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The map label for this gene is tesA

Identifier: 148824118

GI number: 148824118

Start: 3253671

End: 3254456

Strand: Direct

Name: tesA

Synonym: TBFG_12943

Alternate gene names: 148824118

Gene position: 3253671-3254456 (Clockwise)

Preceding gene: 148824106

Following gene: 148824119

Centisome position: 73.54

GC content: 54.45

Gene sequence:

>786_bases
ATGCTGGCCCGTCACGGACCACGCTATGGTGGCTCGGTGAACGGGCACTCAGACGACAGTAGCGGCGACGCGAAGCAAGC
CGCACCCACGCTGTATATTTTCCCGCATGCCGGCGGCACCGCGAAAGACTATGTCGCATTTTCCCGAGAATTTTCCGCCG
ACGTAAAGCGGATTGCTGTCCAATACCCCGGCCAGCACGATCGTTCTGGCCTGCCACCGCTTGAGAGTATTCCCACCCTC
GCTGACGAAATCTTTGCAATGATGAAACCGTCGGCTCGGATCGACGATCCGGTGGCATTCTTTGGGCACAGTATGGGCGG
AATGCTAGCCTTCGAAGTAGCGTTGCGATACCAATCGGCGGGCCATCGAGTCCTGGCATTCTTTGTGTCGGCCTGCTCAG
CACCGGGTCATATCAGATACAAGCAGCTCCAAGATTTATCAGATCGCGAGATGTTGGACTTGTTCACCCGAATGACAGGA
ATGAATCCAGATTTCTTTACCGACGACGAATTTTTCGTTGGAGCGCTACCCACGTTGCGAGCGGTCCGAGCCATCGCCGG
TTATTCCTGCCCACCAGAGACGAAGCTCTCGTGTCCGATTTATGCCTTTATCGGAGATAAAGATTGGATCGCAACGCAAG
ACGACATGGATCCGTGGCGCGATCGGACGACGGAAGAGTTCTCTATCCGTGTATTCCCTGGGGATCACTTCTACCTCAAC
GACAATTTGCCAGAGCTAGTCAGCGACATAGAAGACAAAACACTCCAATGGCATGATCGAGCTTAG

Upstream 100 bases:

>100_bases
GCGGCCTGCTGGGCGCGTGTCGTAGACCGTTCGGCGGCTGACGGGTGAGCCTACGTCGTCTGGGCGATCTTGCCCGAGCG
TGCCGACAACGTAGGTGTCG

Downstream 100 bases:

>100_bases
CTATGCTCCGGATGTAGCTGGCCGAAGATCCAACTGGCCGAAGGGCTCGGGGGTCAACACCTGGACAGCCATTCGCTGGA
CATTTGCTGAAGATTCACCG

Product: thioesterase tesA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAVQYPGQHDRSGLPPLESIPTL
ADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDLSDREMLDLFTRMTG
MNPDFFTDDEFFVGALPTLRAVRAIAGYSCPPETKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLN
DNLPELVSDIEDKTLQWHDRA

Sequences:

>Translated_261_residues
MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAVQYPGQHDRSGLPPLESIPTL
ADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDLSDREMLDLFTRMTG
MNPDFFTDDEFFVGALPTLRAVRAIAGYSCPPETKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLN
DNLPELVSDIEDKTLQWHDRA
>Mature_261_residues
MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAVQYPGQHDRSGLPPLESIPTL
ADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDLSDREMLDLFTRMTG
MNPDFFTDDEFFVGALPTLRAVRAIAGYSCPPETKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLN
DNLPELVSDIEDKTLQWHDRA

Specific function: Unknown

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family

Homologues:

Organism=Homo sapiens, GI89257335, Length=225, Percent_Identity=29.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI8922871, Length=208, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TESA_MYCBO (P63461)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856598.1
- ProteinModelPortal:   P63461
- SMR:   P63461
- EnsemblBacteria:   EBMYCT00000015171
- GeneID:   1092153
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2953
- GeneTree:   EBGT00050000015282
- HOGENOM:   HBG756950
- OMA:   GDDDEIA
- ProtClustDB:   CLSK792167
- BioCyc:   MBOV233413:MB2953-MONOMER
- InterPro:   IPR012223
- InterPro:   IPR001031
- PANTHER:   PTHR11487

Pfam domain/function: PF00975 Thioesterase

EC number: NA

Molecular weight: Translated: 29152; Mature: 29152

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAV
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHE
QYPGQHDRSGLPPLESIPTLADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSA
ECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCC
GHRVLAFFVSACSAPGHIRYKQLQDLSDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR
CHHHHHHHHHHHCCCCCEEHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEECCHHHHH
AVRAIAGYSCPPETKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLN
HHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCCEEEEEEECCCEEEEC
DNLPELVSDIEDKTLQWHDRA
CCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAV
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHE
QYPGQHDRSGLPPLESIPTLADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSA
ECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCC
GHRVLAFFVSACSAPGHIRYKQLQDLSDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLR
CHHHHHHHHHHHCCCCCEEHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEECCHHHHH
AVRAIAGYSCPPETKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLN
HHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCCEEEEEEECCCEEEEC
DNLPELVSDIEDKTLQWHDRA
CCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972