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The map label for this gene is fadE5 [C]

Identifier: 148660009

GI number: 148660009

Start: 295160

End: 296995

Strand: Reverse

Name: fadE5 [C]

Synonym: MRA_0253

Alternate gene names: 148660009

Gene position: 296995-295160 (Counterclockwise)

Preceding gene: 148660012

Following gene: 148660007

Centisome position: 6.72

GC content: 64.27

Gene sequence:

>1836_bases
GTGAGCCACTACCGGAGCAACGTCCGTGACCAGGTTTTTAACCTGTTCGAAGTGCTGGGCGTCGACAAAGCTTTGGGCCA
TGGCGAATTCAGCGACGTCGACGTCGACACCGCCCGCGACATGCTGGCCGAGGTCAGCCGGCTGGCCGAGGGGCCGGTGG
CCGAGTCGTTCGTCGAAGGGGACCGCAACCCGCCCGTTTTCGACCCGAAAACCCACTCGGTGATGCTGCCGGAATCGTTC
AAAAAGTCAGTCAACGCGATGCTGGAAGCCGGTTGGGACAAGGTCGGCATCGACGAGGCACTCGGGGGCATGCCGATGCC
CAAGGCAGTGGTCTGGGCGCTGCATGAGCACATCTTGGGCGCCAATCCGGCGGTATGGATGTACGCCGGCGGCGCGGGCT
TCGCCCAGATCCTCTACCACCTCGGCACCGAGGAGCAGAAGAAGTGGGCGGTCCTAGCCGCCGAACGCGGCTGGGGATCG
ACCATGGTGCTCACCGAGCCGGATGCCGGCTCCGATGTGGGCGCTGCCCGAACCAAAGCTGTCCAACAGGCCGACGGGTC
CTGGCACATCGACGGCGTCAAGCGGTTCATTACCTCGGGTGACTCCGGCGACCTGTTCGAGAACATCTTCCACCTGGTGC
TGGCTCGCCCGGAGGGCGCCGGTCCCGGCACCAAGGGCCTGTCGCTGTACTTCGTGCCCAAGTTCCTGTTCGACGTCGAA
ACCGGCGAACCCGGCGAGCGCAATGGCGTGTTCGTCACCAACGTCGAACACAAGATGGGCCTAAAGGTCTCGGCGACCTG
TGAACTGGCGTTCGGCCAACACGGCGTCCCCGCCAAGGGCTGGCTGGTCGGCGAGGTACACAACGGCATCGCGCAGATGT
TCGAGGTCATTGAGCAGGCCCGCATGATGGTCGGCACGAAGGCCATCGCGACGCTGTCCACCGGCTACCTCAACGCGCTT
CAGTACGCCAAGTCCCGCGTGCAGGGTGCCGACCTGACCCAGATGACCGACAAGACCGCGCCCCGGGTGACGATCACACA
TCACCCCGACGTGCGCCGCTCGCTGATGACCCAGAAGGCTTACGCCGAGGGCCTGCGTGCGCTCTACCTCTACACCGCCA
CTTTCCAGGACGCGGCTGTCGCCGAGGTGGTGCACGGTGTGGACGCCAAGTTGGCCGTCAAGGTCAACGACCTGATGTTG
CCGGTAGTCAAGGGTGTGGGCTCCGAACAGGCTTACGCCAAGCTCACTGAAAGCCTGCAAACCCTGGGTGGATCCGGCTT
CTTGCAGGACTATCCGATCGAGCAGTACATCCGGGACGCCAAGATCGACTCCCTGTACGAAGGCACCACCGCCATCCAGG
CACAAGACTTCTTCTTCCGCAAAATCGTCCGTGACAAGGGCGTGGCGTTGGCGCACGTGTCAGGCCAGATCCAGGAGTTC
GTCGACAGCGGTGCTGGCAACGGCCGGCTGAAGACCGAACGCGCGCTGCTGGCCAAGGCGCTCACCGACGTCCAGGGCAT
GGCGGCCGCACTGACCGGCTACCTGATGGCCGCGCAGCAGGACGTCACCAGCCTCTACAAGGTGGGCTTGGGTTCGGTGC
GCTTCTTGATGAGCGTCGGTGACCTCATCATCGGCTGGTTGCTGCAGCGTCAGGCCGCGGTGGCGGTGGCGGCACTCGAC
GCGGGTGCCACCGGCGACGAGCGGTCCTTCTACGAAGGCAAAGTCGCGGTGGCGTCGTTCTTCGCGAAGAACTTCTTGCC
GCTGTTGACCAGCACCCGCGAGGTGATCGAGACGCTGGACAACGACATCATGGAACTCGACGAGGCCGCGTTCTGA

Upstream 100 bases:

>100_bases
CAACGGATATATTTTGACGGTGTTACTGGTGGGTAACTTGGTTTCGAGTACCCAACCCTACCCAACCCTGAGGTGGCACT
CTCAACGAGGAGGATCGGCA

Downstream 100 bases:

>100_bases
TCCTTATCTGTTGACTCTGCGTCCACCGGACGGGTTACTCGCACTTTTGCGTGGTGGACGCAGAGTCAACGAACGATGGG
GCAAGCCCAAAAAGACCGCC

Product: acyl-CoA dehydrogenase FadE5

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MSHYRSNVRDQVFNLFEVLGVDKALGHGEFSDVDVDTARDMLAEVSRLAEGPVAESFVEGDRNPPVFDPKTHSVMLPESF
KKSVNAMLEAGWDKVGIDEALGGMPMPKAVVWALHEHILGANPAVWMYAGGAGFAQILYHLGTEEQKKWAVLAAERGWGS
TMVLTEPDAGSDVGAARTKAVQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPEGAGPGTKGLSLYFVPKFLFDVE
TGEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGVPAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL
QYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDAAVAEVVHGVDAKLAVKVNDLML
PVVKGVGSEQAYAKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSGQIQEF
VDSGAGNGRLKTERALLAKALTDVQGMAAALTGYLMAAQQDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVAALD
AGATGDERSFYEGKVAVASFFAKNFLPLLTSTREVIETLDNDIMELDEAAF

Sequences:

>Translated_611_residues
MSHYRSNVRDQVFNLFEVLGVDKALGHGEFSDVDVDTARDMLAEVSRLAEGPVAESFVEGDRNPPVFDPKTHSVMLPESF
KKSVNAMLEAGWDKVGIDEALGGMPMPKAVVWALHEHILGANPAVWMYAGGAGFAQILYHLGTEEQKKWAVLAAERGWGS
TMVLTEPDAGSDVGAARTKAVQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPEGAGPGTKGLSLYFVPKFLFDVE
TGEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGVPAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL
QYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDAAVAEVVHGVDAKLAVKVNDLML
PVVKGVGSEQAYAKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSGQIQEF
VDSGAGNGRLKTERALLAKALTDVQGMAAALTGYLMAAQQDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVAALD
AGATGDERSFYEGKVAVASFFAKNFLPLLTSTREVIETLDNDIMELDEAAF
>Mature_610_residues
SHYRSNVRDQVFNLFEVLGVDKALGHGEFSDVDVDTARDMLAEVSRLAEGPVAESFVEGDRNPPVFDPKTHSVMLPESFK
KSVNAMLEAGWDKVGIDEALGGMPMPKAVVWALHEHILGANPAVWMYAGGAGFAQILYHLGTEEQKKWAVLAAERGWGST
MVLTEPDAGSDVGAARTKAVQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPEGAGPGTKGLSLYFVPKFLFDVET
GEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGVPAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNALQ
YAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDAAVAEVVHGVDAKLAVKVNDLMLP
VVKGVGSEQAYAKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSGQIQEFV
DSGAGNGRLKTERALLAKALTDVQGMAAALTGYLMAAQQDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVAALDA
GATGDERSFYEGKVAVASFFAKNFLPLLTSTREVIETLDNDIMELDEAAF

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=316, Percent_Identity=27.5316455696203, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557233, Length=318, Percent_Identity=27.9874213836478, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI4501857, Length=391, Percent_Identity=26.8542199488491, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI187960098, Length=310, Percent_Identity=28.0645161290323, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI4557231, Length=310, Percent_Identity=28.0645161290323, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI4557235, Length=324, Percent_Identity=25, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI76496475, Length=326, Percent_Identity=25.1533742331288, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI87082384, Length=333, Percent_Identity=28.2282282282282, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786223, Length=403, Percent_Identity=26.5508684863524, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=23.9473684210526, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=317, Percent_Identity=30.2839116719243, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=318, Percent_Identity=28.9308176100629, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=312, Percent_Identity=23.7179487179487, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=393, Percent_Identity=25.6997455470738, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=393, Percent_Identity=25.6997455470738, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=294, Percent_Identity=26.8707482993197, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=25.9358288770053, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24660351, Length=327, Percent_Identity=28.1345565749235, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363737, Length=327, Percent_Identity=25.3822629969419, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356377, Length=394, Percent_Identity=27.6649746192893, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646207, Length=322, Percent_Identity=25.1552795031056, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 66047; Mature: 65916

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHYRSNVRDQVFNLFEVLGVDKALGHGEFSDVDVDTARDMLAEVSRLAEGPVAESFVEG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCC
DRNPPVFDPKTHSVMLPESFKKSVNAMLEAGWDKVGIDEALGGMPMPKAVVWALHEHILG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHC
ANPAVWMYAGGAGFAQILYHLGTEEQKKWAVLAAERGWGSTMVLTEPDAGSDVGAARTKA
CCCCEEEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHH
VQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPEGAGPGTKGLSLYFVPKFLFDVE
HHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHEECC
TGEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGVPAKGWLVGEVHNGIAQMFEVIEQA
CCCCCCCCCEEEEECHHHHCCEEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
RMMVGTKAIATLSTGYLNALQYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHH
YAEGLRALYLYTATFQDAAVAEVVHGVDAKLAVKVNDLMLPVVKGVGSEQAYAKLTESLQ
HHHHHHEEEEEEECCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHH
TLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSGQIQEF
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHCCCEEEEHHHHHHHH
VDSGAGNGRLKTERALLAKALTDVQGMAAALTGYLMAAQQDVTSLYKVGLGSVRFLMSVG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DLIIGWLLQRQAAVAVAALDAGATGDERSFYEGKVAVASFFAKNFLPLLTSTREVIETLD
HHHHHHHHHHHHHHHHEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDIMELDEAAF
HHHHHHHHCCC
>Mature Secondary Structure 
SHYRSNVRDQVFNLFEVLGVDKALGHGEFSDVDVDTARDMLAEVSRLAEGPVAESFVEG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCC
DRNPPVFDPKTHSVMLPESFKKSVNAMLEAGWDKVGIDEALGGMPMPKAVVWALHEHILG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHC
ANPAVWMYAGGAGFAQILYHLGTEEQKKWAVLAAERGWGSTMVLTEPDAGSDVGAARTKA
CCCCEEEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHH
VQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPEGAGPGTKGLSLYFVPKFLFDVE
HHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHEECC
TGEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGVPAKGWLVGEVHNGIAQMFEVIEQA
CCCCCCCCCEEEEECHHHHCCEEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
RMMVGTKAIATLSTGYLNALQYAKSRVQGADLTQMTDKTAPRVTITHHPDVRRSLMTQKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHH
YAEGLRALYLYTATFQDAAVAEVVHGVDAKLAVKVNDLMLPVVKGVGSEQAYAKLTESLQ
HHHHHHEEEEEEECCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHH
TLGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSGQIQEF
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHCCCEEEEHHHHHHHH
VDSGAGNGRLKTERALLAKALTDVQGMAAALTGYLMAAQQDVTSLYKVGLGSVRFLMSVG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DLIIGWLLQRQAAVAVAALDAGATGDERSFYEGKVAVASFFAKNFLPLLTSTREVIETLD
HHHHHHHHHHHHHHHHEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDIMELDEAAF
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]