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The map label for this gene is mviN [H]

Identifier: 147674115

GI number: 147674115

Start: 216819

End: 218396

Strand: Direct

Name: mviN [H]

Synonym: VC0395_A0212

Alternate gene names: 147674115

Gene position: 216819-218396 (Clockwise)

Preceding gene: 147675700

Following gene: 147675076

Centisome position: 7.17

GC content: 47.97

Gene sequence:

>1578_bases
TTGTTCGAGGTTACCGTGAGTAAACGCTTACTCAAGTCTGGCATCATTGTAAGTGCTATGACTTTGATTTCTCGTGTTTT
AGGTTTAGTGCGCGATGTGGTTGTGGCCAATTTGATGGGCGCAGGCGCCAGTGCTGACGTATTCTTTTTTGCCAACCGAA
TTCCCAATTTTTTACGCCGATTATTTGCAGAAGGGGCCTTCTCTCAAGCATTTGTCCCGGTATTAACCGAATATCATGCC
TCGGGTGATATCAATAAAACTCGAGATTTAATTGCGCGAGCGTCGGGAACTCTCGGTGTTTTAGTGACCATAGTGACGCT
AATTGGAGTGCTCGGCTCTGGCGCAGTCACCGCATTATTTGGCGCAGGTTGGTTCCTAGACTGGTTGAATGGGGGCCCTG
CTGCAGGAAAGTTTGAGTTAGCGAGCTTACTGCTCAAGATTACTTTTCCCTATTTGTGGTTTATCACCTTTGTTGCCTTG
TCTGGGGCAATTTTAAACACCTTAGGTAAGTTTGCTGTCTCCTCTTTCACGCCAGTTTTCTTGAACGTGATGATGATTCT
GTGTGCTTGGTACCTCTCGCCAAATCTAGAACAGCCGGAAGTGGGCTTAGCAATAGGCGTATTTTTAGGTGGTTTAGTCC
AGTTTTTATTTCAACTGCCATTTTTGATCAAGGCTGGAGTGCTGGTTAGGCCTAAATGGGGCTGGAAAGATCCTGGGGTG
GTGAAAATTCGCACACTGATGATTCCTGCACTGTTTGGAGTATCGGTCAGTCAAATCAACTTGTTATTTGACTCCTTCGT
GGCCAGTTTTCTGCAAACCGGTTCGATCAGCTGGCTCTATTATTCGGATCGCCTGCTGGAGTTTCCCCTCGGCTTATTTG
GAATTGCCATCGCGACGGTGATTTTGCCTGCCTTATCGCGTAAACATGTAGATGCGCACAGTGATGGGTTTGCCCACACC
ATGGACTGGGGGATTCGCATGGTTACGTTTCTCGGCATTCCTGCCATGCTGGGTTTGATGGTACTGGCAAAACCTATGCT
GATGGTGCTGTTTATGCGCGGGGAATTTACTTCAAGCGATGTAGAGCAAGCGTCCTATTCGTTACTCGCTTACTCATCTG
GCTTGCTCAGCTTTATGTTGATCAAAGTGTTAGCGCCGGGATATTACTCACGTCAAGACACGAAAACCCCCGTACGTTAC
GGAATTATCGCTATGGTCAGCAATATTGTGCTTAACGCAATCTTTGCGTGGTTTTACGGCTATGTTGGCTTGGCGGTCGC
GACTTCGATGTCCGCTTTCCTGAATATGGCACTGCTTTATCGTGGTTTGCACTTACAAGGTGTTTATCATCTGACTCGCA
AAACCGTCTGGTTTGTTGCGCGACTGGTGATGGCGGGAGCGGTAATGACTGGGGCGCTTTTGTGGCAGTTAGACACTATG
GCTACATGGTTGAGCTGGGGAATCAGTCAGCGCGCATTGACGCTGACAGGCTTGATTGGCCTTGGCGTGGCATCTTATCT
GGCTATTTTGCTGTTACTGGGTGTTCGTCTCAAAGATCTAAAAGCGGCGACAGAGTAG

Upstream 100 bases:

>100_bases
GGCGGGGATTCTATCAGCATTTTTTTACCAATGCTAATACTTATCTGATCTCACTATGACATTCTTATCCTTTCGAATCA
GATAATGTGGTTTTGACTCT

Downstream 100 bases:

>100_bases
CGAGCTTTAGGTATAATCCGCCAGTTTCGCACCATGAGAATCAAAATATAGGTTTTAAGCATCTTCCGATGGAATTAATA
CGCGGTATTCATAACATTCA

Product: MviN protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MFEVTVSKRLLKSGIIVSAMTLISRVLGLVRDVVVANLMGAGASADVFFFANRIPNFLRRLFAEGAFSQAFVPVLTEYHA
SGDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLDWLNGGPAAGKFELASLLLKITFPYLWFITFVAL
SGAILNTLGKFAVSSFTPVFLNVMMILCAWYLSPNLEQPEVGLAIGVFLGGLVQFLFQLPFLIKAGVLVRPKWGWKDPGV
VKIRTLMIPALFGVSVSQINLLFDSFVASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSDGFAHT
MDWGIRMVTFLGIPAMLGLMVLAKPMLMVLFMRGEFTSSDVEQASYSLLAYSSGLLSFMLIKVLAPGYYSRQDTKTPVRY
GIIAMVSNIVLNAIFAWFYGYVGLAVATSMSAFLNMALLYRGLHLQGVYHLTRKTVWFVARLVMAGAVMTGALLWQLDTM
ATWLSWGISQRALTLTGLIGLGVASYLAILLLLGVRLKDLKAATE

Sequences:

>Translated_525_residues
MFEVTVSKRLLKSGIIVSAMTLISRVLGLVRDVVVANLMGAGASADVFFFANRIPNFLRRLFAEGAFSQAFVPVLTEYHA
SGDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLDWLNGGPAAGKFELASLLLKITFPYLWFITFVAL
SGAILNTLGKFAVSSFTPVFLNVMMILCAWYLSPNLEQPEVGLAIGVFLGGLVQFLFQLPFLIKAGVLVRPKWGWKDPGV
VKIRTLMIPALFGVSVSQINLLFDSFVASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSDGFAHT
MDWGIRMVTFLGIPAMLGLMVLAKPMLMVLFMRGEFTSSDVEQASYSLLAYSSGLLSFMLIKVLAPGYYSRQDTKTPVRY
GIIAMVSNIVLNAIFAWFYGYVGLAVATSMSAFLNMALLYRGLHLQGVYHLTRKTVWFVARLVMAGAVMTGALLWQLDTM
ATWLSWGISQRALTLTGLIGLGVASYLAILLLLGVRLKDLKAATE
>Mature_525_residues
MFEVTVSKRLLKSGIIVSAMTLISRVLGLVRDVVVANLMGAGASADVFFFANRIPNFLRRLFAEGAFSQAFVPVLTEYHA
SGDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLDWLNGGPAAGKFELASLLLKITFPYLWFITFVAL
SGAILNTLGKFAVSSFTPVFLNVMMILCAWYLSPNLEQPEVGLAIGVFLGGLVQFLFQLPFLIKAGVLVRPKWGWKDPGV
VKIRTLMIPALFGVSVSQINLLFDSFVASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSDGFAHT
MDWGIRMVTFLGIPAMLGLMVLAKPMLMVLFMRGEFTSSDVEQASYSLLAYSSGLLSFMLIKVLAPGYYSRQDTKTPVRY
GIIAMVSNIVLNAIFAWFYGYVGLAVATSMSAFLNMALLYRGLHLQGVYHLTRKTVWFVARLVMAGAVMTGALLWQLDTM
ATWLSWGISQRALTLTGLIGLGVASYLAILLLLGVRLKDLKAATE

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=516, Percent_Identity=41.8604651162791, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 57172; Mature: 57172

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure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HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9457888; 10952301 [H]