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The map label for this gene is moaE [C]

Identifier: 148652038

GI number: 148652038

Start: 261973

End: 262488

Strand: Direct

Name: moaE [C]

Synonym: PsycPRwf_0222

Alternate gene names: 148652038

Gene position: 261973-262488 (Clockwise)

Preceding gene: 148652037

Following gene: 148652042

Centisome position: 8.79

GC content: 47.29

Gene sequence:

>516_bases
ATGGACAGTCAATCTGCTTTGGACACGGCCAATCAGCCGCATCAGCAGGCAAGTAGCATATCGCACAGCGTAGATGAGGT
ATATCAGCTGGCACAGTCTCAAGGCTTTGCGCTGCTTGATGAAGCCATTGACGCTGAGCGCCTAAAAGATATGCTGCAAG
ATGATCAGTGCGGCGCTTTGGCCACCTTTGAGGGCTGGGTACGCAATCACAATAACGACAGCCAAGTGACCCGCCTGACC
TATTACGGTTATGAAAAATTGGCGATTAACCAAGGCAAACTGATTATTGAGGAAGCCAAGCGCTTATTTGATATCGAAAA
TGCGGTGGCGATTCATCGCATAGGGGCGTTAGAAATTGGTGATATGGCGGTGTGGGTCGGGGTGTCCTCTAAGCACCGTT
ATCCTGCCTTTGATGCTTGCAAATGGATATTAGATACCATTAAGGCCGATATTCCGGTATGGAAGCAAGAGTATTATCAA
GATGAGTCTTCTAAATGGCTAAGTAACAATGGTTAA

Upstream 100 bases:

>100_bases
GCCAGTTGGGATGATGTGATTAATGATGGCGATACCATTGCCTTTATTCCACCTGTGGCCGGTGGTTAGCCGTTTAGATA
AATAATTATTGGAGTAACAC

Downstream 100 bases:

>100_bases
GAAACAATGGCTAAGTAACAATGGCTAATAAAATAGAGTTAATTTAAGAAACTTAGTCTTAGATCCAATAACTAATAAAA
ATCCAGCTTATGCTGGATTT

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MDSQSALDTANQPHQQASSISHSVDEVYQLAQSQGFALLDEAIDAERLKDMLQDDQCGALATFEGWVRNHNNDSQVTRLT
YYGYEKLAINQGKLIIEEAKRLFDIENAVAIHRIGALEIGDMAVWVGVSSKHRYPAFDACKWILDTIKADIPVWKQEYYQ
DESSKWLSNNG

Sequences:

>Translated_171_residues
MDSQSALDTANQPHQQASSISHSVDEVYQLAQSQGFALLDEAIDAERLKDMLQDDQCGALATFEGWVRNHNNDSQVTRLT
YYGYEKLAINQGKLIIEEAKRLFDIENAVAIHRIGALEIGDMAVWVGVSSKHRYPAFDACKWILDTIKADIPVWKQEYYQ
DESSKWLSNNG
>Mature_171_residues
MDSQSALDTANQPHQQASSISHSVDEVYQLAQSQGFALLDEAIDAERLKDMLQDDQCGALATFEGWVRNHNNDSQVTRLT
YYGYEKLAINQGKLIIEEAKRLFDIENAVAIHRIGALEIGDMAVWVGVSSKHRYPAFDACKWILDTIKADIPVWKQEYYQ
DESSKWLSNNG

Specific function: Converts Molybdopterin Precursor Z Into Molybdopterin. This Requires The Incorporation Of Two Sulfur Atoms Into Precursor Z To Generate A Dithiolene Group. [C]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0717 [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=130, Percent_Identity=29.2307692307692, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1787003, Length=117, Percent_Identity=38.4615384615385, Blast_Score=82, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509279, Length=125, Percent_Identity=29.6, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356259, Length=134, Percent_Identity=29.1044776119403, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 19338; Mature: 19338

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSQSALDTANQPHQQASSISHSVDEVYQLAQSQGFALLDEAIDAERLKDMLQDDQCGAL
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCCH
ATFEGWVRNHNNDSQVTRLTYYGYEKLAINQGKLIIEEAKRLFDIENAVAIHRIGALEIG
HHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEC
DMAVWVGVSSKHRYPAFDACKWILDTIKADIPVWKQEYYQDESSKWLSNNG
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure
MDSQSALDTANQPHQQASSISHSVDEVYQLAQSQGFALLDEAIDAERLKDMLQDDQCGAL
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCCH
ATFEGWVRNHNNDSQVTRLTYYGYEKLAINQGKLIIEEAKRLFDIENAVAIHRIGALEIG
HHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEC
DMAVWVGVSSKHRYPAFDACKWILDTIKADIPVWKQEYYQDESSKWLSNNG
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]