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The map label for this gene is pilE [H]

Identifier: 148359461

GI number: 148359461

Start: 2227861

End: 2228274

Strand: Reverse

Name: pilE [H]

Synonym: LPC_1368

Alternate gene names: 148359461

Gene position: 2228274-2227861 (Counterclockwise)

Preceding gene: 148359462

Following gene: 148359458

Centisome position: 62.3

GC content: 42.75

Gene sequence:

>414_bases
ATGAGAACGAAAGGATTTACTTTAATCGAGCTGATGATAGTTGCTGCTATCCTTGGGATTCTACTTGCCATCGCTTTTCC
AGCCTATCAGGACTATACCATCAGAGCGCGGGTGGCTGAAGGATTGGAAAAGGCTTCATTTGCAAAATTAGCCGTTGCCG
AGAAGATTTTGATAGATAATATATTGCCATTAAATCAAGCAGATACTAGTTACTCAAGTCCCATACCCACAGACAGTGTC
GCCTCTATAGCTATTGGCAATCAAGGCATAATTACCATTACCTACACGGCAAATGCAGGTAATGGCACTATTACAATGGT
TCCTACAATAGATGCCACTAACAGAATACTCACTTGGGATTGCACTGGTGGTACCCTGATTAGTAAATATCGTCCAGCCT
ACTGCCGCCCTTAA

Upstream 100 bases:

>100_bases
AAAAGGCGTATTGAGTCATTTAGGTTGCAGAGGAGTTTAAATTCATCAAGTTGGCATTGAATTTGCGTGATATCAGTTAG
ATGCAATGCCAGGTGGCGCT

Downstream 100 bases:

>100_bases
TCTTGATTGATTTTTTTAGCAACTAACTGGTTTTTTAGTCGGACATAATCTGGCAATCCATTTTTGTAATTTGGATAAGC
TTCACCTTGAATCAAAGGGG

Product: type IV pilin PilE

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MRTKGFTLIELMIVAAILGILLAIAFPAYQDYTIRARVAEGLEKASFAKLAVAEKILIDNILPLNQADTSYSSPIPTDSV
ASIAIGNQGIITITYTANAGNGTITMVPTIDATNRILTWDCTGGTLISKYRPAYCRP

Sequences:

>Translated_137_residues
MRTKGFTLIELMIVAAILGILLAIAFPAYQDYTIRARVAEGLEKASFAKLAVAEKILIDNILPLNQADTSYSSPIPTDSV
ASIAIGNQGIITITYTANAGNGTITMVPTIDATNRILTWDCTGGTLISKYRPAYCRP
>Mature_137_residues
MRTKGFTLIELMIVAAILGILLAIAFPAYQDYTIRARVAEGLEKASFAKLAVAEKILIDNILPLNQADTSYSSPIPTDSV
ASIAIGNQGIITITYTANAGNGTITMVPTIDATNRILTWDCTGGTLISKYRPAYCRP

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 14681; Mature: 14681

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTKGFTLIELMIVAAILGILLAIAFPAYQDYTIRARVAEGLEKASFAKLAVAEKILIDN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCHHHHHHHHHHHHHHHHHHC
ILPLNQADTSYSSPIPTDSVASIAIGNQGIITITYTANAGNGTITMVPTIDATNRILTWD
CCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEEE
CTGGTLISKYRPAYCRP
CCCCEEECCCCCCCCCC
>Mature Secondary Structure
MRTKGFTLIELMIVAAILGILLAIAFPAYQDYTIRARVAEGLEKASFAKLAVAEKILIDN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCHHHHHHHHHHHHHHHHHHC
ILPLNQADTSYSSPIPTDSVASIAIGNQGIITITYTANAGNGTITMVPTIDATNRILTWD
CCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEEE
CTGGTLISKYRPAYCRP
CCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2894335 [H]