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The map label for this gene is nhaC [H]

Identifier: 148652042

GI number: 148652042

Start: 266107

End: 267591

Strand: Direct

Name: nhaC [H]

Synonym: PsycPRwf_0226

Alternate gene names: 148652042

Gene position: 266107-267591 (Clockwise)

Preceding gene: 148652038

Following gene: 148652043

Centisome position: 8.93

GC content: 47.74

Gene sequence:

>1485_bases
ATGTCATCAAATACCCCCGCTCAGCCTGATCACACCGACTCTACTCACCACGCCCAGTCAACGCCTAACCCTGCTTTCAC
TCAGCTATCAAGCCATTCGCCGCAGCCCGAGCCACAGCTGTCGCCCATCCAAGCCTTTGTGATGGCCGGATGTGTTGTTT
TAATTATGGGCGTGACCATGATTGGCTTTGGCTGGGTGCCGCACTTGTCATTGCTATTAGCGATTTGCTTTTTGTTATTG
ATGGGGCGGCTAAGAGGATTGAGCTTTACCCATCTACAGTCGGCGATGACAGATGGGGTGGTCAGTGGCAGCGGGGCTAT
CTATCTGTTTTTCTTTATCGGGCTTATGGTGGCAGCTTTAATGATGTCGGGGGCCATTCCCACCTTGATGTACTTCGGCT
TTGAGCTGATTTCTCCACGGTTTTATTATATTTCAGCCTTTGTGCTCACCTCTATTATTGGTATTGCCTTAGGCAGCAGC
TTGACCACGGTAGCGACGCTTGGCGTGGCCTTTATTGGCATGAGTAATGCCTTTGATGCCAATGTGGCCATTGCGGCAGG
TGCAGTGGTCTCTGGGGCCTTCTTCGGTGATAAGATGTCGCCGCTGTCTGATACCGGTACCATTGCGTCGTCTGTGGTGG
GTATTGATCTGTTTGAGCACTTACGCAATATGATGTATACCACGGTGCCGGCTTGGATCATTAGCGTTCTGTTGTTTTGG
ATGTTAACGGGGCCGATGCAAATCGCCAATTTAGGCCAAGTCACTGTACTACAAAATCAGCTTGTCGCAAGTGGCTTGGT
ACATAGCTATGCTGTATTGCCGTTTGTGGTATTAATAGTGTTGGCCATGTTTCGAGTCAATGCCATCTATACCATTATTT
GCACCATTATCAGTGCCTTGATGATTACTTATATACATAGCTCACCCAGTATTGAGCAATTGGGTGGTTATCTGTTTGCT
GGATATGCGCCGGCTTCAAATTTAGAGTTAGGAGAAGTAGGGAGCATGCTGACCCGTGGTGGTATCCAAAGTATGTTCTT
TACGCAGACCATTGTGATCTTGGCGTTAAGTCTGGGCGGATTGTTAAAAAAACTGGGTATTTTGCCGGCCTTGCTGGCTG
GCGTGCGTGATAAATTGACCACAGCCGGCCAGGCCATCTTTGCAGCGGCTATGTCAGCTCTTAGCATCAATGTGCTTATT
GGCGAGCAGTATCTAAGTATCTTGTTATCAGGAACGGCATTTCGCCCGACTTTTGAACGTTTGAGCTTACATCCTAAGAA
CTTATCACGTACTATTGAAGATGCTGGTACGGTGATTAATCCCTTGGTGCCTTGGAGTGTGTGTGGGGTGTTTATTAGCC
AAGCGCTTGAGGTGCCGGTATTAGAGTATCTGCCTTATGCGTTCTTTTGTTATTTATCGTTGCTGCTGACTATTTTATTT
GGCTTTAGTGGGGTGACTATTAGCCGGTTAGATAAGCAGGCTTAA

Upstream 100 bases:

>100_bases
AATTGTTTGCATGCTTATTGCGCCAAAGCTTATGTAATTGCTCAAAAAATTGCTATTATGGGCGCTTTTTATGCCGCGTC
GCTTATCAAACGGATAGTGT

Downstream 100 bases:

>100_bases
GCGAGTACAATTAAACTATTAATTTAAACATTTAAAATAAAAACCAATCTGGATTGATGATGAGTAATAAAATTTTAGTA
ACTGGTGGTGTGGGTTATAT

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSSNTPAQPDHTDSTHHAQSTPNPAFTQLSSHSPQPEPQLSPIQAFVMAGCVVLIMGVTMIGFGWVPHLSLLLAICFLLL
MGRLRGLSFTHLQSAMTDGVVSGSGAIYLFFFIGLMVAALMMSGAIPTLMYFGFELISPRFYYISAFVLTSIIGIALGSS
LTTVATLGVAFIGMSNAFDANVAIAAGAVVSGAFFGDKMSPLSDTGTIASSVVGIDLFEHLRNMMYTTVPAWIISVLLFW
MLTGPMQIANLGQVTVLQNQLVASGLVHSYAVLPFVVLIVLAMFRVNAIYTIICTIISALMITYIHSSPSIEQLGGYLFA
GYAPASNLELGEVGSMLTRGGIQSMFFTQTIVILALSLGGLLKKLGILPALLAGVRDKLTTAGQAIFAAAMSALSINVLI
GEQYLSILLSGTAFRPTFERLSLHPKNLSRTIEDAGTVINPLVPWSVCGVFISQALEVPVLEYLPYAFFCYLSLLLTILF
GFSGVTISRLDKQA

Sequences:

>Translated_494_residues
MSSNTPAQPDHTDSTHHAQSTPNPAFTQLSSHSPQPEPQLSPIQAFVMAGCVVLIMGVTMIGFGWVPHLSLLLAICFLLL
MGRLRGLSFTHLQSAMTDGVVSGSGAIYLFFFIGLMVAALMMSGAIPTLMYFGFELISPRFYYISAFVLTSIIGIALGSS
LTTVATLGVAFIGMSNAFDANVAIAAGAVVSGAFFGDKMSPLSDTGTIASSVVGIDLFEHLRNMMYTTVPAWIISVLLFW
MLTGPMQIANLGQVTVLQNQLVASGLVHSYAVLPFVVLIVLAMFRVNAIYTIICTIISALMITYIHSSPSIEQLGGYLFA
GYAPASNLELGEVGSMLTRGGIQSMFFTQTIVILALSLGGLLKKLGILPALLAGVRDKLTTAGQAIFAAAMSALSINVLI
GEQYLSILLSGTAFRPTFERLSLHPKNLSRTIEDAGTVINPLVPWSVCGVFISQALEVPVLEYLPYAFFCYLSLLLTILF
GFSGVTISRLDKQA
>Mature_493_residues
SSNTPAQPDHTDSTHHAQSTPNPAFTQLSSHSPQPEPQLSPIQAFVMAGCVVLIMGVTMIGFGWVPHLSLLLAICFLLLM
GRLRGLSFTHLQSAMTDGVVSGSGAIYLFFFIGLMVAALMMSGAIPTLMYFGFELISPRFYYISAFVLTSIIGIALGSSL
TTVATLGVAFIGMSNAFDANVAIAAGAVVSGAFFGDKMSPLSDTGTIASSVVGIDLFEHLRNMMYTTVPAWIISVLLFWM
LTGPMQIANLGQVTVLQNQLVASGLVHSYAVLPFVVLIVLAMFRVNAIYTIICTIISALMITYIHSSPSIEQLGGYLFAG
YAPASNLELGEVGSMLTRGGIQSMFFTQTIVILALSLGGLLKKLGILPALLAGVRDKLTTAGQAIFAAAMSALSINVLIG
EQYLSILLSGTAFRPTFERLSLHPKNLSRTIEDAGTVINPLVPWSVCGVFISQALEVPVLEYLPYAFFCYLSLLLTILFG
FSGVTISRLDKQA

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 52698; Mature: 52567

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHCCCC
>Mature Secondary Structure 
SSNTPAQPDHTDSTHHAQSTPNPAFTQLSSHSPQPEPQLSPIQAFVMAGCVVLIMGVTM
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH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CCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]