLKDTDDKYYTYEEYQSLIKDNQTDKDGNL
HHHHHCCEEEEEECCCCCHHHHHHHHCCEEEEEECCCCEEEHHHHHHHHCCCCCCCCCCE
IYLYATHADEQYSYIDAAKNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDHL
EEEEEECCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IAKEERKDASLEVGQRDILSSVFRSQLPQMKKVEFNVETQSLGETGTPIMITQSEYMRRM
HHHHHCCCCCHHCCHHHHHHHHHHHHCCCCCEEEEECCHHHCCCCCCCEEEECHHHHHHH
KEMANIQAGMSFYGEMPDMFNLVLNVDHKLVKQVLNDADNSCKAALEPIEAEMTSLNKRH
HHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DELHKAQEGKKADEIPQAEKDELSNVEKKLADEKTKKEAVLGEYAGGNKVIRQLIDLALL
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QNNMLKGEALTNFVKRSIELI
HCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLKTLASKGEFKGEMGDLT
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
IKVSLGKDTITISDRGIGLTAEEIDKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYS
EEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHH
AFMVAKKVEIITKSHQEGAQAVKWTCDGSPEFTIENVEKESRGSDIILYIDDDCKEFLEE
HHHHHHHHHHHHHCHHCCCCEEEEEECCCCCEEEECCHHHCCCCEEEEEECHHHHHHHHH
TRISSLLTKYCRFLPIPIAFGKKKEWKDGKQVETNEDNVINETYPLWTRKPVELKDEDYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
KFYRELYPMADEPLFWIHLNVDYPFNLTGILYFPKVKSNIELQKNKIQLYCNQVYVTDSV
HHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCEEECCEEEEEEEEEEEECCC
EGIVPDFLTLLHGVIDSPDIPLNVSRSYLQSDSNVKKISTYISKKVSDRLQAIFKNDRKE
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FEEKWDDLKIFINYGMLTQEDFYEKANKFALLKDTDDKYYTYEEYQSLIKDNQTDKDGNL
HHHHHCCEEEEEECCCCCHHHHHHHHCCEEEEEECCCCEEEHHHHHHHHCCCCCCCCCCE
IYLYATHADEQYSYIDAAKNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDHL
EEEEEECCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IAKEERKDASLEVGQRDILSSVFRSQLPQMKKVEFNVETQSLGETGTPIMITQSEYMRRM
HHHHHCCCCCHHCCHHHHHHHHHHHHCCCCCEEEEECCHHHCCCCCCCEEEECHHHHHHH
KEMANIQAGMSFYGEMPDMFNLVLNVDHKLVKQVLNDADNSCKAALEPIEAEMTSLNKRH
HHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DELHKAQEGKKADEIPQAEKDELSNVEKKLADEKTKKEAVLGEYAGGNKVIRQLIDLALL
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QNNMLKGEALTNFVKRSIELI
HCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11807048 [H]