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The map label for this gene is pilE [H]

Identifier: 148359462

GI number: 148359462

Start: 2228476

End: 2228889

Strand: Reverse

Name: pilE [H]

Synonym: LPC_1369

Alternate gene names: 148359462

Gene position: 2228889-2228476 (Counterclockwise)

Preceding gene: 148359465

Following gene: 148359461

Centisome position: 62.32

GC content: 47.34

Gene sequence:

>414_bases
ATGAGACAAAAGGGTTTTACATTAATTGAATTGATGATAGTCGTAGCGATTATCGGTATTTTGGCAGCAATCGCTATACC
AGCCTATCAAGATTACACCATACGAGCTCGTGTAAGCGAGGGGCTACAGATGGCAAGCTCAGCCAAACTAGCCGTATCTG
AAACGGCTATTACAAATAATGCGTTACCAACTACTCAGGCTGAAACGGGCTACGAGTCTCCTGCCCCCACGGCTAATGTG
ACAGGTATTGCAATAGGTGCTAACGGCGTGATTACCATCACGTATACCCCTGCAGCAGGTGATGGTACGATTATTATGAC
TCCTACACTGGATGCCAACAACGGTGATGTTACCTGGAACTGCACCGGTGGTAGCTTATCGCCTAAATACCGGCCTGCCA
GTTGCAGACCATAA

Upstream 100 bases:

>100_bases
TGATTATTTAACATGTAAAATAATATTGGTTTAGAATATACACTGGTAGTTGGCATTATGCTTGCATGATACTAATGGAT
AGTTAACTATGGAGATAGCC

Downstream 100 bases:

>100_bases
TTAGGATAAATCAACCTATTAAAACCGCCTCGCAATGGCGGTTTTTTTTATTTGTTTAAGCTTTGCTAATGAGTTATTTG
CCTGACATGAATATCTAGAG

Product: Tfp pilus assembly protein, major type IV pilin class A

Products: NA

Alternate protein names: MS11 antigen; Pilin [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNNALPTTQAETGYESPAPTANV
TGIAIGANGVITITYTPAAGDGTIIMTPTLDANNGDVTWNCTGGSLSPKYRPASCRP

Sequences:

>Translated_137_residues
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNNALPTTQAETGYESPAPTANV
TGIAIGANGVITITYTPAAGDGTIIMTPTLDANNGDVTWNCTGGSLSPKYRPASCRP
>Mature_137_residues
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNNALPTTQAETGYESPAPTANV
TGIAIGANGVITITYTPAAGDGTIIMTPTLDANNGDVTWNCTGGSLSPKYRPASCRP

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=123, Percent_Identity=39.0243902439024, Blast_Score=81, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 14173; Mature: 14173

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCHHHHCCCCEEEEEEEECCC
ALPTTQAETGYESPAPTANVTGIAIGANGVITITYTPAAGDGTIIMTPTLDANNGDVTWN
CCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEE
CTGGSLSPKYRPASCRP
ECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCHHHHCCCCEEEEEEEECCC
ALPTTQAETGYESPAPTANVTGIAIGANGVITITYTPAAGDGTIIMTPTLDANNGDVTWN
CCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEE
CTGGSLSPKYRPASCRP
ECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6148752; 2872674; 1671354; 1348857; 6143785; 7477282; 10048019 [H]