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The map label for this gene is trpD [H]

Identifier: 148360520

GI number: 148360520

Start: 1019366

End: 1020400

Strand: Reverse

Name: trpD [H]

Synonym: LPC_2461

Alternate gene names: 148360520

Gene position: 1020400-1019366 (Counterclockwise)

Preceding gene: 148360519

Following gene: 148360521

Centisome position: 28.53

GC content: 40.29

Gene sequence:

>1035_bases
ATGAAACCCAAACTTCTATTTGAACAACTTCTATCCCGACAGGATTTAAGCTCAGACCAGATGCAAGAGGTCATCCATGC
TTGTATGACAGGTGAATTTAGTGATGTGCAAATTGCAACCTTTCTGGCATTAATGCGCATGAAAAGTGAGACAGTCAATG
AACTTACTGCAGCAGCTAAAGTCATGAGGCAATTAGCCCACAAAATAGATTTGGGAAATCCCCTGATTGATATAGTTGGC
ACTGGCGGTGATGGAAGAAATACTTTTAACGTATCAACAGCCTGTAGTTTTGTTGTAGCTGCAGCAGGAATAAAAGTTGC
AAAGCATGGTAACCGTTCTGTTTCGAGTCGTAGCGGTAGCGCTGATCTATTAGAACAAGCCGGATTTATACTTAATCTTT
CTGACTCACAGGTACAAAACTGCATCAACCAATGTCAATTGGCTTTCTTGTTTGCGCCACATTATCACCCCGCCATGCAG
CATGCGAGAGCTGCAAGGCAACAATTAGGAATAAGAACTTTATTTAATTTACTTGGCCCACTGATTAACCCGGCTCAGGT
AAAACGACAAGTCGTTGGTGTATTTTCAACGAATTGGCTCAAAACAATAGCTACTGTCCTGGCCAACTTAGGTAGTGAAA
GATCATTAGTAATAAGCTCTCAAGATGGACTGGATGAGATTAGTATTGCAGCGAAAAGTGAAGTAGTTGAATACCGAGAT
GGAAATTTTAAGCAATGGTTTATTTCTCCTGAAGATTATGGTCTAAAGCATTCTTCTTTAGATGCAATCATAGTCGACTC
ACCAGAGCAAAGCCTGCATTTGATTCAATCCGTACTTTCAGGTGATTCTGGGCCAGCTCGAGATATAGTCCTTCTCAATT
CTGCCGCAGCCATTTATTGTGCCAAAGATGGCATATCGTTTGATGCATCCATAGAGGAAGCAAGAATTGCGATTGATAGT
GGTAAAGCAAATCATTGTTTTAACAAACTCCGATTATTGACCCAAACTTTAAATAAAGAATCAAATCATGAATAG

Upstream 100 bases:

>100_bases
GCAATATCACATCGTCAATTTCCTCTTTTTGGTCTACAATTTCATCCTGAAGCCATATTAAGTCAATTTGGCTTGCAAAT
ACTCGAGAATTTTTTACGCT

Downstream 100 bases:

>100_bases
TATCCTGGAACGAATAGCCAAACATAAACTAGAAGAAGTTGCAGTTGCGAAAAAAAATAAGCCTTTACATGTTCTGTCAA
AACAACAACCGGGGGAAATA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKSETVNELTAAAKVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDASIEEARIAIDS
GKANHCFNKLRLLTQTLNKESNHE

Sequences:

>Translated_344_residues
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKSETVNELTAAAKVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDASIEEARIAIDS
GKANHCFNKLRLLTQTLNKESNHE
>Mature_344_residues
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKSETVNELTAAAKVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDASIEEARIAIDS
GKANHCFNKLRLLTQTLNKESNHE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=277, Percent_Identity=40.7942238267148, Blast_Score=195, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6320561, Length=351, Percent_Identity=31.3390313390313, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37435; Mature: 37435

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKSETVNELTAAAK
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VMRQLAHKIDLGNPLIDIVGTGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGS
HHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQHARAARQQLGIRTLFNLLGP
HHHHHHCCCEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYC
CCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEE
AKDGISFDASIEEARIAIDSGKANHCFNKLRLLTQTLNKESNHE
ECCCCCCCCCHHHHEEEEECCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPKLLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKSETVNELTAAAK
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VMRQLAHKIDLGNPLIDIVGTGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGS
HHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQHARAARQQLGIRTLFNLLGP
HHHHHHCCCEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYC
CCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEE
AKDGISFDASIEEARIAIDSGKANHCFNKLRLLTQTLNKESNHE
ECCCCCCCCCHHHHEEEEECCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA