Click here to switch to the map view.

The map label for this gene is yhdY [H]

Identifier: 148550726

GI number: 148550726

Start: 190276

End: 191391

Strand: Direct

Name: yhdY [H]

Synonym: Swit_5290

Alternate gene names: 148550726

Gene position: 190276-191391 (Clockwise)

Preceding gene: 148550725

Following gene: 148550728

Centisome position: 61.33

GC content: 61.11

Gene sequence:

>1116_bases
ATGGATCCACGTTTCAGTTTTGACCGAATGATCGACGAGGCCACGCATTGGATCGGGGCCAACTGGCTCGAGATCGCGAT
TGCCACCGCCGCGGGCGCGGCGATCTATCTGCTGCTCAACCTTGTGCGCGGATGGAGTGTAAAACTGTGCCAGCGGGGCG
AAGGCGCGGCGAGCTGGTACAGTATCCTGGGGCGAGCCTTCGGACGTACCGGGCAGATCTTCATGATCCTTGTCGCCGCC
CGGCTCGTAGTGGGATACGCCGACGCACCGGCCTGGCTGACTACCACGGTCGCCACTTTGTTCACGATCTCCGCGGTATT
CCAGGGCGCGCTATGGGCCCGAGAAGTCGTCTTCGGAGCGATCGAGCATCGCATGCGCGACCAGGAGCATAACAGTCGGG
CACTCATGAGCGCCCTTGGCATCATACGGCTCCTTGTGACGATCTCCCTCTTCGCGATCGCGCTCGTGGTGGTGCTGAGC
AATCTGGGGGTGAACGTCACCGGGCTGGTTACGGGCCTTGGGATTGGCGGCATCGCGATTGGCCTCGCGGCACAAGGCAT
TTTCGCCGACTTGTTCGCAGCGCTCGCCATTCTTTTCGACCGCCCGTTTCGCATTGGCGATTCCATTTCCTATGACAAGG
GCGCCGGCTCGGGGACAGTTGAATCGATCGGTCTCAAGTCGACGCGGATTCGCGGCGGGCCCGGCGAAGAGCGGATTATC
GCGAACAAGAAGCTGCTGGACTTCGAAATCCTCAACACGACCCGACGCCTGCGCAACCGTTTCAAGTTCGAGTTTGTGAT
TGGGTACGCTGCGGCGCCGGAAGTCATCCTCAAGATACCGGGTCTGCTGAAGGACGCGGTCGAAAGCGAAGGCTACACCC
TCATACATGGCGGGGTGAACGGCTTCGTCTCAAGCGGCATCAGCTACGACGTCGAGTTCGAGTCGAAAGAAGCAGACTTC
CCGGCCGATGCACGAGACAGGGTGACCGCGGCGATACTGTCGCGCTTTCGCGATAATGACATCAGCTTCGCTTACCCGAC
CCAGGTGAACTTGCTCGCCGAGAAGACGAAGCCAGACCCGCCCGCGCAGGTCAGGGAAGAGAGCGGACGGGCGTGA

Upstream 100 bases:

>100_bases
GCCTGACGCACGGTGAGGGTACAGAGCAAAACCAGCGGGAACCCCCCACGCTCTTTCGGGATTTCGGACAGCGCCAGCAA
CGAGCGGACGTGTTTGTCAG

Downstream 100 bases:

>100_bases
CGGCGGCCGGCAACGCGCGCGGGTGACGTATCGCGCCAGGGGAACGCCGGCTCTTGGCGAGATTCGTCGCGCAACGACCG
CAAAAGTCTCGCCAGCTGTG

Product: MscS mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MDPRFSFDRMIDEATHWIGANWLEIAIATAAGAAIYLLLNLVRGWSVKLCQRGEGAASWYSILGRAFGRTGQIFMILVAA
RLVVGYADAPAWLTTTVATLFTISAVFQGALWAREVVFGAIEHRMRDQEHNSRALMSALGIIRLLVTISLFAIALVVVLS
NLGVNVTGLVTGLGIGGIAIGLAAQGIFADLFAALAILFDRPFRIGDSISYDKGAGSGTVESIGLKSTRIRGGPGEERII
ANKKLLDFEILNTTRRLRNRFKFEFVIGYAAAPEVILKIPGLLKDAVESEGYTLIHGGVNGFVSSGISYDVEFESKEADF
PADARDRVTAAILSRFRDNDISFAYPTQVNLLAEKTKPDPPAQVREESGRA

Sequences:

>Translated_371_residues
MDPRFSFDRMIDEATHWIGANWLEIAIATAAGAAIYLLLNLVRGWSVKLCQRGEGAASWYSILGRAFGRTGQIFMILVAA
RLVVGYADAPAWLTTTVATLFTISAVFQGALWAREVVFGAIEHRMRDQEHNSRALMSALGIIRLLVTISLFAIALVVVLS
NLGVNVTGLVTGLGIGGIAIGLAAQGIFADLFAALAILFDRPFRIGDSISYDKGAGSGTVESIGLKSTRIRGGPGEERII
ANKKLLDFEILNTTRRLRNRFKFEFVIGYAAAPEVILKIPGLLKDAVESEGYTLIHGGVNGFVSSGISYDVEFESKEADF
PADARDRVTAAILSRFRDNDISFAYPTQVNLLAEKTKPDPPAQVREESGRA
>Mature_371_residues
MDPRFSFDRMIDEATHWIGANWLEIAIATAAGAAIYLLLNLVRGWSVKLCQRGEGAASWYSILGRAFGRTGQIFMILVAA
RLVVGYADAPAWLTTTVATLFTISAVFQGALWAREVVFGAIEHRMRDQEHNSRALMSALGIIRLLVTISLFAIALVVVLS
NLGVNVTGLVTGLGIGGIAIGLAAQGIFADLFAALAILFDRPFRIGDSISYDKGAGSGTVESIGLKSTRIRGGPGEERII
ANKKLLDFEILNTTRRLRNRFKFEFVIGYAAAPEVILKIPGLLKDAVESEGYTLIHGGVNGFVSSGISYDVEFESKEADF
PADARDRVTAAILSRFRDNDISFAYPTQVNLLAEKTKPDPPAQVREESGRA

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=283, Percent_Identity=29.3286219081272, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787591, Length=251, Percent_Identity=25.4980079681275, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786670, Length=239, Percent_Identity=27.1966527196653, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 40184; Mature: 40184

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPRFSFDRMIDEATHWIGANWLEIAIATAAGAAIYLLLNLVRGWSVKLCQRGEGAASWY
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCHHHHH
SILGRAFGRTGQIFMILVAARLVVGYADAPAWLTTTVATLFTISAVFQGALWAREVVFGA
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEHRMRDQEHNSRALMSALGIIRLLVTISLFAIALVVVLSNLGVNVTGLVTGLGIGGIAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHH
GLAAQGIFADLFAALAILFDRPFRIGDSISYDKGAGSGTVESIGLKSTRIRGGPGEERII
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEE
ANKKLLDFEILNTTRRLRNRFKFEFVIGYAAAPEVILKIPGLLKDAVESEGYTLIHGGVN
ECCCHHHHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHCCHHHHHHHCCCCEEEEECCHH
GFVSSGISYDVEFESKEADFPADARDRVTAAILSRFRDNDISFAYPTQVNLLAEKTKPDP
HHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCHHEECCCCCCC
PAQVREESGRA
CHHHHHCCCCC
>Mature Secondary Structure
MDPRFSFDRMIDEATHWIGANWLEIAIATAAGAAIYLLLNLVRGWSVKLCQRGEGAASWY
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCCHHHHH
SILGRAFGRTGQIFMILVAARLVVGYADAPAWLTTTVATLFTISAVFQGALWAREVVFGA
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEHRMRDQEHNSRALMSALGIIRLLVTISLFAIALVVVLSNLGVNVTGLVTGLGIGGIAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHH
GLAAQGIFADLFAALAILFDRPFRIGDSISYDKGAGSGTVESIGLKSTRIRGGPGEERII
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEE
ANKKLLDFEILNTTRRLRNRFKFEFVIGYAAAPEVILKIPGLLKDAVESEGYTLIHGGVN
ECCCHHHHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHCCHHHHHHHCCCCEEEEECCHH
GFVSSGISYDVEFESKEADFPADARDRVTAAILSRFRDNDISFAYPTQVNLLAEKTKPDP
HHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCHHEECCCCCCC
PAQVREESGRA
CHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]