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The map label for this gene is trpG [H]

Identifier: 148360519

GI number: 148360519

Start: 1020378

End: 1020956

Strand: Reverse

Name: trpG [H]

Synonym: LPC_2460

Alternate gene names: 148360519

Gene position: 1020956-1020378 (Counterclockwise)

Preceding gene: 148360518

Following gene: 148360520

Centisome position: 28.55

GC content: 38.86

Gene sequence:

>579_bases
ATGTTACTAATTATTGATAACTACGATTCATTTACATACAACCTGGTACAGTACTTCCAGAGCTTAAATCAAAAAGTTGC
AGTTTTTAAAAATGACGAAATTCAAATCGATGCTATCAGGCAATCAGCGCCGCAATACCTGGTCATTTCACCGGGACCCA
ACTCTCCTGATGAATCAGGAATCTCTATAGAAGTCATTAAAGAGTTTCACAAGCATATTCCGATATTGGGTATTTGCCTT
GGCCATCAGTGTATAGCTCAGGCATTTGGAGGCAAAATCATCCCAGCACCAGAAATCATGCATGGTAAAACCTCAGAAAT
CACCCATCATTACCAGGGCTTATTTACAGGAATACCAAATCACTTTCAAGCGACGAGATATCATTCTTTAGCCGTGGATA
TCATGAGCTTGCCCAATTGCTTTTCGATAGATGCGTGGGCAGACGATACAATAATGGCAATATCACATCGTCAATTTCCT
CTTTTTGGTCTACAATTTCATCCTGAAGCCATATTAAGTCAATTTGGCTTGCAAATACTCGAGAATTTTTTACGCTATGA
AACCCAAACTTCTATTTGA

Upstream 100 bases:

>100_bases
CCCCAAAGCAATACTTGCCAATCAACAAGTAAGGCAAGTTTATTTGGGTGAAGAATTTGCTTTGTAGCCTCATTTAAAAG
AATACATTTTAATTATACTT

Downstream 100 bases:

>100_bases
ACAACTTCTATCCCGACAGGATTTAAGCTCAGACCAGATGCAAGAGGTCATCCATGCTTGTATGACAGGTGAATTTAGTG
ATGTGCAAATTGCAACCTTT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLLIIDNYDSFTYNLVQYFQSLNQKVAVFKNDEIQIDAIRQSAPQYLVISPGPNSPDESGISIEVIKEFHKHIPILGICL
GHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPNHFQATRYHSLAVDIMSLPNCFSIDAWADDTIMAISHRQFP
LFGLQFHPEAILSQFGLQILENFLRYETQTSI

Sequences:

>Translated_192_residues
MLLIIDNYDSFTYNLVQYFQSLNQKVAVFKNDEIQIDAIRQSAPQYLVISPGPNSPDESGISIEVIKEFHKHIPILGICL
GHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPNHFQATRYHSLAVDIMSLPNCFSIDAWADDTIMAISHRQFP
LFGLQFHPEAILSQFGLQILENFLRYETQTSI
>Mature_192_residues
MLLIIDNYDSFTYNLVQYFQSLNQKVAVFKNDEIQIDAIRQSAPQYLVISPGPNSPDESGISIEVIKEFHKHIPILGICL
GHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPNHFQATRYHSLAVDIMSLPNCFSIDAWADDTIMAISHRQFP
LFGLQFHPEAILSQFGLQILENFLRYETQTSI

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=55.6756756756757, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=38.2198952879581, Blast_Score=144, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=42.9319371727749, Blast_Score=169, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=31.1004784688995, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21703; Mature: 21703

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIIDNYDSFTYNLVQYFQSLNQKVAVFKNDEIQIDAIRQSAPQYLVISPGPNSPDESG
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCCCEEEECCCCCCCCCCC
ISIEVIKEFHKHIPILGICLGHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPN
CCHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCC
HFQATRYHSLAVDIMSLPNCFSIDAWADDTIMAISHRQFPLFGLQFHPEAILSQFGLQIL
CHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCEECEEECHHHHHHHHHHHHH
ENFLRYETQTSI
HHHHHHHHHCCC
>Mature Secondary Structure
MLLIIDNYDSFTYNLVQYFQSLNQKVAVFKNDEIQIDAIRQSAPQYLVISPGPNSPDESG
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCEEEEEECCCCCCEEEECCCCCCCCCCC
ISIEVIKEFHKHIPILGICLGHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPN
CCHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCC
HFQATRYHSLAVDIMSLPNCFSIDAWADDTIMAISHRQFPLFGLQFHPEAILSQFGLQIL
CHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCEECEEECHHHHHHHHHHHHH
ENFLRYETQTSI
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]