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The map label for this gene is pyrH [H]

Identifier: 148359247

GI number: 148359247

Start: 1978111

End: 1978851

Strand: Reverse

Name: pyrH [H]

Synonym: LPC_1141

Alternate gene names: 148359247

Gene position: 1978851-1978111 (Counterclockwise)

Preceding gene: 148359248

Following gene: 148359246

Centisome position: 55.33

GC content: 42.65

Gene sequence:

>741_bases
ATGAATGAAAGTCAACCTAAATTAAAATACAAACGCATTCTGCTTAAATTTAGTGGTGAGGCGCTGATGGGGAAATCTCA
ATTTGGGATTGATCCTTCAGTTCTTGACTCATTAGCTCGAGACATAGCAGAATTAATTCATATGGGTGTGGAAGTTGGTT
TGGTTTTAGGTGGAGGCAATCTGTTCAGAGGGAAAGCGCTCTCTCAGGCGGGCGTAGGACGAGTGACAGGAGACCATATG
GGGATGCTGGCCACTGTTATGAATGCTTTGGCACTCCGTGATGCTTTGGAGCGAATTGATCTGCCCGCTCGTATTATGTC
AGCTATTCCAATGCTTGGGGTAGTTGACCCATACCATAGACGAAAAGCTATCACTCACTTGCGCAATGGTCAGGTGGTGA
TTTTTGCAGCTGGAACAGGAAATCCCTTTTTTACAACAGATACTGCTGCTTGTTTGAGGGCAATTGAGATAGGCGCAGAT
ATTGTTTTAAAAGCAACTAAGGTGGATGGAGTTTATTCTGCTGACCCACTTAAAAACTCTGATGCAAAGCGTTATGATTA
TTTGACTTACAAAGAAGTTTTAACCAAAGGTTTGGAAGTGATGGATTCCACTGCAATTTGTTTGTGCCAAGATCAGGGAA
TGCCTTTACAGGTGTTTGATATGGCGGCTCCTAAAGCATTAAAACGAATTGTAACTGGAGAACGAGTAGGAACTATAGTC
GGAGCTAATCATGATCAATGA

Upstream 100 bases:

>100_bases
ATGCTGAAGTAATATCCTTTGTTCGTTATGAAGTAGGGGAAGGAATAGAGAAAAAAGAGGACAATTTTGTTGAAGAAGTG
ATGGCTCAGGTTCGTACATG

Downstream 100 bases:

>100_bases
GATTAAGCAAGATTCAGAAAAACGCATGAAAAAGACTATTGAGGCTTTGCATACGGATATGTCAAAAATCCGTACCGGCA
GGGCGAATGCCAGTCTTTTA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGNLFRGKALSQAGVGRVTGDHM
GMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHRRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGAD
IVLKATKVDGVYSADPLKNSDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTIV
GANHDQ

Sequences:

>Translated_246_residues
MNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGNLFRGKALSQAGVGRVTGDHM
GMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHRRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGAD
IVLKATKVDGVYSADPLKNSDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTIV
GANHDQ
>Mature_246_residues
MNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGNLFRGKALSQAGVGRVTGDHM
GMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHRRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGAD
IVLKATKVDGVYSADPLKNSDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTIV
GANHDQ

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=237, Percent_Identity=60.7594936708861, Blast_Score=297, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26529; Mature: 26529

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGN
CCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEEECCC
LFRGKALSQAGVGRVTGDHMGMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHR
EECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
RKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGADIVLKATKVDGVYSADPLKNS
HHHHHHHCCCCEEEEEECCCCCCEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCC
DAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTIV
CCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCHHEEEE
GANHDQ
CCCCCC
>Mature Secondary Structure
MNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGN
CCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEEECCC
LFRGKALSQAGVGRVTGDHMGMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHR
EECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
RKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGADIVLKATKVDGVYSADPLKNS
HHHHHHHCCCCEEEEEECCCCCCEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCC
DAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTIV
CCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCHHEEEE
GANHDQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA