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The map label for this gene is atoS [C]

Identifier: 148550825

GI number: 148550825

Start: 295901

End: 298189

Strand: Reverse

Name: atoS [C]

Synonym: Swit_5389

Alternate gene names: 148550825

Gene position: 298189-295901 (Counterclockwise)

Preceding gene: 148550826

Following gene: 148550824

Centisome position: 96.12

GC content: 64.7

Gene sequence:

>2289_bases
GTGCCTGAGGCTCCGTTTCCGCCTTTGCTCGCCGAGGTCCAGTTTCGCGCGGCAGCCCAGGCTCTGCCCGGCCATGTCTG
GACCGCGACGCCCGCCGGCGCCGCCGATTGGTTCAATGACCCGCTCTTGTCCTATACCGGACGCACATCGGACGATCTGC
TCGGGGACAAGTGGCTCTCGATCGTCCATCCCAATGATCGCGCGGGCGCGGCGCAATGCTGGAAGCAGGCGCTCGGCTCC
GGCGCGGTCTATGATGCCGAGTTTCGCATTCAGCGCCACGACGGCGCCTGGATTTGGCACCAGGTGCGCGGCACCCCGAT
CCGCGATGCGGACGGCGCCATTGAGCGATGGGTCGGGAGCACGATAGACTGCAACCAGCAAAAGCTCATTGAGCTTGCGG
CCGATCGCGACAGGCTATGGTCGCTCTCACGCGACCTGATGCTGGTATGCACCTTCGACGGTGTGATCACGGCCATCAAC
CCGAGCGCCACCACCATGCTGGGATGGAGCGAGGATGAGATGGTCGGACGGCCGCTTGCCGAGTTCATTCATCCTCAGGA
CGTCGCGGCGACCGCCGCCCAGGTCGCAAAGCTGGCGCGCGGGACAGATACCCTGTCGTTCGAGAACCGTTACCGGGCGC
GGAGCGGTGACTATCACCTTCTGGCCTGGACGGCGGTCCCCGCCGCCGACCGTATCCACGCGGTCGGCCGCGACGTGACC
GCCGAACGGGAGGTTGTGCGCGACCGGGAGAGGATCTGGGCACTCTCGCCCGTGCTCAAGCTCGTCACCGATCGGCAAGG
CATCATCGTCGACGTCAATCCGACCCGGACGAAAGTGCTGGGCTGGACGCGAGAGGAAGCCGTCGGCAAGTGCAGCGCCG
AGTTCATCGTGGGCGACGACATGGCATGGGCCAAGCAGATCGACAGGCTGGCCTCCGGGATCCCGCTCGAGGAATATCGC
ACTGTCCTCTTTGCCCGCGACGGTGCCAATCGCCTGATCCAGTGGACGACCGTTCCGGATGCCGGGAAATTCTATGGCTT
CGGCCGTGACATAACGGCCGAAGTCGAAGGCGCGAAAGCGCTGGGCGAAGCCGAAGAAGCCCTGCGCCAGGCGCAGAAAA
TGGAAGCGGTCGGACAGTTGACCGGCGGCATCGCCCATGACTTCAACAATCTGCTGCAAGGCATCAGCGGCAGTCTCGAC
ATCATGCGGCGCAGGATTGCCCAGAACCGACTGGGTGACATGGACCGCCTGATCACAATGGCGTCCGACGCTTCGGCCCG
CGCTGCGGCGCTGACCCATCGCCTGCTCGCCTTCTCCCGTCGTCAGCCCCTCGATCCCAAGCCAGTCGCGATCAACAGCC
TTATCCACTCACTCGAAGACATGGTTCGCCGCACGCTCGATGCGGGCATCTCGCTGCGTCTCTCGCTGGCGTCCGATCTG
TGGACCGCGAAATGCGATCCCAACCAACTCGAAAATGCGCTGCTCAATCTCGTGATCAACGCGCGAGATGCGATGCCCGC
CGGCGGAACGCTGACCATCGCGACCCGCAACGTGAGCTTCGAGGCCCCCCTGTCCGAACAGGGCGCAAAGCCCGGGCGAT
ATGTCGGATTGGCGGTTACCGACACCGGGGTCGGCATGGACGCGGAAACCGTCCGGCGCGCCTTTGAACCGTTTTTCACC
ACCAAGGCCATGGGCCAGGGCACGGGTCTCGGCCTCTCCATGGTCTACGGCTTTGCAAGGCAATCCGAAGGCCATGCCGC
CATCGACAGCGCCCCGGGCGACGGAACGACATTCCACCTCTATCTCCCCTATCATGCCGCCGCGCTCGAACCGGAGACGG
CGCCCGATGGACCCTGCCTGACAGCTGTCGCGGAAGTGGGCGAAGTGGTGCTCGTGGTGGAAGATGAAGCGATCGTGCGG
ACTTTGGTGGTCGATCAGCTTAGAGAGCTGGGCTATCATGTGCTCCAGGCAGCGGATGGACCCGAAGGCGTGGACATCCT
CAACTCGTCGCAGGTCATCAACCTGCTTCTCACCGACATAGGGCTTCCCGGGATGAACGGGCGCCTGGTCGCCCAAGCGG
GCCGGACCTGCCGCCCCGATCTCCCGATCCTGTTCATGACGGGCTATGCGGAGACGGCGACGCAGGCCGCCGGCTTTCTC
GAGCCAGGCATGGGTCTGATCACCAAGCCTTTTGAAATGGAGGTGCTCGCCCAGCGGGTGCGCGAAACGATGACCCAGGC
GCCCTTGCGCGCCGAGGCGCCAAGTGGTCCCGCGAAGGCGCCAATCTGA

Upstream 100 bases:

>100_bases
AGCTTCCGGCACGCCTGTTCGTCGGAGCGCGATCTGGAGTTTACGAAACACAAACGGGGGGCCACGACGGTGCGACTCAC
ATCAAGCGGGGGTGTAGAGC

Downstream 100 bases:

>100_bases
GCCCACCTGCGACAAGTTAACCGGAATTTAGCCGCGCACGGGGCAAGTCTCGCGGGGAGGTATCATGAAGCGCCGGATTG
CCATCGATCAGATTGAAGCT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MPEAPFPPLLAEVQFRAAAQALPGHVWTATPAGAADWFNDPLLSYTGRTSDDLLGDKWLSIVHPNDRAGAAQCWKQALGS
GAVYDAEFRIQRHDGAWIWHQVRGTPIRDADGAIERWVGSTIDCNQQKLIELAADRDRLWSLSRDLMLVCTFDGVITAIN
PSATTMLGWSEDEMVGRPLAEFIHPQDVAATAAQVAKLARGTDTLSFENRYRARSGDYHLLAWTAVPAADRIHAVGRDVT
AEREVVRDRERIWALSPVLKLVTDRQGIIVDVNPTRTKVLGWTREEAVGKCSAEFIVGDDMAWAKQIDRLASGIPLEEYR
TVLFARDGANRLIQWTTVPDAGKFYGFGRDITAEVEGAKALGEAEEALRQAQKMEAVGQLTGGIAHDFNNLLQGISGSLD
IMRRRIAQNRLGDMDRLITMASDASARAAALTHRLLAFSRRQPLDPKPVAINSLIHSLEDMVRRTLDAGISLRLSLASDL
WTAKCDPNQLENALLNLVINARDAMPAGGTLTIATRNVSFEAPLSEQGAKPGRYVGLAVTDTGVGMDAETVRRAFEPFFT
TKAMGQGTGLGLSMVYGFARQSEGHAAIDSAPGDGTTFHLYLPYHAAALEPETAPDGPCLTAVAEVGEVVLVVEDEAIVR
TLVVDQLRELGYHVLQAADGPEGVDILNSSQVINLLLTDIGLPGMNGRLVAQAGRTCRPDLPILFMTGYAETATQAAGFL
EPGMGLITKPFEMEVLAQRVRETMTQAPLRAEAPSGPAKAPI

Sequences:

>Translated_762_residues
MPEAPFPPLLAEVQFRAAAQALPGHVWTATPAGAADWFNDPLLSYTGRTSDDLLGDKWLSIVHPNDRAGAAQCWKQALGS
GAVYDAEFRIQRHDGAWIWHQVRGTPIRDADGAIERWVGSTIDCNQQKLIELAADRDRLWSLSRDLMLVCTFDGVITAIN
PSATTMLGWSEDEMVGRPLAEFIHPQDVAATAAQVAKLARGTDTLSFENRYRARSGDYHLLAWTAVPAADRIHAVGRDVT
AEREVVRDRERIWALSPVLKLVTDRQGIIVDVNPTRTKVLGWTREEAVGKCSAEFIVGDDMAWAKQIDRLASGIPLEEYR
TVLFARDGANRLIQWTTVPDAGKFYGFGRDITAEVEGAKALGEAEEALRQAQKMEAVGQLTGGIAHDFNNLLQGISGSLD
IMRRRIAQNRLGDMDRLITMASDASARAAALTHRLLAFSRRQPLDPKPVAINSLIHSLEDMVRRTLDAGISLRLSLASDL
WTAKCDPNQLENALLNLVINARDAMPAGGTLTIATRNVSFEAPLSEQGAKPGRYVGLAVTDTGVGMDAETVRRAFEPFFT
TKAMGQGTGLGLSMVYGFARQSEGHAAIDSAPGDGTTFHLYLPYHAAALEPETAPDGPCLTAVAEVGEVVLVVEDEAIVR
TLVVDQLRELGYHVLQAADGPEGVDILNSSQVINLLLTDIGLPGMNGRLVAQAGRTCRPDLPILFMTGYAETATQAAGFL
EPGMGLITKPFEMEVLAQRVRETMTQAPLRAEAPSGPAKAPI
>Mature_761_residues
PEAPFPPLLAEVQFRAAAQALPGHVWTATPAGAADWFNDPLLSYTGRTSDDLLGDKWLSIVHPNDRAGAAQCWKQALGSG
AVYDAEFRIQRHDGAWIWHQVRGTPIRDADGAIERWVGSTIDCNQQKLIELAADRDRLWSLSRDLMLVCTFDGVITAINP
SATTMLGWSEDEMVGRPLAEFIHPQDVAATAAQVAKLARGTDTLSFENRYRARSGDYHLLAWTAVPAADRIHAVGRDVTA
EREVVRDRERIWALSPVLKLVTDRQGIIVDVNPTRTKVLGWTREEAVGKCSAEFIVGDDMAWAKQIDRLASGIPLEEYRT
VLFARDGANRLIQWTTVPDAGKFYGFGRDITAEVEGAKALGEAEEALRQAQKMEAVGQLTGGIAHDFNNLLQGISGSLDI
MRRRIAQNRLGDMDRLITMASDASARAAALTHRLLAFSRRQPLDPKPVAINSLIHSLEDMVRRTLDAGISLRLSLASDLW
TAKCDPNQLENALLNLVINARDAMPAGGTLTIATRNVSFEAPLSEQGAKPGRYVGLAVTDTGVGMDAETVRRAFEPFFTT
KAMGQGTGLGLSMVYGFARQSEGHAAIDSAPGDGTTFHLYLPYHAAALEPETAPDGPCLTAVAEVGEVVLVVEDEAIVRT
LVVDQLRELGYHVLQAADGPEGVDILNSSQVINLLLTDIGLPGMNGRLVAQAGRTCRPDLPILFMTGYAETATQAAGFLE
PGMGLITKPFEMEVLAQRVRETMTQAPLRAEAPSGPAKAPI

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=351, Percent_Identity=27.3504273504274, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=30.5220883534137, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI145693157, Length=282, Percent_Identity=25.531914893617, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87081816, Length=402, Percent_Identity=25.1243781094527, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788713, Length=290, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=245, Percent_Identity=29.3877551020408, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=449, Percent_Identity=23.3853006681514, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=35.042735042735, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82599; Mature: 82468

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAPFPPLLAEVQFRAAAQALPGHVWTATPAGAADWFNDPLLSYTGRTSDDLLGDKWLS
CCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHCCCCHHHCCCCCCCHHHCCCEEE
IVHPNDRAGAAQCWKQALGSGAVYDAEFRIQRHDGAWIWHQVRGTPIRDADGAIERWVGS
EECCCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHCCC
TIDCNQQKLIELAADRDRLWSLSRDLMLVCTFDGVITAINPSATTMLGWSEDEMVGRPLA
CCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEECCEEEEECCCCEEEECCCCHHHHCCHHH
EFIHPQDVAATAAQVAKLARGTDTLSFENRYRARSGDYHLLAWTAVPAADRIHAVGRDVT
HHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCEEEEEEEECCCHHHHHHHCCCCH
AEREVVRDRERIWALSPVLKLVTDRQGIIVDVNPTRTKVLGWTREEAVGKCSAEFIVGDD
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCHHHHHCCCCCEEEECCC
MAWAKQIDRLASGIPLEEYRTVLFARDGANRLIQWTTVPDAGKFYGFGRDITAEVEGAKA
HHHHHHHHHHHCCCCHHHHHEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEECCCHHH
LGEAEEALRQAQKMEAVGQLTGGIAHDFNNLLQGISGSLDIMRRRIAQNRLGDMDRLITM
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHH
ASDASARAAALTHRLLAFSRRQPLDPKPVAINSLIHSLEDMVRRTLDAGISLRLSLASDL
HCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
WTAKCDPNQLENALLNLVINARDAMPAGGTLTIATRNVSFEAPLSEQGAKPGRYVGLAVT
EECCCCHHHHHHHHHHHHEECCCCCCCCCEEEEEEECEEECCCHHHCCCCCCCEEEEEEE
DTGVGMDAETVRRAFEPFFTTKAMGQGTGLGLSMVYGFARQSEGHAAIDSAPGDGTTFHL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEE
YLPYHAAALEPETAPDGPCLTAVAEVGEVVLVVEDEAIVRTLVVDQLRELGYHVLQAADG
EECCCCEECCCCCCCCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
PEGVDILNSSQVINLLLTDIGLPGMNGRLVAQAGRTCRPDLPILFMTGYAETATQAAGFL
CCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEECCHHHHHHHHCCC
EPGMGLITKPFEMEVLAQRVRETMTQAPLRAEAPSGPAKAPI
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PEAPFPPLLAEVQFRAAAQALPGHVWTATPAGAADWFNDPLLSYTGRTSDDLLGDKWLS
CCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHCCCCHHHCCCCCCCHHHCCCEEE
IVHPNDRAGAAQCWKQALGSGAVYDAEFRIQRHDGAWIWHQVRGTPIRDADGAIERWVGS
EECCCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHCCC
TIDCNQQKLIELAADRDRLWSLSRDLMLVCTFDGVITAINPSATTMLGWSEDEMVGRPLA
CCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEECCEEEEECCCCEEEECCCCHHHHCCHHH
EFIHPQDVAATAAQVAKLARGTDTLSFENRYRARSGDYHLLAWTAVPAADRIHAVGRDVT
HHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCEEEEEEEECCCHHHHHHHCCCCH
AEREVVRDRERIWALSPVLKLVTDRQGIIVDVNPTRTKVLGWTREEAVGKCSAEFIVGDD
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCHHHHHCCCCCEEEECCC
MAWAKQIDRLASGIPLEEYRTVLFARDGANRLIQWTTVPDAGKFYGFGRDITAEVEGAKA
HHHHHHHHHHHCCCCHHHHHEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEECCCHHH
LGEAEEALRQAQKMEAVGQLTGGIAHDFNNLLQGISGSLDIMRRRIAQNRLGDMDRLITM
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHH
ASDASARAAALTHRLLAFSRRQPLDPKPVAINSLIHSLEDMVRRTLDAGISLRLSLASDL
HCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
WTAKCDPNQLENALLNLVINARDAMPAGGTLTIATRNVSFEAPLSEQGAKPGRYVGLAVT
EECCCCHHHHHHHHHHHHEECCCCCCCCCEEEEEEECEEECCCHHHCCCCCCCEEEEEEE
DTGVGMDAETVRRAFEPFFTTKAMGQGTGLGLSMVYGFARQSEGHAAIDSAPGDGTTFHL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEE
YLPYHAAALEPETAPDGPCLTAVAEVGEVVLVVEDEAIVRTLVVDQLRELGYHVLQAADG
EECCCCEECCCCCCCCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
PEGVDILNSSQVINLLLTDIGLPGMNGRLVAQAGRTCRPDLPILFMTGYAETATQAAGFL
CCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEECCHHHHHHHHCCC
EPGMGLITKPFEMEVLAQRVRETMTQAPLRAEAPSGPAKAPI
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA