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The map label for this gene is 148823290

Identifier: 148823290

GI number: 148823290

Start: 2346028

End: 2347491

Strand: Reverse

Name: 148823290

Synonym: TBFG_12111

Alternate gene names: NA

Gene position: 2347491-2346028 (Counterclockwise)

Preceding gene: 148823291

Following gene: 148823288

Centisome position: 53.06

GC content: 68.31

Gene sequence:

>1464_bases
ATGCCCCGCGCCCGATGGCTGCAGAGCGCGGCCCTCATGGGCGCCTTGGCCGTGGTGTTGATAACCGCGGCACCGGTGGC
CGCCGATGCCTACCAGGTGCCCGCTCCGCCCTCGCCCACCGCATCCTGTGACGTAATAAGCCCGGTTGCGATCCCCTGCG
TGGCGCTCGGCAAGTTCGCCGACGCGGTCGCTGCGGAGTGTCGCCGCGTCGGTGTGCCCGATGCGCGGTGCGTGCTTCCG
CTCGCGCACCGGGTGACCCAGGCCGCGCGTGATGCCTACCTACAGTCTTGGGTGCATCGCACCGCGCGGTTCCAGGATGC
GTTGCAAGACCCGGTGCCGCTGCGGGAAACTCAGTGGCTCGGCACGCACAACTCGTTCAACAGCCTCAGCGATTCGTTCA
CGGTCTCGCACGCAGACTCAAACCAGCAGCTGTCGTTGGCCCAACAGCTCGACATCGACGTCCGCGCGCTCGAGCTAGAC
CTGCACTACTTGCCCCGCCTCGAGGGCCACGGCGCCCCCGGCGTCACCGTGTGTCACGGGCTGGGACCGAAGAACGCGAA
CCTAGGCTGCACCGTCGAACCTCTGCTGGCCACAGTGCTGCCGCAGATCGCCAACTGGTTGAACGCACCCGGGCATACCG
AGGAGGTCATCCTGCTCTACCTGGAGGACCAGCTGAAGAACGCGTCGGCGTATGAGTCGGTGGTGGCTACCCTCGACCAA
GTGTTGCGGCGTGCGGACGGAACAAGCCTTATCTACCGTCCCAACCCGGCCCGGCGTGCCACCAACGGCTGTGTCCCGCT
TCCACTCGACGTGTCGCGGGAGGAAATCCGCGCATCCGGCGCACGAGCCGTGCTCGTCGGGTCTTGTGCGCCAGGTTGGT
CGGCCGCCGTCTTCGACTGGAGCGGCGTTGAGCTGGAAAGCGGCTCGAACTCCGGCTACCGGCCATACCCGGCCTGCGAT
GCCACCTATGGCCGCGGTGTCTACGCTTGGCGACTGGTCCGCTATTACGAGGACTCCACGCTGGCCACGGCGTTGGCCAA
CCCGACCCGTCCACCGGCCAATCCGCAGGCGCTTACCCCGCCGAAGGTGCCGGCGATGACCGATTGCGGGGTCAATCTGT
TCGGCTTCGATCAGCTGCTCCCCGAAGACGGCCGCATTCAGGCGTCGTTGTGGAGCTGGGCACCGGACGAACCGCGTGCC
GGTGCCGGAGCATGCGCCCTGCAGGGCGCGGATGGCCGCTGGGTCGCCGCATCGTGCGGTGACCCACACCCTGCGGCCTG
TCGGGACGCGGCAGGCAGGTGGACCGTGACGCCGGCACCCGTGGTCTTCGCCGGGGCTGCCCTAGCCTGCACAGCCATCG
GCGCGGACTTTACCCTGCCCCGAACGGGCAATCAGAACGCCCGTCTGCACGCCGTGGCCGGGCCCGCCGGTGGCGCCTGG
GTGCATTACCTACTGCCGCCATGA

Upstream 100 bases:

>100_bases
GACGCGGGGCGGCTTGGAGTTACGTGACGGCTTCGACGAGACCACGCAACACTTCGACAACACCCCTGGTAAGCGGTGTA
TCGACGTGCCAAAGTAGCGC

Downstream 100 bases:

>100_bases
CCTCGGTTGTCAGGCCCGGTCGAGCAGATCCGCGGATCCCAGCACGCGCTCAATCTGGACCTCGATGACCACTCGGCGTG
GATTGGGACGCGGGGTGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MPRARWLQSAALMGALAVVLITAAPVAADAYQVPAPPSPTASCDVISPVAIPCVALGKFADAVAAECRRVGVPDARCVLP
LAHRVTQAARDAYLQSWVHRTARFQDALQDPVPLRETQWLGTHNSFNSLSDSFTVSHADSNQQLSLAQQLDIDVRALELD
LHYLPRLEGHGAPGVTVCHGLGPKNANLGCTVEPLLATVLPQIANWLNAPGHTEEVILLYLEDQLKNASAYESVVATLDQ
VLRRADGTSLIYRPNPARRATNGCVPLPLDVSREEIRASGARAVLVGSCAPGWSAAVFDWSGVELESGSNSGYRPYPACD
ATYGRGVYAWRLVRYYEDSTLATALANPTRPPANPQALTPPKVPAMTDCGVNLFGFDQLLPEDGRIQASLWSWAPDEPRA
GAGACALQGADGRWVAASCGDPHPAACRDAAGRWTVTPAPVVFAGAALACTAIGADFTLPRTGNQNARLHAVAGPAGGAW
VHYLLPP

Sequences:

>Translated_487_residues
MPRARWLQSAALMGALAVVLITAAPVAADAYQVPAPPSPTASCDVISPVAIPCVALGKFADAVAAECRRVGVPDARCVLP
LAHRVTQAARDAYLQSWVHRTARFQDALQDPVPLRETQWLGTHNSFNSLSDSFTVSHADSNQQLSLAQQLDIDVRALELD
LHYLPRLEGHGAPGVTVCHGLGPKNANLGCTVEPLLATVLPQIANWLNAPGHTEEVILLYLEDQLKNASAYESVVATLDQ
VLRRADGTSLIYRPNPARRATNGCVPLPLDVSREEIRASGARAVLVGSCAPGWSAAVFDWSGVELESGSNSGYRPYPACD
ATYGRGVYAWRLVRYYEDSTLATALANPTRPPANPQALTPPKVPAMTDCGVNLFGFDQLLPEDGRIQASLWSWAPDEPRA
GAGACALQGADGRWVAASCGDPHPAACRDAAGRWTVTPAPVVFAGAALACTAIGADFTLPRTGNQNARLHAVAGPAGGAW
VHYLLPP
>Mature_486_residues
PRARWLQSAALMGALAVVLITAAPVAADAYQVPAPPSPTASCDVISPVAIPCVALGKFADAVAAECRRVGVPDARCVLPL
AHRVTQAARDAYLQSWVHRTARFQDALQDPVPLRETQWLGTHNSFNSLSDSFTVSHADSNQQLSLAQQLDIDVRALELDL
HYLPRLEGHGAPGVTVCHGLGPKNANLGCTVEPLLATVLPQIANWLNAPGHTEEVILLYLEDQLKNASAYESVVATLDQV
LRRADGTSLIYRPNPARRATNGCVPLPLDVSREEIRASGARAVLVGSCAPGWSAAVFDWSGVELESGSNSGYRPYPACDA
TYGRGVYAWRLVRYYEDSTLATALANPTRPPANPQALTPPKVPAMTDCGVNLFGFDQLLPEDGRIQASLWSWAPDEPRAG
AGACALQGADGRWVAASCGDPHPAACRDAAGRWTVTPAPVVFAGAALACTAIGADFTLPRTGNQNARLHAVAGPAGGAWV
HYLLPP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2075_MYCTU (Q10683)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   F70765
- RefSeq:   NP_216591.1
- RefSeq:   NP_336601.1
- ProteinModelPortal:   Q10683
- EnsemblBacteria:   EBMYCT00000003698
- EnsemblBacteria:   EBMYCT00000069200
- GeneID:   888771
- GeneID:   924594
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2135
- KEGG:   mtu:Rv2075c
- TIGR:   MT2135
- TubercuList:   Rv2075c
- GeneTree:   EBGT00050000018474
- HOGENOM:   HBG569357
- OMA:   SYNSSAY
- ProtClustDB:   CLSK791608
- InterPro:   IPR017946
- InterPro:   IPR000909
- Gene3D:   G3DSA:3.20.20.190

Pfam domain/function: SSF51695 PLC-like_Pdiesterase_TIM-brl

EC number: NA

Molecular weight: Translated: 51581; Mature: 51450

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50007 PIPLC_X_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b229a04)-; HASH(0x1b730f64)-; HASH(0x1b7d3e58)-;

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRARWLQSAALMGALAVVLITAAPVAADAYQVPAPPSPTASCDVISPVAIPCVALGKFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
DAVAAECRRVGVPDARCVLPLAHRVTQAARDAYLQSWVHRTARFQDALQDPVPLRETQWL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
GTHNSFNSLSDSFTVSHADSNQQLSLAQQLDIDVRALELDLHYLPRLEGHGAPGVTVCHG
CCCCCHHHCCCCEEEEECCCCCHHHHHHHCCCEEEEEEEEHHHCCCCCCCCCCCEEEEEC
LGPKNANLGCTVEPLLATVLPQIANWLNAPGHTEEVILLYLEDQLKNASAYESVVATLDQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
VLRRADGTSLIYRPNPARRATNGCVPLPLDVSREEIRASGARAVLVGSCAPGWSAAVFDW
HHHHCCCCEEEECCCCHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCEEEEEC
SGVELESGSNSGYRPYPACDATYGRGVYAWRLVRYYEDSTLATALANPTRPPANPQALTP
CCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCC
PKVPAMTDCGVNLFGFDQLLPEDGRIQASLWSWAPDEPRAGAGACALQGADGRWVAASCG
CCCCCHHCCCCCEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCEEEECCC
DPHPAACRDAAGRWTVTPAPVVFAGAALACTAIGADFTLPRTGNQNARLHAVAGPAGGAW
CCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEECCCCCCE
VHYLLPP
EEEECCH
>Mature Secondary Structure 
PRARWLQSAALMGALAVVLITAAPVAADAYQVPAPPSPTASCDVISPVAIPCVALGKFA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
DAVAAECRRVGVPDARCVLPLAHRVTQAARDAYLQSWVHRTARFQDALQDPVPLRETQWL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
GTHNSFNSLSDSFTVSHADSNQQLSLAQQLDIDVRALELDLHYLPRLEGHGAPGVTVCHG
CCCCCHHHCCCCEEEEECCCCCHHHHHHHCCCEEEEEEEEHHHCCCCCCCCCCCEEEEEC
LGPKNANLGCTVEPLLATVLPQIANWLNAPGHTEEVILLYLEDQLKNASAYESVVATLDQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
VLRRADGTSLIYRPNPARRATNGCVPLPLDVSREEIRASGARAVLVGSCAPGWSAAVFDW
HHHHCCCCEEEECCCCHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCEEEEEC
SGVELESGSNSGYRPYPACDATYGRGVYAWRLVRYYEDSTLATALANPTRPPANPQALTP
CCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCC
PKVPAMTDCGVNLFGFDQLLPEDGRIQASLWSWAPDEPRAGAGACALQGADGRWVAASCG
CCCCCHHCCCCCEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCEEEECCC
DPHPAACRDAAGRWTVTPAPVVFAGAALACTAIGADFTLPRTGNQNARLHAVAGPAGGAW
CCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEECCCCCCE
VHYLLPP
EEEECCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036