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The map label for this gene is tsf [H]

Identifier: 148359248

GI number: 148359248

Start: 1978851

End: 1979729

Strand: Reverse

Name: tsf [H]

Synonym: LPC_1142

Alternate gene names: 148359248

Gene position: 1979729-1978851 (Counterclockwise)

Preceding gene: 148359249

Following gene: 148359247

Centisome position: 55.35

GC content: 39.7

Gene sequence:

>879_bases
ATGTCAACAATTAGTGCTGCATTAGTAATGCAATTGCGTGAGCGCACAGGCGCAGGTATGATGGAATGTAAAAAATTTCT
AATAGCTACTAACGGTGATATCGAGCAAGCAATCATTGAAATGCGTAAAGCTGGCCAGGCAAAAGCAGACAAAAAGGCAG
ATAGAGTTGCAGCAGAAGGTATAATTGTTATTGCACGTTCTTCTGATGAACGTACAGCGGTAATGCTTGAGATTAATAGT
GAAACAGACTTTGTTGCGCGAGATGAGAATTTCACTAATTTTGCAAATGCTGTTGCCGATGTTGCATTAACCAGCCTTCC
AAAAAACATAGAAGACTTGTCCAATCAGGCATTATCTTCTGGTGCTACTGTTGAGCAAGCAAGACAGGAGCTGGTTGCTA
AAATTGGTGAAAATATTAAATTACGCCGATTGGAAAAAATGCACTGCGACGGTGTAATCGGGTATTATTTGCATGGTTCG
CGTATAGGAGTTATGGTCGCATTAAAAAATGGAAGTGAAGCATTGGCTAAAGATATTGCCATGCATGTTGCTGCCAGCAA
ACCGATGGTAGTTAGTCGTGATCAGGTACCAGCCGAAGCGATTGAAAACGAAAGAGAAATATTCACTGCTCAAGCAAAAG
AGAGTGGTAAGCCGCAAGAGATCATTGACAAGATGATTGATGGACGAATCAATAAATTTATTGATGAGGTAAGCTTGTTA
GGACAACCTTATGTAAAAGATCCTAACATTAAAGTGGGTCAACTTCTAAAAGAGAAAAATGCTGAAGTAATATCCTTTGT
TCGTTATGAAGTAGGGGAAGGAATAGAGAAAAAAGAGGACAATTTTGTTGAAGAAGTGATGGCTCAGGTTCGTACATGA

Upstream 100 bases:

>100_bases
CAAATTCTAATGAAGAAGAAAAATCCGGAGAATAATTACTATTTGAATAAAGGGGGCGTTAATTTAATAAGCCCCCTTTT
TGCTATGTGGAGAAATCAAA

Downstream 100 bases:

>100_bases
TGAATGAAAGTCAACCTAAATTAAAATACAAACGCATTCTGCTTAAATTTAGTGGTGAGGCGCTGATGGGGAAATCTCAA
TTTGGGATTGATCCTTCAGT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSTISAALVMQLRERTGAGMMECKKFLIATNGDIEQAIIEMRKAGQAKADKKADRVAAEGIIVIARSSDERTAVMLEINS
ETDFVARDENFTNFANAVADVALTSLPKNIEDLSNQALSSGATVEQARQELVAKIGENIKLRRLEKMHCDGVIGYYLHGS
RIGVMVALKNGSEALAKDIAMHVAASKPMVVSRDQVPAEAIENEREIFTAQAKESGKPQEIIDKMIDGRINKFIDEVSLL
GQPYVKDPNIKVGQLLKEKNAEVISFVRYEVGEGIEKKEDNFVEEVMAQVRT

Sequences:

>Translated_292_residues
MSTISAALVMQLRERTGAGMMECKKFLIATNGDIEQAIIEMRKAGQAKADKKADRVAAEGIIVIARSSDERTAVMLEINS
ETDFVARDENFTNFANAVADVALTSLPKNIEDLSNQALSSGATVEQARQELVAKIGENIKLRRLEKMHCDGVIGYYLHGS
RIGVMVALKNGSEALAKDIAMHVAASKPMVVSRDQVPAEAIENEREIFTAQAKESGKPQEIIDKMIDGRINKFIDEVSLL
GQPYVKDPNIKVGQLLKEKNAEVISFVRYEVGEGIEKKEDNFVEEVMAQVRT
>Mature_291_residues
STISAALVMQLRERTGAGMMECKKFLIATNGDIEQAIIEMRKAGQAKADKKADRVAAEGIIVIARSSDERTAVMLEINSE
TDFVARDENFTNFANAVADVALTSLPKNIEDLSNQALSSGATVEQARQELVAKIGENIKLRRLEKMHCDGVIGYYLHGSR
IGVMVALKNGSEALAKDIAMHVAASKPMVVSRDQVPAEAIENEREIFTAQAKESGKPQEIIDKMIDGRINKFIDEVSLLG
QPYVKDPNIKVGQLLKEKNAEVISFVRYEVGEGIEKKEDNFVEEVMAQVRT

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=312, Percent_Identity=26.9230769230769, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1786366, Length=288, Percent_Identity=52.7777777777778, Blast_Score=275, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17561440, Length=306, Percent_Identity=27.1241830065359, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19921466, Length=285, Percent_Identity=30.1754385964912, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 32112; Mature: 31981

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTISAALVMQLRERTGAGMMECKKFLIATNGDIEQAIIEMRKAGQAKADKKADRVAAEG
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCC
IIVIARSSDERTAVMLEINSETDFVARDENFTNFANAVADVALTSLPKNIEDLSNQALSS
EEEEEECCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GATVEQARQELVAKIGENIKLRRLEKMHCDGVIGYYLHGSRIGVMVALKNGSEALAKDIA
CCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHH
MHVAASKPMVVSRDQVPAEAIENEREIFTAQAKESGKPQEIIDKMIDGRINKFIDEVSLL
HHHHCCCCEEEECCCCCHHHHCCHHHHEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GQPYVKDPNIKVGQLLKEKNAEVISFVRYEVGEGIEKKEDNFVEEVMAQVRT
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STISAALVMQLRERTGAGMMECKKFLIATNGDIEQAIIEMRKAGQAKADKKADRVAAEG
CHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCC
IIVIARSSDERTAVMLEINSETDFVARDENFTNFANAVADVALTSLPKNIEDLSNQALSS
EEEEEECCCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GATVEQARQELVAKIGENIKLRRLEKMHCDGVIGYYLHGSRIGVMVALKNGSEALAKDIA
CCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHH
MHVAASKPMVVSRDQVPAEAIENEREIFTAQAKESGKPQEIIDKMIDGRINKFIDEVSLL
HHHHCCCCEEEECCCCCHHHHCCHHHHEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GQPYVKDPNIKVGQLLKEKNAEVISFVRYEVGEGIEKKEDNFVEEVMAQVRT
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA