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The map label for this gene is galE [H]

Identifier: 148652043

GI number: 148652043

Start: 267648

End: 268703

Strand: Direct

Name: galE [H]

Synonym: PsycPRwf_0227

Alternate gene names: 148652043

Gene position: 267648-268703 (Clockwise)

Preceding gene: 148652042

Following gene: 148652070

Centisome position: 8.98

GC content: 45.08

Gene sequence:

>1056_bases
ATGATGAGTAATAAAATTTTAGTAACTGGTGGTGTGGGTTATATCGGCTCACACACTTGTATTGAGCTAATAGCAGCAGG
CTACGAGGTTGTGGTCTATGACAACTTGTCTAACAGTAACCTTGAAGCGTTAAAACGCACTGAGCAAATTGCCGGTAAAG
AGATTGCCTTTATCGAAGGGGATGTACTAGATAGCAAGCTATTGAATCAAGTATTCGATGAACATGACTTCTTCGGAGTA
ATTCACTTTGCTGGACTTAAAGCTGTGGGAGAGTCGGTTGCTCAGCCATTAAGATATTATAAAAATAATGTCACGGGCAC
TCTTGTGCTGCTAGAGGTAATGCAAGCGCATAATGTGAAAAACTTTGTTTTCTCATCTTCTGCTACTGTTTATGGCGATC
CTGAGACACTACCTATCCCGGAAACAGCCCCTCGCTCTTGTACCAATCCTTATGGTCAATCTAAGTTAACCGTTGAGCAT
ATCTTGCAGGATTTGGCGCAGGCTGATCCGAGCTGGAGTATTACTTGTCTACGCTACTTTAATCCAGTAGGTGCGCATAG
CTCTGGCTCAATTGGAGAGGATCCCAATGGCATCCCTAACAACTTAATGCCGTATATCAGCCAAGTAGCCGTCGGTAAGC
TTAAGCAGCTGAGTGTCTTTGGCAGTGATTATTATACAGTCGATGGTACTGGGGTGCGTGACTTTATCCATGTGGTGGAT
TTAGCAAAAGGCCATGTGGCTGCCTTAGATTATATTACTTACAATCAAAGCCAACAAAGTCAGCAAGCATCCAAAGCTGG
CCTAGGCTTTGAGGCGATTAACTTAGGCACCGGTAATGGTAGCTCGGTGCTGCAACTGGTAGAAGCTTTTGAAAAAGTGA
CCGGTCAAAAGGTGCCTTATCAATTGGTAGACAGGCGCCCTGGAGACATTGCGGCTTGTTACGCCAGTGCTGATAAAGCC
AAACACTTGCTAGGCTGGCAGGCTGAGCTAACGATTGAAGATATGTGTAAGGACAGCTGGCGTTGGCAGAGTCAGAATCC
AGGTGGGTATAAGTAG

Upstream 100 bases:

>100_bases
GCTTTAGTGGGGTGACTATTAGCCGGTTAGATAAGCAGGCTTAAGCGAGTACAATTAAACTATTAATTTAAACATTTAAA
ATAAAAACCAATCTGGATTG

Downstream 100 bases:

>100_bases
ACAAGTTAGCGATAGCAATGAAAATAGCCCCTAGATTAATGAATCTAAGGGCTGTTTTTATTTGTATAACCTAGAATGAA
AACTTAAAAATTCGCAAACT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MMSNKILVTGGVGYIGSHTCIELIAAGYEVVVYDNLSNSNLEALKRTEQIAGKEIAFIEGDVLDSKLLNQVFDEHDFFGV
IHFAGLKAVGESVAQPLRYYKNNVTGTLVLLEVMQAHNVKNFVFSSSATVYGDPETLPIPETAPRSCTNPYGQSKLTVEH
ILQDLAQADPSWSITCLRYFNPVGAHSSGSIGEDPNGIPNNLMPYISQVAVGKLKQLSVFGSDYYTVDGTGVRDFIHVVD
LAKGHVAALDYITYNQSQQSQQASKAGLGFEAINLGTGNGSSVLQLVEAFEKVTGQKVPYQLVDRRPGDIAACYASADKA
KHLLGWQAELTIEDMCKDSWRWQSQNPGGYK

Sequences:

>Translated_351_residues
MMSNKILVTGGVGYIGSHTCIELIAAGYEVVVYDNLSNSNLEALKRTEQIAGKEIAFIEGDVLDSKLLNQVFDEHDFFGV
IHFAGLKAVGESVAQPLRYYKNNVTGTLVLLEVMQAHNVKNFVFSSSATVYGDPETLPIPETAPRSCTNPYGQSKLTVEH
ILQDLAQADPSWSITCLRYFNPVGAHSSGSIGEDPNGIPNNLMPYISQVAVGKLKQLSVFGSDYYTVDGTGVRDFIHVVD
LAKGHVAALDYITYNQSQQSQQASKAGLGFEAINLGTGNGSSVLQLVEAFEKVTGQKVPYQLVDRRPGDIAACYASADKA
KHLLGWQAELTIEDMCKDSWRWQSQNPGGYK
>Mature_351_residues
MMSNKILVTGGVGYIGSHTCIELIAAGYEVVVYDNLSNSNLEALKRTEQIAGKEIAFIEGDVLDSKLLNQVFDEHDFFGV
IHFAGLKAVGESVAQPLRYYKNNVTGTLVLLEVMQAHNVKNFVFSSSATVYGDPETLPIPETAPRSCTNPYGQSKLTVEH
ILQDLAQADPSWSITCLRYFNPVGAHSSGSIGEDPNGIPNNLMPYISQVAVGKLKQLSVFGSDYYTVDGTGVRDFIHVVD
LAKGHVAALDYITYNQSQQSQQASKAGLGFEAINLGTGNGSSVLQLVEAFEKVTGQKVPYQLVDRRPGDIAACYASADKA
KHLLGWQAELTIEDMCKDSWRWQSQNPGGYK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=356, Percent_Identity=56.7415730337079, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI56118217, Length=356, Percent_Identity=56.7415730337079, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI189083684, Length=356, Percent_Identity=56.7415730337079, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI7657641, Length=363, Percent_Identity=25.6198347107438, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI42516563, Length=340, Percent_Identity=25.2941176470588, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786974, Length=347, Percent_Identity=53.6023054755043, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI48994969, Length=373, Percent_Identity=27.0777479892761, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788353, Length=372, Percent_Identity=26.0752688172043, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=353, Percent_Identity=52.6912181303116, Blast_Score=379, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71982038, Length=355, Percent_Identity=52.3943661971831, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17539532, Length=257, Percent_Identity=26.4591439688716, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=355, Percent_Identity=54.9295774647887, Blast_Score=388, Evalue=1e-109,
Organism=Drosophila melanogaster, GI19923002, Length=357, Percent_Identity=56.8627450980392, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI21356223, Length=347, Percent_Identity=24.4956772334294, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38206; Mature: 38206

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSNKILVTGGVGYIGSHTCIELIAAGYEVVVYDNLSNSNLEALKRTEQIAGKEIAFIEG
CCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEC
DVLDSKLLNQVFDEHDFFGVIHFAGLKAVGESVAQPLRYYKNNVTGTLVLLEVMQAHNVK
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHH
NFVFSSSATVYGDPETLPIPETAPRSCTNPYGQSKLTVEHILQDLAQADPSWSITCLRYF
HHEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEEEC
NPVGAHSSGSIGEDPNGIPNNLMPYISQVAVGKLKQLSVFGSDYYTVDGTGVRDFIHVVD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCEEEECCCCHHHHHHHHH
LAKGHVAALDYITYNQSQQSQQASKAGLGFEAINLGTGNGSSVLQLVEAFEKVTGQKVPY
HCCCCEEEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCH
QLVDRRPGDIAACYASADKAKHLLGWQAELTIEDMCKDSWRWQSQNPGGYK
HHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMSNKILVTGGVGYIGSHTCIELIAAGYEVVVYDNLSNSNLEALKRTEQIAGKEIAFIEG
CCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEC
DVLDSKLLNQVFDEHDFFGVIHFAGLKAVGESVAQPLRYYKNNVTGTLVLLEVMQAHNVK
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHH
NFVFSSSATVYGDPETLPIPETAPRSCTNPYGQSKLTVEHILQDLAQADPSWSITCLRYF
HHEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEEEC
NPVGAHSSGSIGEDPNGIPNNLMPYISQVAVGKLKQLSVFGSDYYTVDGTGVRDFIHVVD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCEEEECCCCHHHHHHHHH
LAKGHVAALDYITYNQSQQSQQASKAGLGFEAINLGTGNGSSVLQLVEAFEKVTGQKVPY
HCCCCEEEEEEEECCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCH
QLVDRRPGDIAACYASADKAKHLLGWQAELTIEDMCKDSWRWQSQNPGGYK
HHHCCCCCCEEEEHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]